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Browse our anti-Notch1 (NOTCH1) Antibodies

Full name:
anti-Notch 1 Antibodies (NOTCH1)
On www.antibodies-online.com are 300 Notch 1 (NOTCH1) Antibodies from 32 different suppliers available. Additionally we are shipping Notch1 Kits (11) and Notch1 Proteins (11) and many more products for this protein. A total of 336 Notch1 products are currently listed.
Synonyms:
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
list all antibodies Gene Name GeneID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
NOTCH1 25496  

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Most Popular Reactivities for anti-Notch1 (NOTCH1) Antibodies

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anti-Human Notch1 Antibodies:

anti-Mouse (Murine) Notch1 Antibodies:

anti-Rat (Rattus) Notch1 Antibodies:

All available anti-Notch1 Antibodies

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Top referenced anti-Notch1 Antibodies

  1. Human Monoclonal Notch1 Primary Antibody for ICS, IHC - ABIN967360 : Anderson, Robey, Huang: Notch signaling in lymphocyte development. in Current opinion in genetics & development 2001 (PubMed)
    Show all 8 references for ABIN967360

  2. Human Monoclonal Notch1 Primary Antibody for ICC, IHC (fro) - ABIN807923 : Espinosa, Santos, Inglés-Esteve, Muñoz-Canoves, Bigas: p65-NFkappaB synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR. in Journal of cell science 2002 (PubMed)
    Show all 7 references for ABIN807923

  3. Human Monoclonal Notch1 Primary Antibody for ICC, IHC (fro) - ABIN807924 : Kefas, Comeau, Floyd, Seleverstov, Godlewski, Schmittgen, Jiang, diPierro, Li, Chiocca, Lee, Fine, Abounader, Lawler, Purow: The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 6 references for ABIN807924

  4. Human Monoclonal Notch1 Primary Antibody for FACS, IHC (fro) - ABIN181989 : Dass, Choong: Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 5 references for ABIN181989

  5. Human Polyclonal Notch1 Primary Antibody for ELISA, WB - ABIN104897 : Gupta, Li, Abedin, Wang, Schneider, Najafian, Rosenberg: Effect of Notch activation on the regenerative response to acute renal failure. in American journal of physiology. Renal physiology 2009 (PubMed)
    Show all 2 references for ABIN104897

  6. Human Polyclonal Notch1 Primary Antibody for EIA, WB - ABIN117996 : Bertrand, Eckfeldt, Lysholm, LeBien: Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells. in Leukemia 2001 (PubMed)
    Show all 2 references for ABIN117996

  7. Human Polyclonal Notch1 Primary Antibody for EIA, IHC (p) - ABIN117997 : Gridley: Notch signaling and inherited disease syndromes. in Human molecular genetics 2003 (PubMed)
    Show all 2 references for ABIN117997

  8. Chicken Polyclonal Notch1 Primary Antibody for WB - ABIN2781033 : Sahlgren, Gustafsson, Jin, Poellinger, Lendahl: Notch signaling mediates hypoxia-induced tumor cell migration and invasion. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  9. Human Monoclonal Notch1 Primary Antibody for IF, RPPA - ABIN2452671 : Harada, Sato, Ikeda, Hsu, Igarashi, Nakanuma: Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours. in Journal of clinical pathology 2013 (PubMed)

More Antibodies against Notch1 Interaction Partners

Pig (Porcine) Notch 1 (NOTCH1) interaction partners

  1. Notch1 regulates the proliferation of porcine satellite cells through the activation of Hes5 (show HES5 Antibodies).

Human Notch 1 (NOTCH1) interaction partners

  1. Inhibition of WNT (show WNT2 Antibodies) signaling by the PORCN (show PORCN Antibodies) inhibitor WNT974 reduced metastatic spread of UM-SCC (show CYP11A1 Antibodies) cells, especially in UM-SCCs with Notch1 deficiency.

  2. The role of CSL (show CSHL1 Antibodies)-dependent and independent Notch signaling pathways in cell apoptosis is described in normal tissue homeostasis and in tumorigenesis. (Review)

  3. Data suggest that FAM84B protein and the NOTCH pathway are involved in the progression of esophageal squamous cell carcinoma (ESCC) and may be potential diagnostic targets for ESCC susceptibility.

