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Browse our anti-Sortilin 1 (SORT1) Antibodies

Full name:
anti-Sortilin 1 Antibodies (SORT1)
On www.antibodies-online.com are 68 Sortilin 1 (SORT1) Antibodies from 12 different suppliers available. Additionally we are shipping Sortilin 1 Kits (10) and Sortilin 1 Proteins (6) and many more products for this protein. A total of 86 Sortilin 1 products are currently listed.
Synonyms:
19.m02079, 2900053A11Rik, AI852375, Gp95, LDLCQ6, Nt3, Ntr3, Nts3, Ntsr3, sort1, sortilin, zgc:85953
list all antibodies Gene Name GeneID UniProt
SORT1 6272 Q99523
SORT1 20661 Q6PHU5
SORT1 83576 O54861

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Most Popular Reactivities for anti-Sortilin 1 (SORT1) Antibodies

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anti-Human Sortilin 1 Antibodies:

anti-Mouse (Murine) Sortilin 1 Antibodies:

anti-Rat (Rattus) Sortilin 1 Antibodies:

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Top referenced anti-Sortilin 1 Antibodies

  1. Human Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350864 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)
    Show all 10 references for ABIN350864

  2. Human Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350872 : Maeda, Nobukuni, Shimo-Onoda, Hayashi, Yone, Komiya, Inoue: Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization. in Journal of cellular physiology 2002 (PubMed)
    Show all 10 references for ABIN350872

  3. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350870 : Chen, Ieraci, Teng, Dall, Meng, Herrera, Nykjaer, Hempstead, Lee: Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2005 (PubMed)
    Show all 6 references for ABIN350870

  4. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350869 : Conticello, Kowalsman, Jacobsen, Yudkovsky, Sato, Elazar, Petersen, Aronheim, Fainzilber: The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors. in The Journal of biological chemistry 2003 (PubMed)
    Show all 6 references for ABIN350869

  5. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350866 : Gibbs, Weinstock, Metzker, Muzny, Sodergren, Scherer, Scott, Steffen, Worley, Burch, Okwuonu, Hines, Lewis, DeRamo, Delgado, Dugan-Rocha, Miner, Morgan, Hawes, Gill, Celera, Holt, Adams, Amanatides et al.: Genome sequence of the Brown Norway rat yields insights into mammalian evolution. ... in Nature 2004 (PubMed)
    Show all 6 references for ABIN350866

  6. Rat (Rattus) Polyclonal Sortilin 1 Primary Antibody for IHC, WB - ABIN350868 : Lin, Pilch, Kandror: Sortilin is a major protein component of Glut4-containing vesicles. in The Journal of biological chemistry 1997 (PubMed)
    Show all 6 references for ABIN350868

  7. Chicken Monoclonal Sortilin 1 Primary Antibody for IF, WB - ABIN968737 : Mazella, Zsürger, Navarro, Chabry, Kaghad, Caput, Ferrara, Vita, Gully, Maffrand, Vincent: The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. in The Journal of biological chemistry 1998 (PubMed)
    Show all 4 references for ABIN968737

More Antibodies against Sortilin 1 Interaction Partners

Xenopus laevis Sortilin 1 (SORT1) interaction partners

  1. sortilin negatively regulates TGF-beta (show TGFB1 Antibodies) signaling by diverting trafficking of precursor proteins to the lysosome during transit through the biosynthetic pathway

Human Sortilin 1 (SORT1) interaction partners

  1. no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2 (show CELSR2 Antibodies)-PSRC1 (show PSRC1 Antibodies)-SORT1 and the risk of coronary artery disease or ischemic stroke

  2. Inverse association between hepatic SORT1 gene expression and hepatic HBsAg expression indicates the possible role of sortilin in HBsAg particle formation.

  3. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

  4. Sortilin has been found to inhibit the conversion of proBDNF into mature BDNF (show BDNF Antibodies) by plasmin (show PLG Antibodies) and to protect neurons from the apoptotic properties of proBDNF.

