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Rat (Rattus) Insulin ELISA Kit for Competition ELISA - ABIN416266
Nascimento da Silva, Azevedo de Jesuz, De Salvo Castro, Soares da Costa, Teles Boaventura, Blondet de Azeredo: Effect of the “protein diet” and bone tissue. in Nutrición hospitalaria 2014
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Rat (Rattus) Insulin ELISA Kit for Sandwich ELISA - ABIN366470
Wang, Luo, Wang, Li, Wang, Sun, Zhang, Su, Ma, Zeng, Wang, Ren, Cao: Glucagon-like peptide-1 protects against cardiac microvascular injury in diabetes via a cAMP/PKA/Rho-dependent mechanism. in Diabetes 2013
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Mouse (Murine) Insulin ELISA Kit for Sandwich ELISA - ABIN366323
Guo, Zhu, Wang, Fan, Lu, Wang, Zhu, Wang, Huang: Combined transfection of the three transcriptional factors, PDX-1, NeuroD1, and MafA, causes differentiation of bone marrow mesenchymal stem cells into insulin-producing cells. in Experimental diabetes research 2012
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Human Insulin ELISA Kit for Sandwich ELISA - ABIN625032
Leisegang, Bouic, Menkveld, Henkel: Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort. in Reproductive biology and endocrinology : RB&E 2014
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Human Insulin ELISA Kit for Sandwich ELISA - ABIN649043
Gerbitz et al.: [Pancreatic B cell peptides: kinetic behaviour and concentrations of proinsulin, insulin and C-peptide in plasma and urine, problems of assay methods, clinical significance and literature review ... in Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1981
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Mouse (Murine) Insulin ELISA Kit for Competition ELISA - ABIN415467
Guo, Yu, Li, Liu, Feng, Wang, Meng, Li, Ju, Wang: Impaired neural stem/progenitor cell proliferation in streptozotocin-induced and spontaneous diabetic mice. in Neuroscience research 2010
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Rat (Rattus) Insulin ELISA Kit for Sandwich ELISA - ABIN1979556
Al-Gayyar, Alyoussef, Hamdan, Abbas, Darweish, El-Hawwary: Cod liver oil ameliorates sodium nitrite-induced insulin resistance and degradation of rat hepatic glycogen through inhibition of cAMP/PKA pathway. in Life sciences 2014
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Human Insulin ELISA Kit for Competition ELISA - ABIN1873331
Tiunov, Kustov, Arutiunian, Belyĭ, Gudiev: [Data regarding the toxicology of CO]. in Gigiena truda i professional'nye zabolevaniia 1986
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Cow (Bovine) Insulin ELISA Kit for Sandwich ELISA - ABIN364600
Li, Sun, Yi, Ma, Sun, Zhang, Zhou: Detection of nerve growth factor (NGF) and its specific receptor (TrkA) in ejaculated bovine sperm, and the effects of NGF on sperm function. in Theriogenology 2010
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Human Insulin ELISA Kit for Sandwich ELISA - ABIN2684752
Wang, Zhan, Li, Yu, Liu: Identification and validation co-differentially expressed genes with NAFLD and insulin resistance. in Endocrine 2015
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Upon stratifying the participants into tertiles by the Matsuda index, we observed an inhibitory relationship between the genetic risk score (GRS (show BCL2A1 ELISA Kits)) and insulin secretion in low insulin sensitive but not in high insulin sensitive controls and treatment-naive Type 2 diabetes.
The possibility of using insulin as a biomarker to guide insulin-targeted interventions also should be taken into account
the concentrations of insulin, IGF-1 (show IGF1 ELISA Kits), IGFBP-3 (show IGFBP3 ELISA Kits) and their association with prostate size in patients with BPH (show GLI3 ELISA Kits)
Elevated Unmethylated Insulin DNA Is associated with beta cell death.
These results provide new information on the role of human islet-derived extracellular vesicles in the regulation of insulin expression in differentiating induced pluripotent stem cell clusters.
our experiments reveal an insulin-dependent activation of MCH (show PMCH ELISA Kits) neurons in obesity, which contributes via distinct mechanisms to the manifestation of impaired locomotor activity and insulin resistance.
These data support a role for islet NGF (show NGFB ELISA Kits) in fine-tuning insulin secretion.
Data suggest early peaks in glucagon-like peptide-1 (show GCG ELISA Kits) and glucagon (show GCG ELISA Kits) secretion/blood level together trigger exaggerated insulinotropic response (high insulin secretion/level) to eating and consequent hypoglycaemia in patients with postprandial hypoglycaemia as a postoperative complication following Roux-en-Y gastric bypass for obesity complicated by type 2 diabetes; this retrospective cohort study was conducted in London.
Studies on the susceptibility to aggregation of truncated analogs of insulin amyloidogenic core show three groups of peptides. Truncation of A13-A419 fragment shows that fibrous structures are formed by all peptides bearing (13)H-LeuTyr-OH(14). Propensity to aggregation was found for (16)H-TyrLeu-OH(17) B12 (show NDUFB3 ELISA Kits)-B17 (show NDUFB6 ELISA Kits) fragment.
Insulin and PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling are essential for RNase 7 (show RNASE7 ELISA Kits) expression and increased infection risks in diabetic patients may be secondary to suppressed RNase 7 (show RNASE7 ELISA Kits) production.