  4. High Notch1 expression is associated with colorectal cancer.

  5. High Notch1 expression is associated with Prostatic Intraepithelial Neoplasia.

  6. findings provide evidence for a novel cell-autonomous pro-inflammatory Jagged1 (show JAG1 Antibodies)-Notch1 pathway in endothelial cells

  7. Down-regulation of Notch1 by gamma-secretase inhibitors or siRNA combined with IL-24 (show IL24 Antibodies) can sensitize apoptosis and decrease the invasion and migration capabilities of HepG2 cells.

  8. Findings of frequent mutations in CDKN2A (show CDKN2A Antibodies), NOTCH1, PIK3CA (show PIK3CA Antibodies), and EGFR (show EGFR Antibodies) (all in excess (show RCC1 Antibodies) of 20%) point to potential therapeutic avenues. Trials of targeted therapies directed toward these mutations should be explored.

  9. Authors review how NOTCH1 and p16 (show CDKN2A Antibodies) contribute in head and neck cancer development and how microRNAs quantitatively control their expression. [Review]

  10. TF3 suppressed the cleavage of Notch-1, subsequently decreased the expression of c-Myc, HIF-1a and VEGF, and finally the impaired cancer cells induced angiogenesis

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. Data suggest that expression of Notch-1 receptor in endothelial progenitor cells (EPC (show TCF21 Antibodies)) in bone marrow is up-regulated in diabetic angiopathy (DA); signaling in EPC (show TCF21 Antibodies) via Notch-1 receptor and VEGFA (show VEGFA Antibodies)/VEGFR2 (show KDR Antibodies) appears to be altered in DA.

  2. Data indicate that Notch receptors Notch1 and Notch3 (show NOTCH3 Antibodies) deficiency compromises pericyte function and contributes to vascular pathologies.

  3. the cardioprotective effect of Notch1 against ischemic damage is mediated by AMPK (show PRKAA1 Antibodies) signaling via an interaction with upstream LKB1 (show STK11 Antibodies).

  4. Epidermal Notch1 recruits RORgamma(+) group 3 innate lymphoid cells to orchestrate normal skin repair.

  5. Jagged1 (show JAG1 Antibodies) intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart.

  6. Data show that the proliferation of sustained expression of Notch1-induced choroid plexus (CP) tumours relies on Sonic Hedgehog (Shh (show SHH Antibodies)) from the tumour microenvironment through their primary cilium.

  7. The physical interaction of NBEA (show NBEA Antibodies) with NOTCH1 is most relevant for autism spectrum disorders pathogenesis because NOTCH signaling is essential for neural development.

  8. LFNG (show LFNG Antibodies) protein may have context-dependent effects on Notch activity

  9. A transgenic mouse model in which the Notch1 intracellular domain (NIC (show NCSTN Antibodies)) is activated.

  10. Dll4 (show DLL4 Antibodies)/Notch signaling and HIF-1alpha (show HIF1A Antibodies) are closely related to lymphangiogenesis in dry eye-induced lacrimal glands.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin (show CTNNB1 Antibodies) in a process that does not depend on its phosphorylation by GSK3 (show GSK3b Antibodies)

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (show SHH Antibodies) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (show MMP11 Antibodies) gene or the constitutively active form of Notch (IC).

  4. ZFP423 (show 104125 Antibodies) coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 Antibodies) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (show RBPJ Antibodies)) pathway has a significant role in the PGC (show PGC Antibodies) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (show BCL6 Antibodies) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (show MAML1 Antibodies)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin (show Actbeta Antibodies)-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (show SMAD2 Antibodies) nuclear localization and the competence of ectodermal cells for activin A (show INHBA Antibodies) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (show NOTCH3 Antibodies), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  2. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1) antibody
  • notch 1 (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (NOTCH1) antibody
  • notch 1 (Notch1) antibody
  • 9930111A19Rik antibody
  • hN1 antibody
  • lin-12 antibody
  • Mis6 antibody
  • N1 antibody
  • NOTCH antibody
  • notch-1 antibody
  • NOTCH1 antibody
  • notch1-a antibody
  • Tan1 antibody
  • xnotch antibody
  • xnotch1 antibody
  • Xotch antibody

Protein level used designations for anti-Notch 1 (NOTCH1) Antibodies

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

GENE ID SPECIES
100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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