MEF2C antibody (AA 1-125)

Catalog No. ABIN1846463

The Mouse Monoclonal anti-MEF2C antibody is suitable to detect MEF2C in samples from Human and Mouse. It has been validated for WB, ELISA, IHC and FACS.

Quick Overview for MEF2C antibody (AA 1-125) (ABIN1846463)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-MEF2C Antibody

Binding Specificity: AA 1-125

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MEF2C (AA: 1-125) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Molecular Weight: 51.2 kDa

Gene ID: 4208

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling