Browse our MEF2C Proteins (MEF2C)

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Myocyte Enhancer Factor 2C Proteins (MEF2C)
On are 6 Myocyte Enhancer Factor 2C (MEF2C) Proteins from 4 different suppliers available. Additionally we are shipping MEF2C Antibodies (346) and MEF2C Kits (5) and many more products for this protein. A total of 372 MEF2C products are currently listed.
5430401D19Rik, 9930028G15Rik, AV011172, C5DELq14.3, DEL5q14.3, id:ibd5026, Mef2, mef2c, RGD1563119, si:ch211-202e12.2, wu:fc05b06, XMEF2C, zgc:64184, zgc:85726
list all proteins Gene Name GeneID UniProt
MEF2C 4208 Q06413
MEF2C 17260 Q8CFN5
Rat MEF2C MEF2C 499497  

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MEF2C Proteins (MEF2C) by Origin

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More Proteins for MEF2C Interaction Partners

Zebrafish Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. variable transposon epigenetic silencing underlies the variable mef2ca mutant bone phenotype, and could be a widespread mechanism of phenotypic variability in animals.

  2. Mef2 (show MYEF2 Proteins) controls skeletal muscle formation after terminal differentiation.

  3. Our study provides new insights in MEF2C conservation and provides the first evidence of mef2cb regulation by both transcriptional and post transcriptional mechanisms.

  4. By selectively inhibiting translational initiation of mef2ca and other mRNAs, eIF4EBP3L reprograms the translational profile of muscle, enabling it to adjust to new environmental conditions.

  5. find no evidence that the phenotypic stability in the wild type is provided by redundancy between mef2ca and its co-ortholog mef2cb, or that it is related to the selector (homeotic) gene function of mef2ca

  6. Mef2ca single mutants have delayed heart development, but form an apparently normal heart. Mef2cb single mutants have a functional heart and are viable adults.

  7. Data show that mef2cb is expressed in the late ventricular region, and is necessary for late myocardial addition to the arterial pole.

  8. the genetic interaction of Tbx5 (show TBX5 Proteins) and Mef2c is not only required for MYH6 (show MYH6 Proteins) expression but also essential for the early stages of heart development and survival

Xenopus laevis Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. Mef2c and Mef2d (show MEF2D Proteins) are required for proper cardiac gene expression.

Human Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. Single nucleotide polymorphism in MEF2C gene is associated with major depressive disorder.

  2. we identified novel associations in WLS (show WLS Proteins) , ARHGAP1 (show ARHGAP1 Proteins) , and 5' of MEF2C ( P- values < 8x10 - 5 ; false discovery rate (FDR) q-values < 0.01) that were much more strongly associated with BMD (show BEST1 Proteins) compared to the GWAS SNPs.

  3. Our analysis consistently identified significant sub-networks associated with the interacting transcription factors MEF2C and TWIST1 (show TWIST1 Proteins), genes not previously associated with spontaneous preterm births , both of which regulate processes clearly relevant to birth timing.

  4. Key role for miR (show MLXIP Proteins)-214 in modulation of MEF2C-MYOCD-LMOD1 (show LMOD1 Proteins) signaling.

  5. Endothelial Mef2c regulates the endothelial actin cytoskeleton and inhibits smooth muscle cell migration into the intima.

  6. The mRNA expressions of PPP3CB (show PPP3CB Proteins) and MEF2C were significantly up-regulated, and CAMK1 (show CAMK1 Proteins) and PPP3R1 (show PPP3R1 Proteins) were significantly down-regulated in mitral regurgitation(MR) patients compared to normal subjects. Moreover, MR patients had significantly increased mRNA levels of PPP3CB (show PPP3CB Proteins), MEF2C and PLCE1 (show PLCE1 Proteins) compared to aortic valve disease patients

  7. Findings suggest that a single introduction of the three cardiomyogenic transcription factor (GATA4 (show GATA4 Proteins), cand TBX5 (show TBX5 Proteins))genes using polyethyleneimine (PEI)-based transfection is sufficient for transdifferentiation of adipose-derived stem cells (hADSCs) towards the cardiomyogenic lineage.

  8. Mef2c is highly expressed in the retina where it modulates photoreceptor-specific gene expression

  9. Study provides evidence that Mef2c cooperated with Sp1 (show PSG1 Proteins) to activate human AQP1 (show AQP1 Proteins) transcription by binding to its proximal promoter in human umbilical cord vein endothelial cells indicating that AQP1 (show AQP1 Proteins) is a direct target of Mef2c in regulating angiogenesis and vasculogenesis of endothelial cells.

