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Browse our anti-PRKACA (PRKACA) Antibodies

Full name:
anti-Protein Kinase A, alpha Antibodies (PRKACA)
On are 73 Protein Kinase A, alpha (PRKACA) Antibodies from 12 different suppliers available. Additionally we are shipping PRKACA Proteins (17) and PRKACA Kits (6) and many more products for this protein. A total of 100 PRKACA products are currently listed.
list all antibodies Gene Name GeneID UniProt
PRKACA 18747 P05132
PRKACA 5566 P17612
PRKACA 25636  

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Most Popular Reactivities for anti-PRKACA (PRKACA) Antibodies

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anti-Mouse (Murine) PRKACA Antibodies:

anti-Human PRKACA Antibodies:

anti-Rat (Rattus) PRKACA Antibodies:

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Top referenced anti-PRKACA Antibodies

  1. Human Polyclonal PRKACA Primary Antibody for EIA, IHC (p) - ABIN359056 : Tateyama, Rivolta, Clancy, Kass: Modulation of cardiac sodium channel gating by protein kinase A can be altered by disease-linked mutation. in The Journal of biological chemistry 2003 (PubMed)
    Show all 5 references for ABIN359056

  2. Human Monoclonal PRKACA Primary Antibody for WB - ABIN238374 : Beebe, Oyen, Sandberg, Frøysa, Hansson, Jahnsen: Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase. in Molecular endocrinology (Baltimore, Md.) 1990 (PubMed)
    Show all 5 references for ABIN238374

  3. Human Polyclonal PRKACA Primary Antibody for EIA, WB - ABIN453298 : Sugiyama, Chen, Hunter, Taffs, Sitkovsky: The dual role of the cAMP-dependent protein kinase C alpha subunit in T-cell receptor-triggered T-lymphocytes effector functions. in The Journal of biological chemistry 1993 (PubMed)

  4. Human Polyclonal PRKACA Primary Antibody for ELISA, WB - ABIN562366 : Adachi, Kano, Saido, Murata: Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion. in Genes to cells : devoted to molecular & cellular mechanisms 2009 (PubMed)

More Antibodies against PRKACA Interaction Partners

Mouse (Murine) Protein Kinase A, alpha (PRKACA) interaction partners

  1. PKA phosphorylates the ATPase inhibitory factor 1 (show ATPIF1 Antibodies) and inactivates its capacity to bind and inhibit the mitochondrial H(+)-ATP synthase.

  2. Data suggest PRKAR1A (show PRKAR1A Antibodies) contains two structurally homologous cAMP-binding domains that exhibit marked differences in dynamic profiles in activation/inhibition of Prkaca; conservation of structure does not necessarily imply conservation of dynamics.

  3. Data (including data from studies in transgenic mice) suggest that constitutive activation of Prkaca in osteoblasts is sufficient to increase bone mass, favorably modify bone architecture, and improve mechanical properties of bone.

  4. Lin28a (show LIN28A Antibodies) protects against DCM through PKA/ROCK2 (show ROCK2 Antibodies) dependent pathway.

  5. We postulate that this novel interaction linking MVI with the PKA pathway could be important for targeting AKAP9 (show AKAP9 Antibodies)-PKA complex within cells and/or providing PKA to phosphorylate MVI tail domain.

  6. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

  7. Data suggest that investigation of cAMP-dependent protein kinase A (PKA) and its signaling in D2 receptor (show DRD2 Antibodies)-expressing indirect pathway medium-sized spiny neurons (iMSNs) would better understand the mechanisms underlying psychiatric disorders.

  8. This study investigates the affinity between the protein kinase PKA and peptide substrates derived from kemptide using molecular dynamics simulations.

  9. Our results provide evidence that cSrc is activated downstream of PKA and that inhibition of its activity blocks the capacitation-induced hyperpolarization of the sperm plasma membrane .

  10. Collectively, our studies highlighted that the CuB-induced actin aggregation and cofilin (show CFL1 Antibodies)-actin rod formation was mediated via the Ga13/RhoA (show RHOA Antibodies)/PKA/VASP (show VASP Antibodies) pathway.

Human Protein Kinase A, alpha (PRKACA) interaction partners

  1. Data show that activated PKA phosphorylates the 19S subunit, Rpn6/PSMD11 (show PSMD11 Antibodies) (regulatory particle non-ATPase 6 (show MT-ATP6 Antibodies)/proteasome subunit D11) at Ser14.

