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Browse our MEF2C Proteins (MEF2C)

Full name:
Myocyte Enhancer Factor 2C Proteins (MEF2C)
On are 6 Myocyte Enhancer Factor 2C (MEF2C) Proteins from 4 different suppliers available. Additionally we are shipping MEF2C Antibodies (313) and MEF2C Kits (7) and many more products for this protein. A total of 340 MEF2C products are currently listed.
5430401D19Rik, 9930028G15Rik, AV011172, C5DELq14.3, DEL5q14.3, id:ibd5026, Mef2, mef2c, RGD1563119, si:ch211-202e12.2, wu:fc05b06, XMEF2C, zgc:64184, zgc:85726
list all proteins Gene Name GeneID UniProt
MEF2C 4208 Q06413
MEF2C 17260 Q8CFN5
Rat MEF2C MEF2C 499497  

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MEF2C Proteins (MEF2C) by Origin

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More Proteins for MEF2C Interaction Partners

Zebrafish Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. Our study provides new insights in MEF2C conservation and provides the first evidence of mef2cb regulation by both transcriptional and post transcriptional mechanisms.

  2. mef2ca transcripts including exon 5 (mef2ca 4-5-6) are present early in the embryo. Over-expression of this isoform alters the expression of genes involved in early dorso-ventral patterning of the embryo and induces severe developmental defects

  3. By selectively inhibiting translational initiation of mef2ca and other mRNAs, eIF4EBP3L reprograms the translational profile of muscle, enabling it to adjust to new environmental conditions.

  4. find no evidence that the phenotypic stability in the wild type is provided by redundancy between mef2ca and its co-ortholog mef2cb, or that it is related to the selector (homeotic) gene function of mef2ca

  5. Mef2ca single mutants have delayed heart development, but form an apparently normal heart. Mef2cb single mutants have a functional heart and are viable adults.

  6. Data show that mef2cb is expressed in the late ventricular region, and is necessary for late myocardial addition to the arterial pole.

  7. the genetic interaction of Tbx5 (show TBX5 Proteins) and Mef2c is not only required for MYH6 (show MYH6 Proteins) expression but also essential for the early stages of heart development and survival

Xenopus laevis Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. Mef2c and Mef2d (show MEF2D Proteins) are required for proper cardiac gene expression.

Human Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. MiR (show MLXIP Proteins)-135b-5p and MiR (show MLXIP Proteins)-499a-3p Promote Cell Proliferation and Migration in Atherosclerosis by Directly Targeting MEF2C

  2. early B cell factor-1 (EBF1 (show EBF1 Proteins)) was identified as a co-regulator of gene expression with MEF2C.

  3. Data show that high myocyte enhancer factor 2C (MEF2C) mRNA expression leads to overexpression of MEF2C protein, and these findings provide the rationale for therapeutic targeting of MEF2C transcriptional activation in acute myeloid leukemia (show BCL11A Proteins).

  4. this is the first report of a Greek-Cypriot patient with a MEF2C-related phenotype highlighting the rich variability in phenotypic expression and the ethnic diversity associated with this condition.

  5. BCL2 (show BCL2 Proteins) inhibitors may be a therapeutic candidate in vivo for patients with ETP-ALL with high expression levels of MEF2C.

  6. MEF2C regulates the expression of G2/M checkpoint genes (14-3-3gamma (show YWHAG Proteins), Gadd45b (show GADD45B Proteins) and p21 (show CDKN1A Proteins)) and the sub-cellular localization of CYCLIN B1 (show CCNB1 Proteins).

  7. The overall effect of MEF2C in hepatocellular carcinoma progression regulation was dictated by its subcellular distribution.

  8. MEF2C/alpha-2-macroglobulin (show A2M Proteins) axis functions in endothelial cells as a negative feed-back mechanism that adapts sprouting activity to the oxygen concentration thus diminishing inappropriate and excess angiogenesis.

  9. MEF2C and MEF2D interact with the E3 ligase F-box protein SKP2, which mediates their subsequent degradation through the ubiquitin-proteasome system.

