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Browse our anti-NCOR2 (NCOR2) Antibodies

Full name:
anti-Nuclear Receptor Co-Repressor 2 Antibodies (NCOR2)
On are 54 Nuclear Receptor Co-Repressor 2 (NCOR2) Antibodies from 17 different suppliers available. Additionally we are shipping NCOR2 Kits (5) and and many more products for this protein. A total of 64 NCOR2 products are currently listed.
list all antibodies Gene Name GeneID UniProt
NCOR2 20602 Q9WU42
NCOR2 360801  
NCOR2 9612 Q9Y618

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Most Popular Reactivities for anti-NCOR2 (NCOR2) Antibodies

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anti-Mouse (Murine) NCOR2 Antibodies:

anti-Rat (Rattus) NCOR2 Antibodies:

anti-Human NCOR2 Antibodies:

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Top referenced anti-NCOR2 Antibodies

  1. Human Monoclonal NCOR2 Primary Antibody for IF, WB - ABIN968510 : Chen, Evans: A transcriptional co-repressor that interacts with nuclear hormone receptors. in Nature 1995 (PubMed)
    Show all 4 references for ABIN968510

  2. Human Polyclonal NCOR2 Primary Antibody for WB - ABIN2779658 : Keeton, Brown: Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. in Molecular endocrinology (Baltimore, Md.) 2005 (PubMed)

  3. Human Polyclonal NCOR2 Primary Antibody for ELISA, WB - ABIN564153 : Zhang, Gong, Lau, Yang, Wong, Cheung, Tsang, Chan, Khoo: SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ER? transcriptional activity. in Cancer research 2013 (PubMed)

More Antibodies against NCOR2 Interaction Partners

Mouse (Murine) Nuclear Receptor Co-Repressor 2 (NCOR2) interaction partners

  1. demonstrate that the binding of HDAC3 (show HDAC3 Antibodies) to IR nGREs in vivo is mediated through interaction with SMRT/NCoR1 (show NCOR1 Antibodies)

  2. GR SUMOylation site is mandatory for the formation of a GR-small ubiquitin-related modifiers (SUMOs)-SMRT/NCoR1 (show NCOR1 Antibodies)-HDAC3 (show HDAC3 Antibodies) repressing complex, which is indispensable for NF-kappaB (show NFKB1 Antibodies)/AP1 (show JUN Antibodies)-mediated GC-induced tethered indirect transrepression in vitro

  3. changes in dietary components can consistently, if moderately, modulate the total transcript levels and the mRNA splicing of NCoR (show NCOR1 Antibodies) and SMRT in both cultured cells and intact mice.

  4. SMRT regulates glucocorticoid action in adipocytes.

  5. While silencing mediator of retinoid and thyroid hormone receptor (show THRA Antibodies) played little role in TH-regulated pathways, when disrupted in combination with nuclear receptor corepressor, it greatly accentuated the synthesis and storage of hepatic lipid

  6. HDAC3 (show HDAC3 Antibodies) enzyme activity is undetectable in mice bearing point mutations in the deacetylase-activating domain of both NCOR1 (show NCOR1 Antibodies) and SMRT.

  7. These results reveal that Bcl6 (show BCL6 Antibodies)-SMRT/NCoR (show NCOR1 Antibodies) complexes constrain immune responses and contribute to the prevention of atherosclerosis.

  8. SMRT is an adipogenic gatekeeper as it directly fine-tunes transcription of pro- and antiadipogenic genes.

  9. miR (show MLXIP Antibodies)-184 downregulated nuclear receptor corepressor 2 (Ncor2) by targeting its 3' untranslated region through inhibiting NCOR2 protein translation

  10. Data show that knock-in mutations of the nuclear co-repressor SMRT in C57BL/6 mice produces a previously unidentified respiratory distress syndrome caused by prematurity of the type I pneumocyte.

Human Nuclear Receptor Co-Repressor 2 (NCOR2) interaction partners

  1. this study identifies NCOR2 as a new gene for FVC, indicating the importance of further research into the role of vitamin A intake/supplementation and its interactions with related genes in the regulation of FVC.

  2. Molecular basis for the specific interactions between HDAC4 (show HDAC4 Antibodies) and the SMRT corepressor.

  3. SNPs in Notch (show NOTCH1 Antibodies) pathway genes may be predictors of cutaneous melanoma disease-specific survival.

  4. Significant methylation changes in the SLC23A2 (show SLC23A2 Antibodies) and NCOR2 regulatory regions.

  5. A repeated peptide motif present in both SMRT and NCoR is sufficient to mediate specific interaction, with micromolar affinity, with all the Class IIa Histone Deacetylases (HDACs 4, 5, 7, and 9).

  6. SMRT enhances cell growth of estrogen receptor-alpha (show ESR1 Antibodies)-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis.

  7. Phosphorylation of the CK2 (show CSNK2A1 Antibodies) site on SMRT significantly increased affinity for SHARP.

  8. model where p53 (show TP53 Antibodies) binding to the SMRT deacetylase activation domain (DAD) limits HDAC3 (show HDAC3 Antibodies) interaction with this coregulator, thereby facilitating SMRT coactivation of p53 (show TP53 Antibodies)-dependent gene expression

  9. SMRT is responsible for basal repression of Wip1 (show PPM1D Antibodies),a phosphatase that de-phosphorylates and inactivates Chk2 (show CHEK2 Antibodies), thus affecting a feedback loop responsible for licensing the correct timing of Chk2 (show CHEK2 Antibodies) activation and the proper execution of the DNA repair process.

  10. a model in which TNFalpha (show TNF Antibodies)-induced beta-TrCP1 (show BTRC Antibodies) accumulation promotes SMRT degradation and the subsequent induction of proinflammatory gene expression.

NCOR2 Antigen Profile

Antigen Summary

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with NCOR2

  • nuclear receptor corepressor 2 (NCOR2) antibody
  • nuclear receptor co-repressor 2 (Ncor2) antibody
  • CTG26 antibody
  • N-CoR antibody
  • N-CoR2 antibody
  • SMAP270 antibody
  • SMRT antibody
  • SMRTE antibody
  • SMRTE-tau antibody
  • TNRC14 antibody
  • TRAC antibody
  • TRAC-1 antibody
  • TRAC1 antibody

Protein level used designations for NCOR2

nuclear receptor co-repressor 2 , N-CoR2 , T3 receptor-associating factor , TRAC , nuclear receptor corepressor 2 , silencing mediator of retinoic acid and thyroid hormone receptor , silencing mediator of retinoid acid and thyroid hormone receptor , thyroid-, retinoic-acid-receptor-associated corepressor , CTG repeat protein 26 , silencing mediator for retinoid and thyroid hormone receptors

416815 Gallus gallus
20602 Mus musculus
360801 Rattus norvegicus
9612 Homo sapiens
486242 Canis lupus familiaris
538549 Bos taurus
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