Browse our SQSTM1 (SQSTM1) ELISA Kits

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Sequestosome 1 ELISA Kits (SQSTM1)
On www.antibodies-online.com are 8 Sequestosome 1 (SQSTM1) ELISA Kits from 5 different suppliers available. Additionally we are shipping SQSTM1 Antibodies (307) and SQSTM1 Proteins (14) and many more products for this protein. A total of 344 SQSTM1 products are currently listed.
Synonyms:
A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, sqstm1, STAP, zgc:85784, ZIP, ZIP3
list all ELISA KIts Gene Name GeneID UniProt
SQSTM1 8878 Q13501
SQSTM1 18412 Q64337
SQSTM1 113894 O08623

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SQSTM1 (SQSTM1) ELISA Kits by Reactivity

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More ELISA Kits for SQSTM1 Interaction Partners

Human Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (show FAM126A ELISA Kits)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. necessary for retinal pigmented epithelial cytoprotection under oxidative stress; NFkappaB p65 activity may be critical upstream initiator of p62 expression in retinal pigmented epithelial cells under oxidative stress

  3. p62/SQSTM1, which accumulates in autophagy-defective cells, directly binds to and inhibits nuclear RNF168 (show RNF168 ELISA Kits), an E3 ligase essential for histone H2A ubiquitination and DNA damage responses. As a result, DNA repair proteins such as BRCA1, RAP80 (show UIMC1 ELISA Kits), and Rad51 (show RAD51 ELISA Kits) cannot be recruited to the sites of DNA double-strand breaks (DSBs), which impairs DSB repair.

  4. propose that the interplay between LRRK2 (show LRRK2 ELISA Kits) and p62 (show GTF2H1 ELISA Kits) may contribute to the pathophysiological function and homeostasis of LRRK2 (show LRRK2 ELISA Kits) protein

  5. Frontotemporal dementia -linked mutations in gene p62/SQSTM1 encoding autophagy adaptor proteins , indicate that impaired autophagy might cause Frontotemporal dementia.

  6. These data suggest that SQSTM1 mutations are not a common cause of normal tension glaucoma.

  7. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  8. siRNA-mediated knockdown of p62 clearly increased the efficiency of transfection of murine embryonic stem (mES) cells and human HeLa cells. These data indicate that p62 acts as a key regulator of gene delivery.

  9. These studies suggest that p62 is involved in the genesis of nuclear factor kappaB-induced proinflammatory and prolabor mediators.

  10. In this review, we discuss p62-mediated signaling pathways and their roles in liver pathophysiology, especially nonalcoholic steatohepatitis and hepatocellular carcinoma

Mouse (Murine) Sequestosome 1 (SQSTM1) interaction partners

  1. Authors found that p62/SQSTM1, a protein upregulated in liver parenchymal cells but downregulated in HCC (show FAM126A ELISA Kits)-associated HSCs, negatively controls hepatic stellate cells activation.

  2. SQSTM1 or damaged proteins may be transported from the nose to the brain. These findings strongly implicate widespread protein damage in the etiology of flavorings-related lung disease.

  3. Promoting amino acid sensitivity of the mTOR pathway is dependent on p62 accumulation by inhibition of autophagy and this process plays an important role in the hepatic differentiation of stem/progenitor cells.

  4. role of p62 (show GTF2H1 ELISA Kits) in MDB (show ABR ELISA Kits) maturation and stability

  5. two ALS-linked factors, SQSTM1 and ALS2 (show ALS2 ELISA Kits), have distinct but additive protective roles against mutant SOD1 (show SOD1 ELISA Kits)-mediated toxicity by modulating neuronal proteostasis possibly through the autophagy-endolysosomal system.

  6. These results demonstrated that p62-dependent mitophagy has an immunosuppressive role to innate immune response and might serve as a potential immunomodulatory target for inflammation-associated diseases.

  7. results indicate that autophagy is important for the removal of excess Endoplasmic Reticulum and hepatic CYP enzymes in mouse livers, a process associated with the autophagy receptor protein p62.

  8. p62 (show GTF2H1 ELISA Kits) reduces UVB-induced apoptosis by modulating intrinsic apoptotic signaling through Src (show SRC ELISA Kits) phosphorylation.

  9. Our results indicate that JEV replication is impaired in p62-deficient MEFs, suggesting that p62 positively regulates JEV replication in host cells.

  10. Results demonstrate that p62 (show GTF2H1 ELISA Kits) facilitates activation of NRF2 (show NFE2L2 ELISA Kits) and mTORC1 and is essential for hepatocellular carcinomas (HCC (show FAM126A ELISA Kits)) initiation.

Zebrafish Sequestosome 1 (SQSTM1) interaction partners

  1. Loss-of-function of SQSTM1 may cause phenotypic features characterized by locomotor deficits and motor neuron axonal defects that are associated with a misregulation of autophagic processes.

SQSTM1 Antigen Profile

Antigen Summary

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Alternative names and synonyms associated with SQSTM1

  • sequestosome 1 (SQSTM1) Elisa Kit
  • sequestosome 1 (LOC100342157) Elisa Kit
  • sqstm1 protein (sqstm1) Elisa Kit
  • sequestosome 1 (Sqstm1) Elisa Kit
  • sequestosome 1 (sqstm1) Elisa Kit
  • A170 Elisa Kit
  • MGC79491 Elisa Kit
  • OSF-6 Elisa Kit
  • Osi Elisa Kit
  • OSIL Elisa Kit
  • p60 Elisa Kit
  • p62 Elisa Kit
  • p62B Elisa Kit
  • PDB3 Elisa Kit
  • sb:cb621 Elisa Kit
  • sqstm1 Elisa Kit
  • STAP Elisa Kit
  • zgc:85784 Elisa Kit
  • ZIP Elisa Kit
  • ZIP3 Elisa Kit

Protein level used designations for Sequestosome 1 (SQSTM1) ELISA Kits

sequestosome 1 , sequestosome-1 , sequestosome-1-like , sqstm1 protein , EBI3-associated protein of 60 kDa , EBI3-associated protein p60 , EBIAP , oxidative stress induced like , phosphotyrosine independent ligand for the Lck SH2 domain p62 , phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa , ubiquitin-binding protein p62 , STONE14 , oxidative stress induced , PKC-zeta-interacting protein , protein kinase C-zeta-interacting protein

GENE ID SPECIES
462333 Pan troglodytes
705481 Macaca mulatta
770805 Gallus gallus
100135450 Ovis aries
100342157 Oryctolagus cuniculus
100385650 Callithrix jacchus
493277 Xenopus (Silurana) tropicalis
100067231 Equus caballus
8878 Homo sapiens
18412 Mus musculus
113894 Rattus norvegicus
406452 Danio rerio
379610 Xenopus laevis
338045 Bos taurus
481459 Canis lupus familiaris
100172461 Pongo abelii
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