Browse our anti-Notch1 (NOTCH1) Antibodies

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anti-Notch 1 Antibodies (NOTCH1)
On www.antibodies-online.com are 389 Notch 1 (NOTCH1) Antibodies from 35 different suppliers available. Additionally we are shipping Notch1 Kits (22) and Notch1 Proteins (12) and many more products for this protein. A total of 436 Notch1 products are currently listed.
Synonyms:
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
list all antibodies Gene Name GeneID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
NOTCH1 25496  

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Top referenced anti-Notch1 Antibodies

  1. Human Monoclonal Notch1 Primary Antibody for FACS, IHC (fro) - ABIN181989 : Dass, Choong: Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 5 references for 181989

  2. Human Monoclonal Notch1 Primary Antibody for CyTOF, FACS - ABIN256488 : Ray, Yao, Nowotny, Mumm, Zhang, Wu, Kopan, Goate: Evidence for a physical interaction between presenilin and Notch. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 5 references for 256488

  3. Human Polyclonal Notch1 Primary Antibody for FACS, ICC - ABIN4899863 : Brosh, Hrynyk, Shen, Waghray, Zheng, Lemischka: A dual molecular analogue tuner for dissecting protein function in mammalian cells. in Nature communications 2016 (PubMed)

  4. Human Monoclonal Notch1 Primary Antibody for ELISA (Capture), FACS - ABIN4899411 : Le Friec, Sheppard, Whiteman, Karsten, Shamoun, Laing, Bugeon, Dallman, Melchionna, Chillakuri, Smith, Drouet, Couzi, Fremeaux-Bacchi, Köhl, Waddington, McDonnell, Baker, Handford, Lea, Kemper: The CD46-Jagged1 interaction is critical for human TH1 immunity. in Nature immunology 2012 (PubMed)

  5. Human Monoclonal Notch1 Primary Antibody for FACS - ABIN4896080 : Piggott, Deng, Warrington, Younge, Kubo, Desai, Goronzy, Weyand: Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. in Circulation 2011 (PubMed)

  6. Human Monoclonal Notch1 Primary Antibody for IF, RPPA - ABIN2452671 : Harada, Sato, Ikeda, Hsu, Igarashi, Nakanuma: Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours. in Journal of clinical pathology 2013 (PubMed)

  7. Cow (Bovine) Polyclonal Notch1 Primary Antibody for WB - ABIN2781033 : Sahlgren, Gustafsson, Jin, Poellinger, Lendahl: Notch signaling mediates hypoxia-induced tumor cell migration and invasion. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against Notch1 Interaction Partners

Human Notch 1 (NOTCH1) interaction partners

  1. In conclusion, Notch siganling appears to be an important mediator of the liver inflammation by modulating hepatic IL-22 (show IL22 Antibodies)-secreting NKp46 (show NCR1 Antibodies)(+) innate lymphoid cells.

  2. High Notch1 expression is associated with basal-like breast cancer.

  3. High NOTCH1 expression is associated with T-cell leukemia.

  4. this is the first report of a NOTCH1 mutation associated with familial cases of a single ventricle defect

  5. High NOTCH1 expression is associated with ovarian cancer.

  6. These data suggest that a key pathomechanism for this novel form of muscular dystrophy with POGLUT1 (show POGLUT1 Antibodies) mutation is Notch-dependent loss of satellite cells.

  7. Genes that were dysregulated due to NOTCH1 haploinsufficiency in mice with shortened telomeres were concordant with proosteoblast and proinflammatory gene network alterations

  8. The PROX1 (show PROX1 Antibodies)/KLF2 (show KLF2 Antibodies) complex upregulates the expression of DTX1 (show DTX1 Antibodies) and DTX3L (show DTX3L Antibodies). DTX1 (show DTX1 Antibodies) and DTX3L (show DTX3L Antibodies), functioning as a heterodimeric Notch E3 ligase, concertedly downregulate NOTCH1 activity and enhance lymphatic sprouting