  5. Variants near SORT1 is associated with dyslipidemia.

  6. SNPs in SORT1, CETP (show CETP Antibodies) and GCKR (show GCKR Antibodies) were individually associated with lipid level variations in Algerian population.

  7. The study demostrated that the sortilin deficiency caused by the SORT1 p.G171A mutation may lead to defects in neurotransmission, giving rise to the development of tremor.

  8. Prosaposin (show PSAP Antibodies) facilitates sortilin-independent lysosomal trafficking of progranulin (show GRN Antibodies).

  9. We conclude that PCSK9 (show PCSK9 Antibodies) enhances the degradation of the LDLR (show LDLR Antibodies) independently of either APLP2 (show APLP2 Antibodies) or sortilin both ex vivo and in mice.

  10. NRH2 (show NRADD Antibodies) enhanced the ratio of Bax (show BAX Antibodies)/Bcl-2 (show BCL2 Antibodies) by promoting the expressions of proNGF, sortilin and p75NTR (show NGFR Antibodies), thereby inducing brain cell apoptosis.

Mouse (Murine) Sortilin 1 (SORT1) interaction partners

  1. Sortilin mediates vascular calcification via its recruitment into extracellular vesicles.

  2. Sortilin deficiency induces a beneficial metabolic phenotype in liver and adipose tissue upon DIO, mediated in part by reduced aSMase (show SMPD1 Antibodies) activity.

  3. Overexpression of SORT1 was shown to reduce Very-Low-Density Lipoproteins , Triglyceride and Apolipoprotein B (show APOB Antibodies) secretion in mice.

  4. Prosaposin (show PSAP Antibodies) facilitates sortilin-independent lysosomal trafficking of progranulin (show GRN Antibodies).

  5. sortilin influences cytokine secretion and that targeting sortilin in immune cells attenuates inflammation and reduces atherosclerosis.

  6. Sort1 may play a role in altered hepatic apoB100 (show APOB Antibodies) metabolism in insulin (show INS Antibodies)-resistant conditions

  7. sigma1B adaptin (show AP1S2 Antibodies) regulates adipogenesis by mediating the sorting of sortilin in adipose tissue.

  8. Sortilin-deficient macrophages had significantly reduced uptake of native LDL ex vivo and reduced foam cell formation in vivo, whereas sortilin overexpression in macrophages resulted in increased LDL uptake and foam cell formation.

  9. Sortilin ectopically expressed in undifferentiated cells was translocated to the plasma membrane regardless of the presence or absence of myc7-Glut4 (show SLC2A4 Antibodies)

  10. Increased saturated fatty acids downregulate liver Sort1 protein, which may contribute to the development of dyslipidemia in obesity and diabetes.

Sortilin 1 (SORT1) Antigen Profile

Antigen Summary

This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes\; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p\; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.

Alternative names and synonyms associated with Sortilin 1 (SORT1)

  • sortilin 1 (SORT1) antibody
  • sortilin (TP01_0016) antibody
  • sortilin (BBOV_I002730) antibody
  • sortilin 1 (sort1) antibody
  • sortilin 1 (Sort1) antibody
  • sortilin 1a (sort1a) antibody
  • 19.m02079 antibody
  • 2900053A11Rik antibody
  • AI852375 antibody
  • Gp95 antibody
  • LDLCQ6 antibody
  • Nt3 antibody
  • Ntr3 antibody
  • Nts3 antibody
  • Ntsr3 antibody
  • sort1 antibody
  • sortilin antibody
  • zgc:85953 antibody

Protein level used designations for anti-Sortilin 1 (SORT1) Antibodies

sortilin 1 , sortilin , sortilin-like , 100 kDa NT receptor , NTR3 , glycoprotein 95 , neurotensin receptor 3 , mNTR3 , glycoprotein 110 , gp110

GENE ID SPECIES
457090 Pan troglodytes
3502711 Theileria parva strain Muguga
5477139 Babesia bovis T2Bo
100158281 Xenopus laevis
100457993 Pongo abelii
6272 Homo sapiens
20661 Mus musculus
83576 Rattus norvegicus
406511 Danio rerio
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