Browse our anti-Sortilin 1 (SORT1) Antibodies

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anti-Sortilin 1 Antibodies (SORT1)
On are 85 Sortilin 1 (SORT1) Antibodies from 14 different suppliers available. Additionally we are shipping Sortilin 1 Kits (13) and Sortilin 1 Proteins (7) and many more products for this protein. A total of 108 Sortilin 1 products are currently listed.
19.m02079, 2900053A11Rik, AI852375, Gp95, LDLCQ6, Nt3, Ntr3, Nts3, Ntsr3, sort1, sortilin, zgc:85953
list all antibodies Gene Name GeneID UniProt
SORT1 6272 Q99523
SORT1 20661 Q6PHU5
SORT1 83576 O54861

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anti-Human Sortilin 1 Antibodies:

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anti-Rat (Rattus) Sortilin 1 Antibodies:

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Top referenced anti-Sortilin 1 Antibodies

  1. Human Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350865 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)
    Show all 10 references for 350865

  2. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350869 : Chen, Ieraci, Teng, Dall, Meng, Herrera, Nykjaer, Hempstead, Lee: Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)
    Show all 6 references for 350869

  3. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350866 : Conticello, Kowalsman, Jacobsen, Yudkovsky, Sato, Elazar, Petersen, Aronheim, Fainzilber: The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors. in The Journal of biological chemistry 2003 (PubMed)
    Show all 6 references for 350866

  4. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350868 : Gibbs, Weinstock, Metzker, Muzny, Sodergren, Scherer, Scott, Steffen, Worley, Burch, Okwuonu, Hines, Lewis, DeRamo, Delgado, Dugan-Rocha, Miner, Morgan, Hawes, Gill, Celera, Holt, Adams, Amanatides et al.: Genome sequence of the Brown Norway rat yields insights into mammalian evolution. ... in Nature 2004 (PubMed)
    Show all 6 references for 350868

  5. Chicken Monoclonal Sortilin 1 Primary Antibody for IF, WB - ABIN968737 : Mazella, Zsürger, Navarro, Chabry, Kaghad, Caput, Ferrara, Vita, Gully, Maffrand, Vincent: The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for 968737

More Antibodies against Sortilin 1 Interaction Partners

Xenopus laevis Sortilin 1 (SORT1) interaction partners

  1. sortilin negatively regulates TGF-beta (show TGFB1 Antibodies) signaling by diverting trafficking of precursor proteins to the lysosome during transit through the biosynthetic pathway

Human Sortilin 1 (SORT1) interaction partners

  1. SORT1 single nucleotide polymorphism and it's association with LDL cholesterol level and risk of coronary heart disease in Pakistani population

  2. Four SNPs within the APOE (show APOE Antibodies) cluster (rs7412, rs4420638), ABCC2 (show ABCC2 Antibodies) (rs2002042) and CELSR/SORT1/PSRC1 (show PSRC1 Antibodies) (rs646776), displayed a major impact on statin efficacy. The wGRS was significantly associated with lower LDL-C at age 75 and 80

  3. In older men, higher serum sortilin levels associated with higher major adverse cerebrovascular/cardiovascular disease risk and severe abdominal aortic calcification.

  4. sortilin is a PIP3 binding protein with binding likely to occur at the C-terminal neurotensin (show NTS Antibodies) binding site, and is a competitor of neurotensin (show NTS Antibodies)

  5. Focal adhesion kinase-sortilin interactions have an important role in colorectal cancer cells dissociation. (Review)

  6. TDP-43 (show TARDBP Antibodies) functions within a network of hnRNP (show HNRNPC Antibodies) proteins to inhibit the production of a truncated human SORT1 receptor.

  7. no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2 (show CELSR2 Antibodies)-PSRC1 (show PSRC1 Antibodies)-SORT1 and the risk of coronary artery disease or ischemic stroke

  8. Inverse association between hepatic SORT1 gene expression and hepatic HBsAg expression indicates the possible role of sortilin in HBsAg particle formation.

  9. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

  10. Sortilin has been found to inhibit the conversion of proBDNF into mature BDNF (show BDNF Antibodies) by plasmin (show PLG Antibodies) and to protect neurons from the apoptotic properties of proBDNF.

Mouse (Murine) Sortilin 1 (SORT1) interaction partners

  1. Shh (show SHH Antibodies) and Sort1 can interact at the level of the Golgi and that Sort1 directs Shh (show SHH Antibodies) away from the pathways that promote its secretion.

  2. By contrast, treatment with dexamethasone, which also induced insulin (show INS Antibodies) resistance, was without effect on sortilin expression and PE production. As a putative bioactive peptide, we have evaluated its autocrine effect by the use of spadin on 3T3-L1 adipocytes by performing glucose uptake and signalling experiments. Any effect was measured on adipocytes indicating that the use of spadin as an antidepressant would have no side

  3. Sortilin 1 (Sort1) knockout (KO) does not affect Western diet-induced obesity nor adipose fatty acid and ceramide concentrations.

  4. sortilin regulates cholestatic liver damage and fibrosis via effects on both aSMase (show SMPD1 Antibodies) activity and serum IL-6 (show IL6 Antibodies).

  5. This study demonstrated that Mice with Sort1 deficiency display normal cognition but elevated anxiety-like behavior.

  6. TDP-43 (show TARDBP Antibodies) functions within a network of hnRNP (show HNRNPH2 Antibodies) proteins to inhibit the production of a truncated human SORT1 receptor.

  7. Sortilin is highly expressed in epithelial tissues of the developing lung, nasal cavity, kidney, pancreas and salivary gland.

  8. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

  9. Sortilin deficiency induces a beneficial metabolic phenotype in liver and adipose tissue upon DIO, mediated in part by reduced aSMase (show SMPD1 Antibodies) activity.

  10. Overexpression of SORT1 was shown to reduce Very-Low-Density Lipoproteins , Triglyceride and Apolipoprotein B (show APOB Antibodies) secretion in mice.

Sortilin 1 (SORT1) Antigen Profile

Antigen Summary

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes\; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p\; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.

Alternative names and synonyms associated with Sortilin 1 (SORT1)

  • sortilin 1 (SORT1) antibody
  • sortilin (TP01_0016) antibody
  • sortilin (BBOV_I002730) antibody
  • sortilin 1 (sort1) antibody
  • sortilin 1 (Sort1) antibody
  • sortilin 1a (sort1a) antibody
  • 19.m02079 antibody
  • 2900053A11Rik antibody
  • AI852375 antibody
  • Gp95 antibody
  • LDLCQ6 antibody
  • Nt3 antibody
  • Ntr3 antibody
  • Nts3 antibody
  • Ntsr3 antibody
  • sort1 antibody
  • sortilin antibody
  • zgc:85953 antibody

Protein level used designations for anti-Sortilin 1 (SORT1) Antibodies

sortilin 1 , sortilin , sortilin-like , 100 kDa NT receptor , NTR3 , glycoprotein 95 , neurotensin receptor 3 , mNTR3 , glycoprotein 110 , gp110

457090 Pan troglodytes
3502711 Theileria parva strain Muguga
5477139 Babesia bovis T2Bo
100158281 Xenopus laevis
100457993 Pongo abelii
6272 Homo sapiens
20661 Mus musculus
83576 Rattus norvegicus
406511 Danio rerio
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