Browse our anti-NCOR2 (NCOR2) Antibodies

Full name:
anti-Nuclear Receptor Co-Repressor 2 Antibodies (NCOR2)
On www.antibodies-online.com are 75 Nuclear Receptor Co-Repressor 2 (NCOR2) Antibodies from 18 different suppliers available. Additionally we are shipping NCOR2 Kits (9) and and many more products for this protein. A total of 89 NCOR2 products are currently listed.
Synonyms:
ctg26, gb:be017685, N-CoR, N-CoR2, NCOR2, si:bz71m17.2, SMAP270, smrt, smrte, smrte-tau, tnrc14, TRAC, trac-1, trac1
list all antibodies Gene Name GeneID UniProt
NCOR2 9612 Q9Y618
NCOR2 360801  
NCOR2 20602 Q9WU42

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anti-Human NCOR2 Antibodies:

anti-Rat (Rattus) NCOR2 Antibodies:

anti-Mouse (Murine) NCOR2 Antibodies:

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Top referenced anti-NCOR2 Antibodies

  1. Human Monoclonal NCOR2 Primary Antibody for IF, WB - ABIN968510 : Chen, Evans: A transcriptional co-repressor that interacts with nuclear hormone receptors. in Nature 1995 (PubMed)
    Show all 4 references for 968510

  2. Cow (Bovine) Polyclonal NCOR2 Primary Antibody for WB - ABIN2779658 : Keeton, Brown: Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. in Molecular endocrinology (Baltimore, Md.) 2005 (PubMed)

  3. Human Polyclonal NCOR2 Primary Antibody for ELISA, WB - ABIN564153 : Zhang, Gong, Lau, Yang, Wong, Cheung, Tsang, Chan, Khoo: SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ER? transcriptional activity. in Cancer research 2013 (PubMed)

  4. Human Polyclonal NCOR2 Primary Antibody for IP, PLA - ABIN188817 : Zhou, Li, Hu, Gong, Drescher, Chen: miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene. in PLoS ONE 2012 (PubMed)

  5. Human Monoclonal NCOR2 Primary Antibody for ChIP, IHC (fro) - ABIN266935 : Catalano, Mauro, Bonofiglio, Pellegrino, Qi, Rizza, Vizza, Bossi, Andò: In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer. in The American journal of pathology 2011 (PubMed)

More Antibodies against NCOR2 Interaction Partners

Human Nuclear Receptor Co-Repressor 2 (NCOR2) interaction partners

  1. The mechanism of IL-6-induced AR activation is mediated through enhancing AR-SRC-1 interaction and inhibiting AR-SMRT interaction.

  2. IL-6-mediated AR antagonism induced by cypermethrin is related to repress the recruitment of co-regulators SRC-1 and SMRT to the AR in a ligand-independent manner

  3. this study identifies NCOR2 as a new gene for FVC, indicating the importance of further research into the role of vitamin A intake/supplementation and its interactions with related genes in the regulation of FVC.

  4. Molecular basis for the specific interactions between HDAC4 and the SMRT corepressor.

  5. SNPs in Notch (show NOTCH1 Antibodies) pathway genes may be predictors of cutaneous melanoma disease-specific survival.

  6. Significant methylation changes in the SLC23A2 and NCOR2 regulatory regions.

  7. A repeated peptide motif present in both SMRT and NCoR is sufficient to mediate specific interaction, with micromolar affinity, with all the Class IIa Histone Deacetylases (HDACs 4, 5, 7, and 9).

  8. SMRT enhances cell growth of estrogen receptor-alpha (show ESR1 Antibodies)-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis.

  9. Phosphorylation of the CK2 site on SMRT significantly increased affinity for SHARP.

  10. model where p53 (show TP53 Antibodies) binding to the SMRT deacetylase activation domain (DAD) limits HDAC3 (show HDAC3 Antibodies) interaction with this coregulator, thereby facilitating SMRT coactivation of p53 (show TP53 Antibodies)-dependent gene expression

Mouse (Murine) Nuclear Receptor Co-Repressor 2 (NCOR2) interaction partners

  1. Both the acetylation and SUMOylation status of the PXR protein is affected by its ability to associate with the lysine de-acetylating enzyme HDAC3 in a complex with SMRT.

