Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human MEF2C Antibodies:
anti-Mouse (Murine) MEF2C Antibodies:
anti-Rat (Rattus) MEF2C Antibodies:
Go to our pre-filtered search.
Cow (Bovine) Polyclonal MEF2C Primary Antibody for WB - ABIN2780048
Shen, Kamp, Gruendling, Higgins: A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. in Genes & development 2006
Show all 8 Pubmed References
Human Polyclonal MEF2C Primary Antibody for ICC, IF - ABIN4333449
Wirrig, Hinton, Yutzey: Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. in Journal of molecular and cellular cardiology 2011
Show all 4 Pubmed References
Human Monoclonal MEF2C Primary Antibody for FACS, IHC - ABIN1098145
Xu, Cao, Wang, Xu, Chen, Xu: VEGF promotes the transcription of the human PRL-3 gene in HUVEC through transcription factor MEF2C. in PLoS ONE 2011
Show all 2 Pubmed References
variable transposon epigenetic silencing underlies the variable mef2ca mutant bone phenotype, and could be a widespread mechanism of phenotypic variability in animals.
Mef2 (show MYEF2 Antibodies) controls skeletal muscle formation after terminal differentiation.
Our study provides new insights in MEF2C conservation and provides the first evidence of mef2cb regulation by both transcriptional and post transcriptional mechanisms.
By selectively inhibiting translational initiation of mef2ca and other mRNAs, eIF4EBP3L reprograms the translational profile of muscle, enabling it to adjust to new environmental conditions.
find no evidence that the phenotypic stability in the wild type is provided by redundancy between mef2ca and its co-ortholog mef2cb, or that it is related to the selector (homeotic) gene function of mef2ca
Mef2ca single mutants have delayed heart development, but form an apparently normal heart. Mef2cb single mutants have a functional heart and are viable adults.
Data show that mef2cb is expressed in the late ventricular region, and is necessary for late myocardial addition to the arterial pole.
the genetic interaction of Tbx5 (show TBX5 Antibodies) and Mef2c is not only required for MYH6 (show MYH6 Antibodies) expression but also essential for the early stages of heart development and survival
Mef2c and Mef2d (show MEF2D Antibodies) are required for proper cardiac gene expression.
a MEF2C and CEBPA correlation in CML disease progression
Single nucleotide polymorphism in MEF2C gene is associated with major depressive disorder.
we identified novel associations in WLS (show WLS Antibodies) , ARHGAP1 (show ARHGAP1 Antibodies) , and 5' of MEF2C ( P- values < 8x10 - 5 ; false discovery rate (FDR) q-values < 0.01) that were much more strongly associated with BMD (show BEST1 Antibodies) compared to the GWAS SNPs.
Our analysis consistently identified significant sub-networks associated with the interacting transcription factors MEF2C and TWIST1 (show TWIST1 Antibodies), genes not previously associated with spontaneous preterm births , both of which regulate processes clearly relevant to birth timing.
Key role for miR (show MLXIP Antibodies)-214 in modulation of MEF2C-MYOCD (show MYOCD Antibodies)-LMOD1 (show LMOD1 Antibodies) signaling.
Endothelial Mef2c regulates the endothelial actin cytoskeleton and inhibits smooth muscle cell migration into the intima.
The mRNA expressions of PPP3CB and MEF2C were significantly up-regulated, and CAMK1 and PPP3R1 were significantly down-regulated in mitral regurgitation(MR) patients compared to normal subjects. Moreover, MR patients had significantly increased mRNA levels of PPP3CB, MEF2C and PLCE1 compared to aortic valve disease patients
Findings suggest that a single introduction of the three cardiomyogenic transcription factor (GATA4 (show GATA4 Antibodies), cand TBX5 (show TBX5 Antibodies))genes using polyethyleneimine (PEI)-based transfection is sufficient for transdifferentiation of adipose-derived stem cells (hADSCs) towards the cardiomyogenic lineage.
Mef2c is highly expressed in the retina where it modulates photoreceptor-specific gene expression
Study provides evidence that Mef2c cooperated with Sp1 (show PSG1 Antibodies) to activate human AQP1 (show AQP1 Antibodies) transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells indicating that AQP1 (show AQP1 Antibodies) is a direct target of Mef2c in regulating angiogenesis and vasculogenesis of endothelial cells.
The cDNA sequence was analyzed and the 5' upstream region of the mef2c gene was isolated from porcine genomic DNA.
analysis of sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle
Ca(2 (show CA2 Antibodies)+) signaling pathway increases Nr4a1 (show NR4A1 Antibodies) expression in MA-10 Leydig cells, at least in part, by enhancing the recruitment of coactivator most likely through the MEF2, AP1 (show JUN Antibodies), and CREB (show CREB1 Antibodies) transcription factors thus demonstrating an important interplay between the Ca(2 (show CA2 Antibodies)+) and cAMP pathways in regulating Nr4a1 (show NR4A1 Antibodies) expression.
HDAC5 (show HDAC5 Antibodies) emerges as a cellular conductor of MEF2C and M6a (show GPM6A Antibodies) activity and is regulated by miR (show MLXIP Antibodies)-124 and miR (show MLXIP Antibodies)-9 to control neurite development.
In cardiomyocytes exposed to biomechanical stimulation, FAK (show PTK2 Antibodies) accumulates in the nucleus, binds to and upregulates the transcriptional activity of MEF2c through an interaction with the FAK (show PTK2 Antibodies) focal adhesion targeting (FAT) domain.
In Fmr1 (show FMR1 Antibodies) KO neurons, Mdm2 (show MDM2 Antibodies) is hyperphosphorylated, nuclear localized basally, and unaffected by MEF2 activation, which our data suggest due to an enhanced interaction with Eukaryotic Elongation Factor (show TSFM Antibodies) 1alpha (EF1alpha), whose protein levels are elevated in Fmr1 (show FMR1 Antibodies) KO. Expression of a dephosphomimetic of Mdm2 (show MDM2 Antibodies) rescues PSD-95 (show DLG4 Antibodies) ubiquitination, degradation and synapse elimination in Fmr1 (show FMR1 Antibodies) KO neurons.
two MEF2 sites in the enhancer function cooperatively due to bridging of the MEF2C-bound sites by the SAP (show APCS Antibodies) domain-containing co-activator protein myocardin (show MYOCD Antibodies)
Our results elucidate the specific role of the transcription factors CREB (show CREB1 Antibodies), SRF, and MEF2 in the depression and potentiation components of ODP in vivo, therefore better informing future attempts to find therapeutic targets for diseases where activity-dependent plasticity is disrupted.
that Foxp2 (show FOXP2 Antibodies)-Mef2C signaling is critical to corticostriatal circuit formation
Postnatal, postsynaptic deletion of Mef2c in a sparse population of L2/3 neurons suppressed development of excitatory synaptic connections from all local input pathways tested. In the same cell population, Mef2c deletion promoted the strength of excitatory inputs originating from contralateral neocortex. Both the synapse promoting and synapse suppressing effects of Mef2c deletion required normal whisking experience.
Critical role for MEF2C in the regulation of spine numbers with a dissociation of learning and memory, synaptic plasticity, and measures of autism-related behaviors in postnatal mouse brain.
This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
myocyte-specific enhancer factor 2C
, myocyte enhancer factor 2C
, myocyte-specific enhancer factor 2C-like
, MADS box transcription enhancer factor 2, polypeptide C
, MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)
, Myocyte enhancer factor 2C protein
, myocyte enhancer factor 2c