  10. Single nucleotide polymorphisms in ALDOB (show ALDOB Proteins), MAP3K1 (show MAP3K1 Proteins), and MEF2C are associated with cataract.

Pig (Porcine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. The cDNA sequence was analyzed and the 5' upstream region of the mef2c gene was isolated from porcine genomic DNA.

Cow (Bovine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. analysis of sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle

Mouse (Murine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. Data show that three transcriptional factors Gata4 (show GATA4 Proteins), Mef2c, and Tbx5 (show TBX5 Proteins) (abbreviated as GMT (show GAMT Proteins)) significantly improved murine embryonic stem cells (ESCs (show NR2E3 Proteins)) differentiated into cardiomyocytes.

  2. MEF2C has a role in regulating outflow tract alignment and transcriptional control of Tdgf1 (show TDGF1 Proteins)

  3. These findings uncover a novel role for Mef2c/d in coordinating the transcriptional network that promotes early B-cell development.

  4. our data indicate that robust hypertrophic MEF2 activation in the heart in vivo requires a background of adiponectin (show ADIPOQ Proteins) signaling and that adiponectin (show ADIPOQ Proteins) signaling in primary isolated CM directly enhances MEF2 activity through activation of p38 MAPK (show MAPK14 Proteins)

  5. SmarcA4 (show SMARCA4 Proteins) is required for synapse development and myocyte enhancer factor 2-mediated synapse remodeling

  6. Our results identify novel target genes for MEF2 and define MEF2 as an important regulator of Leydig cell function and male reproduction.

  7. this is a novel mechanism of H2S-mediated activation of MEF2C and induction of miR (show MLXIP Proteins)-133a and inhibition of hypertrophy in HHcy cardiomyocytes.

  8. The RBM4-MEF2C-miR-1 network constitutes a novel mechanism which programs the gene expression profile toward the development of brown adipocytes.

  9. increased sclerostin (show SOST Proteins) production achieved by HDAC5 (show HDAC5 Proteins) shRNA is abrogated by simultaneous knockdown of MEF2C, indicating that MEF2C is a major target of HDAC5 (show HDAC5 Proteins) in osteocytes

  10. Endothelin signaling activates Mef2c expression in the neural crest through a MEF2C-dependent positive-feedback transcriptional pathway.

MEF2C Protein Profile

Protein Summary

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with MEF2C

  • myocyte enhancer factor 2C (MEF2C)
  • MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (mef2c)
  • myocyte enhancer factor 2cb (mef2cb)
  • myocyte enhancer factor 2C (Mef2c)
  • myocyte enhancer factor 2ca (mef2ca)
  • 5430401D19Rik protein
  • 9930028G15Rik protein
  • AV011172 protein
  • C5DELq14.3 protein
  • DEL5q14.3 protein
  • id:ibd5026 protein
  • Mef2 protein
  • mef2c protein
  • RGD1563119 protein
  • si:ch211-202e12.2 protein
  • wu:fc05b06 protein
  • XMEF2C protein
  • zgc:64184 protein
  • zgc:85726 protein

Protein level used designations for MEF2C

myocyte-specific enhancer factor 2C , myocyte enhancer factor 2C , myocyte-specific enhancer factor 2C-like , MADS box transcription enhancer factor 2, polypeptide C , MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) , Myocyte enhancer factor 2C protein , hoo , hoover , myocyte enhancer factor 2c

100286738 Ovis aries
461760 Pan troglodytes
694992 Macaca mulatta
100065153 Equus caballus
100079500 Ornithorhynchus anatinus
100127198 Xenopus (Silurana) tropicalis
100218659 Taeniopygia guttata
100413265 Callithrix jacchus
100464632 Ailuropoda melanoleuca
100585129 Nomascus leucogenys
798771 Danio rerio
100174751 Pongo abelii
444310 Xenopus laevis
4208 Homo sapiens
479155 Canis lupus familiaris
733590 Sus scrofa
512254 Bos taurus
17260 Mus musculus
499497 Rattus norvegicus
769007 Gallus gallus
30575 Danio rerio
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