  2. PKA phosphorylates the ATPase inhibitory factor 1 (show ATPIF1 Antibodies) and inactivates its capacity to bind and inhibit the mitochondrial H(+)-ATP synthase.

  3. DNAJB1 (show DNAJB1 Antibodies)-PRKACA was evaluated as a key driver of fibrolamellar carcinoma and as a candidate therapeutic target

  4. No somatic mutations were observed in PRKACA in a cohort of GH-secreting pituitary adenomas.

  5. Kapbeta2 interacts with ULK2 (show ULK2 Antibodies) through ULK2 (show ULK2 Antibodies)'s putative PY-NLS (show ALDH1A2 Antibodies) motif, and facilitates transport from the cytoplasm to the nucleus, depending on its Ser1027 residue phosphorylation by PKA, thereby reducing autophagic activity.

  6. ITM2A (show ITM2A Antibodies) expression is positively regulated by PKA-CREB (show CREB1 Antibodies) signaling and ITM2A (show ITM2A Antibodies) expression interferes with autophagic flux by interacting with vacuolar ATPase (show DNAH8 Antibodies).

  7. Akt (show AKT1 Antibodies) and PKA phosphorylated KLHL3 (show KLHL3 Antibodies) at S433, and phosphorylation of KLHL3 (show KLHL3 Antibodies) by PKA inhibited WNK4 (show WNK4 Antibodies) degradation.

  8. Data indicate that protein kinase A (PKA) phosphorylates only serine-253 amino acid on activator of G-protein signaling 1 (show RASD1 Antibodies) protein Dexras1 (RASD1 (show RASD1 Antibodies)).

  9. PKA compartmentalization via AKAP220 (show AKAP11 Antibodies) and AKAP12 (show AKAP12 Antibodies) contributes to endothelial barrier regulation.

  10. Leu206Arg and Leu199_Cys200insTrp mutations in PRKACA impair its association with PRKAR2B (show PRKAR2B Antibodies) and PRKAR1A (show PRKAR1A Antibodies).

Pig (Porcine) Protein Kinase A, alpha (PRKACA) interaction partners

  1. ceramide as a potent physiological modulator of the Na(+)-ATPase (show DNAH8 Antibodies), participating in a regulatory network in kidney cells and counteracting the stimulatory effect of PKA via PKCzeta (show PRKCZ Antibodies)

  2. we demonstrate that PKA, PKC (show FYN Antibodies) and PI3K pathways crosstalk in porcine male germ cells to crucially regulate GSK3A (show GSK3a Antibodies) phosphorylation which subsequently controls cell motility.

Cow (Bovine) Protein Kinase A, alpha (PRKACA) interaction partners

  1. Data indicate that mitochondrial cAMP-dependent protein kinase (PKA) activity is regulated by the protease calpain.

  2. structural basis of selectivity for protein kinase A in complex with Rho-kinase (show ROCK1 Antibodies) inhibitors by x-ray crystallography

  3. Purification and characterisation of protein kinase catalytic subunit (PKAcat) from bovine lens.

PRKACA Antigen Profile

Antigen Summary

Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion transport, and gene transcription. The PKA holoenzyme is composed of 2 regulatory and 2 catalytic subunits and dissociates from the regulatory subunits upon binding of cAMP.

Alternative names and synonyms associated with PRKACA

  • protein kinase, cAMP dependent, catalytic, alpha (Prkaca) antibody
  • protein kinase, cAMP-dependent, catalytic, alpha (PRKACA) antibody
  • protein kinase, cAMP-dependent, catalytic, alpha (Prkaca) antibody
  • protein kinase, cAMP-dependent, regulatory, type I, beta (PRKAR1B) antibody
  • Calpha antibody
  • Cs-PKA antibody
  • PKA antibody
  • PKACA antibody
  • PKCA1 antibody
  • PKCD antibody
  • PRKAR1 antibody

Protein level used designations for PRKACA

PKA C-alpha , cAMP-dependent protein kinase catalytic subunit alpha , sperm cAMP-dependent protein kinase catalytic subunit , protein kinase A catalytic subunit , protein kinase, cAMP-dependent, catalytic, alpha , C-alpha subunit , protein kinase A , cAMP-dependent protein kinase catalytic subunit C alpha , protein kinase A alpha , cAMP-dependent protein kinase type I-beta regulatory subunit

18747 Mus musculus
5566 Homo sapiens
397652 Sus scrofa
282322 Bos taurus
443094 Ovis aries
25636 Rattus norvegicus
403556 Canis lupus familiaris
5575 Homo sapiens
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