Study used well-tempered bias exchange metadynamics simulations to determine the equilibrium ensembles of an insulin molecule under amyloidogenic conditions of low pH and high temperature. The folded state of a single insulin molecule was shown to be the most stable, longest-lived state even under amyloidogenic conditions.
The findings are consistent with previous studies that indicate a link between Na,K-ATPase (show ATP1A1 ELISA Kits) activity and SFK signaling.
PTPLAD1 (show PTPLAD1 ELISA Kits) and AMPK (show PRKAA1 ELISA Kits) are rapidly compartmentalized within the plasma membrane (PM) and Golgi/endosome fractions after insulin stimulation and that ATIC (show ATIC ELISA Kits) later accumulates in the Golgi/endosome fraction.
Pdx-1 (show PDX1 ELISA Kits), MafA (show MAFA ELISA Kits) and NeuroD1 (show NEUROD1 ELISA Kits) bind to the A, C and E elements in the insulin promoter and regulate the transcriptional activity of the insulin promoter.
The interplay of the adiponectin system, TNFalpha (show TNF ELISA Kits) and insulin at a transcriptional level and, their effects on the adipogenic transcription factor PPARgamma (show PPARG ELISA Kits), as well as on the activation of main insulin signaling pathways, is reported.
Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.
Exposing the hydrophobic core of insulin can induce the increase of amyloidogenicity and formation of higher-order polymerized fibrils, which is less toxic to membranes.
Data suggest that a mutation in INS (C94Y) results a transgenic disease model for the investigation of permanent neonatal diabetes.
The results show that modulation of plasma insulin levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I (show IGF1 ELISA Kits) levels are less easily modified.
insulin increased GCLc (show GCLC ELISA Kits) promoter activity, which required a prerequisite increase or decrease in medium glucose
Insulin signaling role in skeletal muscle atrophy and autophagy in in transition and postpartum period
Differences between human and bovine insulin kinetics under shear
increased sensitivity to glucose clearance and skeletal muscle insulin signaling during dietary restriction
Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (show LEP ELISA Kits)-NPY (show NPY ELISA Kits) and insulin signaling pathways.
Raman spectra of amino acids by Density Functional Theory method have been calculated. Experimental Raman spectra of insulin has been done. The simulated Raman spectrum of insulin is obtained from amino acid spectrum.
Contains Binding kinetics for insulin binding
Using synchrotron radiation (SR), the crystal structures of T6 bovine insulin complexed with Ni(2 (show VMP1 ELISA Kits)+) and Cu(2+) were solved to 1.50 and 1.45 A resolution, respectively.
The present study examined the effect of insulin-mediated activation of the mammalian target of rapamycin (show FRAP1 ELISA Kits) complex 1 (MTORC1) signaling network on the proliferation of primary culture of theca-interstitial (T-I) cells.
In-situ spectroscopic investigation of ultrasonic assisted unfolding and aggregation of insulin.
insulin supports early initiation of the mesodermal factor Brachyury (show TBX1 ELISA Kits) and the signalling molecules Wnt3a (show WNT3A ELISA Kits) and Wnt4 (show WNT4 ELISA Kits) as well as the progression of mesoderm formation
Data show that type 1 diabetic blastocyst did not express insulin mRNA.
cTAGE5 (show CTAGE5 ELISA Kits) deletion in pancreatic beta cells impairs proinsulin trafficking and insulin biogenesis in mice.
These results suggest that prolonged exposure to hyperglycemia in the Ins2(Akita+/-) mice leads to progressive testicular disruption mediated by testicular activin (show Actbeta ELISA Kits) activity, rather than hormonal dysregulation.
report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining region Y-box 2 (Sox2 (show SOX2 ELISA Kits)) is a mediator of excess BMP signaling that results in activation of EndMTs and increased vascular calcification
Transplantation of transduced hematopoietic stem cells (HSCs) expressing proinsulin II prevents diabetes development.
Wnt3a increased the expression of NeuroD1 and Ins2 in the hypothalamus.
Data suggest that resveratrol acts on differentiating preadipocytes by inhibiting insulin signaling, mitochondrial biogenesis, and lipogenesis.
have characterized the distinctive sex-specific phenotypes exhibited by the ApoE(-/-):Ins2(+/Akita) mouse model and present evidence for the action of sex hormones on pancreatic beta-cell function
Data indicate that Src homology-2 domain containing protein B (SHB) deficiency causes a chronic increase in beta-cell focal adhesion kinase (FAK) activity that perturbs the normal insulin secretory characteristics of beta-cells.
Mouse Ins2 and Ins1 promoters were transiently activated in mouse fetal hepatocytes of embryonic days 13.5 and 16.5, respectively.
Data indicate that insulin/incomplete Freund's adjuvant (IFA) does not prevent but induces diabetes in RIP-CD80GP transgenic mice.
Temporal and spatial expression of two insulin genes (insa and insab) during early developmental stages.
These findings suggest that GHRL (show GHRL ELISA Kits) regulates INS synthesis by mediating its action on growth hormone secretagogue-receptor (show GHSR ELISA Kits) in the central nervous system and partly involved in carbohydrate-glycogen (show GYS2 ELISA Kits) metabolism.
Our results indicate that in adult tilapia insulin expression is not restricted to the endocrine pancreatic cells, but also occurs in endocrine cells of the pituitary gland and in the neuronal cells of the brain.
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.