  9. Taken together, our data demonstrate that JNK (show MAPK8 Antibodies) regulates triple-negative breast cancer (TNBC)tumorigenesis by promoting CSC phenotype through Notch1 signaling via activation of c-Jun (show JUN Antibodies) and indicate that JNK/c-Jun/Notch1 signaling is a potential therapeutic target for TNBC

  10. Studied the correlation between histone acetylation and Notch1 expression in lung carcinoma; results show a significant correlation between the level of acetylation of histone H3 (show HIST3H3 Antibodies) surrounding the promoter region of Notch1, and expression of Notch1 in human lung cancer cell lines.

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. Dll4 (show DLL4 Antibodies)-Notch1 signalling couples sprouting angiogenesis and artery formation.

  2. Genes that were dysregulated due to NOTCH1 haploinsufficiency in mice with shortened telomeres were concordant with proosteoblast and proinflammatory gene network alterations

  3. this study shows that Notch signaling regulates basophils biological function, at least partially via the modulation of MAPK (show MAPK1 Antibodies)

  4. The PROX1 (show C16orf35 Antibodies)/KLF2 (show KLF2 Antibodies) complex upregulates the expression of DTX1 (show DTX1 Antibodies) and DTX3L (show DTX3L Antibodies). DTX1 (show DTX1 Antibodies) and DTX3L (show DTX3L Antibodies), functioning as a heterodimeric Notch E3 ligase, concertedly downregulate NOTCH1 activity and enhance lymphatic sprouting

  5. Postnatal development analysis revealed that in cilia-deficient corneal epithelial cells downregulation of the Notch pathway precedes cell proliferation defects.

  6. a2V deficiency disrupts the endolysosomal route in Notch and TGF signaling, thereby impairing mammary gland development.

  7. ACTG2 (show ACTG2 Antibodies) boosts the metastatic potential of hepatocellular carcinoma in a Notch1-dependent manner.

  8. The results have unraveled a novel molecular pathway driven by interactions between prion protein (PrP (show PRNP Antibodies)) and Notch1 in the progression of pancreatic ductal adenocarcinoma (PDAC), supporting a critical tumor-promoting role of Notch1 in PrP-expressing PDAC tumors.

  9. these results show that ADAM10 (show ADAM10 Antibodies)-Notch signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  10. Notch1 and Notch2 (show NOTCH2 Antibodies) are the primary Notch receptors regulating epithelial cell homoeostasis in mouse and human stomach.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin (show CTNNB1 Antibodies) in a process that does not depend on its phosphorylation by GSK3 (show GSK3b Antibodies)

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (show SHH Antibodies) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (show MMP11 Antibodies) gene or the constitutively active form of Notch (IC).

  4. ZFP423 (show 104125 Antibodies) coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 Antibodies) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (show RBPJ Antibodies)) pathway has a significant role in the PGC (show PGC Antibodies) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (show BCL6 Antibodies) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (show MAML1 Antibodies)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin (show Actbeta Antibodies)-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (show SMAD2 Antibodies) nuclear localization and the competence of ectodermal cells for activin A (show INHBA Antibodies) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. the NOTCH1 polymorphism g.A48250G was significantly associated with body height, body weight, and height at hip cross, and that g.A49239C only showed significant associations with body height

  2. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (show NOTCH3 Antibodies), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  3. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1) antibody
  • notch 1 (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (NOTCH1) antibody
  • notch 1 (Notch1) antibody
  • 9930111A19Rik antibody
  • hN1 antibody
  • lin-12 antibody
  • Mis6 antibody
  • N1 antibody
  • NOTCH antibody
  • notch-1 antibody
  • NOTCH1 antibody
  • notch1-a antibody
  • Tan1 antibody
  • xnotch antibody
  • xnotch1 antibody
  • Xotch antibody

Protein level used designations for anti-Notch 1 (NOTCH1) Antibodies

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

GENE ID SPECIES
100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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