  10. Data show that microRNA miR (show MLXIP Proteins)-27a was essential for the shift of mesenchymal stem cells (MSCs) from osteogenic differentiation to adipogenic differentiation in osteoporosis by targeting myocyte enhancer factor 2 c (Mef2c).

Pig (Porcine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. The cDNA sequence was analyzed and the 5' upstream region of the mef2c gene was isolated from porcine genomic DNA.

Cow (Bovine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. analysis of sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle

Mouse (Murine) Myocyte Enhancer Factor 2C (MEF2C) interaction partners

  1. In Fmr1 (show FMR1 Proteins) KO neurons, Mdm2 (show MDM2 Proteins) is hyperphosphorylated, nuclear localized basally, and unaffected by MEF2 activation, which our data suggest due to an enhanced interaction with Eukaryotic Elongation Factor (show TSFM Proteins) 1alpha (EF1alpha), whose protein levels are elevated in Fmr1 (show FMR1 Proteins) KO. Expression of a dephosphomimetic of Mdm2 (show MDM2 Proteins) rescues PSD-95 (show DLG4 Proteins) ubiquitination, degradation and synapse elimination in Fmr1 (show FMR1 Proteins) KO neurons.

  2. two MEF2 sites in the enhancer function cooperatively due to bridging of the MEF2C-bound sites by the SAP domain-containing co-activator protein myocardin

  3. Our results elucidate the specific role of the transcription factors CREB (show CREB1 Proteins), SRF, and MEF2 in the depression and potentiation components of ODP in vivo, therefore better informing future attempts to find therapeutic targets for diseases where activity-dependent plasticity is disrupted.

  4. that Foxp2 (show FOXP2 Proteins)-Mef2C signaling is critical to corticostriatal circuit formation

  5. Postnatal, postsynaptic deletion of Mef2c in a sparse population of L2/3 neurons suppressed development of excitatory synaptic connections from all local input pathways tested. In the same cell population, Mef2c deletion promoted the strength of excitatory inputs originating from contralateral neocortex. Both the synapse promoting and synapse suppressing effects of Mef2c deletion required normal whisking experience.

  6. Critical role for MEF2C in the regulation of spine numbers with a dissociation of learning and memory, synaptic plasticity, and measures of autism-related behaviors in postnatal mouse brain.

  7. Endothelial Mef2c regulates the endothelial actin cytoskeleton and inhibits smooth muscle cell migration into the intima.

  8. Analysis of SOST (show SOST Proteins) expression using large minigenes reveals the MEF2C binding site in the evolutionarily conserved region (ECR5) enhancer mediates forskolin, but not 1,25-dihydroxyvitamin D3 or TGFbeta1 (show TGFB1 Proteins) responsiveness.

  9. Mef2c is highly expressed in the retina where it modulates photoreceptor-specific gene expression

  10. results identify a novel cooperation between MEF2 factors and NR2F2 (show NR2F2 Proteins) in the expression of the Akr1c14 gene

MEF2C Protein Profile

Protein Summary

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with MEF2C

  • myocyte enhancer factor 2C (MEF2C)
  • MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) (mef2c)
  • myocyte enhancer factor 2cb (mef2cb)
  • myocyte enhancer factor 2C (Mef2c)
  • myocyte enhancer factor 2ca (mef2ca)
  • 5430401D19Rik protein
  • 9930028G15Rik protein
  • AV011172 protein
  • C5DELq14.3 protein
  • DEL5q14.3 protein
  • id:ibd5026 protein
  • Mef2 protein
  • mef2c protein
  • RGD1563119 protein
  • si:ch211-202e12.2 protein
  • wu:fc05b06 protein
  • XMEF2C protein
  • zgc:64184 protein
  • zgc:85726 protein

Protein level used designations for MEF2C

myocyte-specific enhancer factor 2C , myocyte enhancer factor 2C , myocyte-specific enhancer factor 2C-like , MADS box transcription enhancer factor 2, polypeptide C , MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C) , Myocyte enhancer factor 2C protein , hoo , hoover , myocyte enhancer factor 2c

100286738 Ovis aries
461760 Pan troglodytes
694992 Macaca mulatta
100065153 Equus caballus
100079500 Ornithorhynchus anatinus
100127198 Xenopus (Silurana) tropicalis
100218659 Taeniopygia guttata
100413265 Callithrix jacchus
100464632 Ailuropoda melanoleuca
100585129 Nomascus leucogenys
798771 Danio rerio
100174751 Pongo abelii
444310 Xenopus laevis
4208 Homo sapiens
479155 Canis lupus familiaris
733590 Sus scrofa
512254 Bos taurus
17260 Mus musculus
499497 Rattus norvegicus
769007 Gallus gallus
30575 Danio rerio
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