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SQSTM1 Products

(Sequestosome 1 (SQSTM1))

Categories

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009].

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Featured SQSTM1 Categories

SQSTM1 Antibodies

High quality antibodies with extensive validation data.

SQSTM1 ELISA Kits

Reliable ELISA kits for a wide range of species.

SQSTM1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SQSTM1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Bee, Cow, Human, Mosquito, Mouse, Rat
Application ICC, FACS, IF, IP, IHC (p), WB
Validations
  • (13)
  • (23)
Cat. No. ABIN2854836
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IF, IHC (p), WB
Validations
  • (22)
  • (6)
Cat. No. ABIN388979
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (fro), IHC (p), WB
Validations
  • (5)
  • (6)
Cat. No. ABIN3043937
Quantity 100 μg
Datasheet Datasheet

Recommended SQSTM1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970104
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959370
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6959371
Quantity 96 tests
Datasheet Datasheet

Recommended SQSTM1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095565
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135590
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1321293
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our SQSTM1 products

Liu, Jiang, Wu, Wu, Wu, Zhao, Sun, Huang, Li, Sheng, Barbier, Cintrat, Gillet, Su: "Antiviral Effects of ABMA and DABMA against Influenza Virus In Vitro and In Vivo via Regulating the Endolysosomal Pathway and Autophagy." in: , Vol. 23, Issue 7, (2022) (PubMed).

Deng, Liu, Wang, Wei, Peng: "GPA Peptide-Induced Nur77 Localization at Mitochondria Inhibits Inflammation and Oxidative Stress through Activating Autophagy in the Intestine." in: Oxidative medicine and cellular longevity, Vol. 2020, pp. 4964202, (2021) (PubMed).

Jia, Li, Liu, Si, Jin, Wang, Ma, Chu: "Based on Activation of p62-Keap1-Nrf2 Pathway, Hesperidin Protects Arsenic-Trioxide-Induced Cardiotoxicity in Mice." in: Frontiers in pharmacology, Vol. 12, pp. 758670, (2021) (PubMed).

Chen, Li, Yuan, Gu, Zhang, Fan, Wu, Xiong, Yang: "α-Solanine Causes Cellular Dysfunction of Human Trophoblast Cells via Apoptosis and Autophagy." in: Toxins, Vol. 13, Issue 1, (2021) (PubMed).

Cho, Lee, Bae, Chou: "Activation of tumor-promoting pathways implicated in hepatocellular adenoma/carcinoma, a long-term complication of glycogen storage disease type Ia." in: Biochemical and biophysical research communications, Vol. 522, Issue 1, pp. 1-7, (2020) (PubMed).

Brewer, Herrera, Philipp, Sosna, Reyes-Ruiz, Glabe: "Age-Related Intraneuronal Aggregation of Amyloid-β in Endosomes, Mitochondria, Autophagosomes, and Lysosomes." in: Journal of Alzheimer's disease : JAD, Vol. 73, Issue 1, pp. 229-246, (2020) (PubMed).

Cheung, Hsu, Lin, Chen, Wang, Huang, Juan: "ZNF322A-mediated protein phosphorylation induces autophagosome formation through modulation of IRS1-AKT glucose uptake and HSP-elicited UPR in lung cancer." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 75, (2020) (PubMed).

Chou, Lin, Dzhagalov, Chen, Lin, Lin, Chen, Chen, Fu: "Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy." in: Scientific reports, Vol. 10, Issue 1, pp. 8422, (2020) (PubMed).

Jensen, Schuldi, McAvoy, Russell, Boehringer, Curran, Krishnamurthy, Wen, Westergard, Ma, Haeusler, Edbauer, Pasinelli, Trotti: "Synaptic dysfunction induced by glycine-alanine dipeptides in C9orf72-ALS/FTD is rescued by SV2 replenishment." in: EMBO molecular medicine, Vol. 12, Issue 5, pp. e10722, (2020) (PubMed).

Martello, Lauriola, Mellis, Parish, Dawson, Imrie, Vidmar, Gammoh, Mitić, Brittan, Mills, Carragher, DArca, Caporali: "Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy." in: EMBO reports, Vol. 21, Issue 7, pp. e48192, (2020) (PubMed).

Synonyms and alternative names related to SQSTM1

sequestosome 1 (SQSTM1), sequestosome 1 (sqstm1), sequestosome 1 (Sqstm1), sequestosome 1 L homeolog (sqstm1.L), A170, MGC79491, OSF-6, Osi, OSIL, p60, p62, p62B, PDB3, sb:cb621, SQSTM1, sqstm1, STAP, zgc:85784, ZIP, ZIP3

Protein level used designations for SQSTM1

  • sequestosome 1
  • sequestosome-1
  • sequestosome-1-like
  • sqstm1 protein
  • EBI3-associated protein of 60 kDa
  • EBI3-associated protein p60
  • EBIAP
  • oxidative stress induced like
  • phosphotyrosine independent ligand for the Lck SH2 domain p62
  • phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa
  • ubiquitin-binding protein p62
  • STONE14
  • oxidative stress induced
  • PKC-zeta-interacting protein
  • protein kinase C-zeta-interacting protein
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