  2. These studies support a model in which NCOR1 (show NCOR1 Antibodies)/2 mediates direct Retinoic acid-dependent repression of Fgf8 (show FGF8 Antibodies) in caudal (show CAD Antibodies) progenitors in order to control somitogenesis.

  3. demonstrate that the binding of HDAC3 (show HDAC3 Antibodies) to IR nGREs in vivo is mediated through interaction with SMRT/NCoR1 (show NCOR1 Antibodies)

  4. GR SUMOylation site is mandatory for the formation of a GR-small ubiquitin-related modifiers (SUMOs)-SMRT/NCoR1 (show NCOR1 Antibodies)-HDAC3 (show HDAC3 Antibodies) repressing complex, which is indispensable for NF-kappaB (show NFKB1 Antibodies)/AP1 (show JUN Antibodies)-mediated GC-induced tethered indirect transrepression in vitro

  5. changes in dietary components can consistently, if moderately, modulate the total transcript levels and the mRNA splicing of NCoR and SMRT in both cultured cells and intact mice.

  6. SMRT regulates glucocorticoid action in adipocytes.

  7. While silencing mediator of retinoid and thyroid hormone receptor (show THRA Antibodies) played little role in TH-regulated pathways, when disrupted in combination with nuclear receptor corepressor, it greatly accentuated the synthesis and storage of hepatic lipid

  8. HDAC3 enzyme activity is undetectable in mice bearing point mutations in the deacetylase-activating domain of both NCOR1 and SMRT.

  9. These results reveal that Bcl6 (show BCL6 Antibodies)-SMRT/NCoR (show NCOR1 Antibodies) complexes constrain immune responses and contribute to the prevention of atherosclerosis.

  10. SMRT is an adipogenic gatekeeper as it directly fine-tunes transcription of pro- and antiadipogenic genes.

Zebrafish Nuclear Receptor Co-Repressor 2 (NCOR2) interaction partners

  1. Ncor1 and Ncor2 play essential but distinct roles in zebrafish primitive myelopoiesis

  2. A novel regulatory mechanism for Ncor2 through Fos-Vegfd-Notch signaling cascade during hematopoietic stem cell development in zebrafish embryos.

  3. rar-ncor2 corepressor complex may be part of an embryonic, epigenetic switch that keeps retinoic acid responsive genes off before retinoic becomes available to the embryo

NCOR2 Antigen Profile

Antigen Summary

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with NCOR2

  • nuclear receptor corepressor 2 (NCOR2) antibody
  • nuclear receptor co-repressor 2 (Ncor2) antibody
  • similar to nuclear receptor co-repressor 2 (NCOR2) antibody
  • nuclear receptor co-repressor 2 (ncor2) antibody
  • nuclear receptor corepressor 2 (ncor2) antibody
  • nuclear receptor co-repressor 2 (NCOR2) antibody
  • ctg26 antibody
  • gb:be017685 antibody
  • N-CoR antibody
  • N-CoR2 antibody
  • NCOR2 antibody
  • si:bz71m17.2 antibody
  • SMAP270 antibody
  • smrt antibody
  • smrte antibody
  • smrte-tau antibody
  • tnrc14 antibody
  • TRAC antibody
  • trac-1 antibody
  • trac1 antibody

Protein level used designations for NCOR2

CTG repeat protein 26 , T3 receptor-associating factor , silencing mediator for retinoid and thyroid hormone receptors , thyroid-, retinoic-acid-receptor-associated corepressor , nuclear receptor corepressor 2 , nuclear receptor co-repressor 2 , N-CoR2 , TRAC , silencing mediator of retinoic acid and thyroid hormone receptor , silencing mediator of retinoid acid and thyroid hormone receptor , silencing mediator , thyroid hormone receptor

GENE ID SPECIES
9612 Homo sapiens
360801 Rattus norvegicus
416815 Gallus gallus
486242 Canis lupus familiaris
20602 Mus musculus
467150 Pan troglodytes
561503 Danio rerio
706261 Macaca mulatta
733898 Xenopus (Silurana) tropicalis
100059253 Equus caballus
100337057 Bos taurus
100581656 Nomascus leucogenys
538549 Bos taurus
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