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Browse our anti-Notch1 (NOTCH1) Antibodies

Full name:
anti-Notch 1 Antibodies (NOTCH1)
On www.antibodies-online.com are 373 Notch 1 (NOTCH1) Antibodies from 34 different suppliers available. Additionally we are shipping Notch1 Kits (13) and Notch1 Proteins (11) and many more products for this protein. A total of 411 Notch1 products are currently listed.
Synonyms:
9930111A19Rik, hN1, lin-12, Mis6, N1, NOTCH, notch-1, NOTCH1, notch1-a, Tan1, xnotch, xnotch1, Xotch
list all antibodies Gene Name GeneID UniProt
NOTCH1 4851 P46531
NOTCH1 18128 Q01705
NOTCH1 25496  

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Most Popular Reactivities for anti-Notch1 (NOTCH1) Antibodies

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anti-Human Notch1 Antibodies:

anti-Mouse (Murine) Notch1 Antibodies:

anti-Rat (Rattus) Notch1 Antibodies:

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Top referenced anti-Notch1 Antibodies

  1. Human Monoclonal Notch1 Primary Antibody for FACS, IHC (fro) - ABIN181989 : Dass, Choong: Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. in Molecular cancer therapeutics 2007 (PubMed)
    Show all 5 references for ABIN181989

  2. Human Monoclonal Notch1 Primary Antibody for CyTOF, FACS - ABIN256488 : Ray, Yao, Nowotny, Mumm, Zhang, Wu, Kopan, Goate: Evidence for a physical interaction between presenilin and Notch. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 5 references for ABIN256488

  3. Human Monoclonal Notch1 Primary Antibody for ICC, IF - ABIN4340379 : Groeneweg, Hall, Zhang, Kim, Byron, Tambouret, Sathayanrayanan, Foster, Rueda, Growdon: Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model. in Gynecologic oncology 2014 (PubMed)
    Show all 3 references for ABIN4340379

  4. Human Polyclonal Notch1 Primary Antibody for EIA, IHC (p) - ABIN117997 : Bertrand, Eckfeldt, Lysholm, LeBien: Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells. in Leukemia 2001 (PubMed)
    Show all 2 references for ABIN117997

  5. Human Polyclonal Notch1 Primary Antibody for EIA, WB - ABIN117996 : Gridley: Notch signaling and inherited disease syndromes. in Human molecular genetics 2003 (PubMed)
    Show all 2 references for ABIN117996

  6. Human Monoclonal Notch1 Primary Antibody for ELISA (Capture), FACS - ABIN4899411 : Le Friec, Sheppard, Whiteman, Karsten, Shamoun, Laing, Bugeon, Dallman, Melchionna, Chillakuri, Smith, Drouet, Couzi, Fremeaux-Bacchi, Köhl, Waddington, McDonnell, Baker, Handford, Lea, Kemper: The CD46-Jagged1 interaction is critical for human TH1 immunity. in Nature immunology 2012 (PubMed)

  7. Human Monoclonal Notch1 Primary Antibody for IF, RPPA - ABIN2452671 : Harada, Sato, Ikeda, Hsu, Igarashi, Nakanuma: Notch1-Hes1 signalling axis in the tumourigenesis of biliary neuroendocrine tumours. in Journal of clinical pathology 2013 (PubMed)

  8. Human Monoclonal Notch1 Primary Antibody for FACS - ABIN4896081 : Piggott, Deng, Warrington, Younge, Kubo, Desai, Goronzy, Weyand: Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. in Circulation 2011 (PubMed)

  9. Chicken Polyclonal Notch1 Primary Antibody for WB - ABIN2781033 : Sahlgren, Gustafsson, Jin, Poellinger, Lendahl: Notch signaling mediates hypoxia-induced tumor cell migration and invasion. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against Notch1 Interaction Partners

Pig (Porcine) Notch 1 (NOTCH1) interaction partners

  1. Notch1 regulates the proliferation of porcine satellite cells through the activation of Hes5 (show HES5 Antibodies).

Human Notch 1 (NOTCH1) interaction partners

  1. our results show for the first time that miR (show MLXIP Antibodies)-101 acts as a tumor suppressor in T-cell acute lymphoblastic leukaemia and it could enhance chemotherapeutic sensitivity. Furthermore, Notch1 was identified to be a novel target of miR (show MLXIP Antibodies)-101. This study indicates that miR (show MLXIP Antibodies)-101 may represent a potential therapeutic target for T-cell acute lymphoblastic leukemia intervention.

  2. This study provides novel evidences of the mechanisms integrating Notch and TNF-alpha (show TNF Antibodies) signaling in the transcriptional induction of GATA3 (show GATA3 Antibodies) and HOXB4 (show HOXB4 Antibodies).

  3. Tbeta4 gene silencing in A549 and H1299 cells inhibited cell proliferation, migration, and invasion in vitro and decreased tumor growth in vivo. Mechanistic investigations revealed a significant decrease in Notch1 activation in Tbeta4 gene-silenced cells.

  4. Downregulation of microRNA-429 protects cardiomyocytes against hypoxia-induced apoptosis by increasing Notch1 expression.

  5. High expression of Notch1 is associated with radiation resistance in pancreatic cancer.

  6. Notch signaling and ASCL1 (show ASCL1 Antibodies) expression may determine the cell behaviors of SCLC partly through modifying EMT (show ITK Antibodies) phenotypes.

  7. insertion expansion mutations in the NOTCH1 juxtamembrane region may be generated by complex mechanisms including tandem duplications, de novo insertions and partial intronic retention events in combination with alternative splicing.

  8. Notch and TGFbeta (show TGFB1 Antibodies) form a reciprocal positive regulatory loop and cooperatively regulate Epithelial-mesenchymal transition and promote epithelial ovarian cancer cell motility and migration.

  9. TGFBR2 (show TGFBR2 Antibodies) signaling can affect Notch1 glycosylation via regulation of glycosyltransferase (show GTDC2 Antibodies) LFNG (show LFNG Antibodies) expression and provide a first mechanistic example for altered glycosylation in microsatellite instability colorectal tumor cells.

  10. High Notch1 expression is associated with hepatocellular carcinoma.

Mouse (Murine) Notch 1 (NOTCH1) interaction partners

  1. Data show that liver progenitors differentiate into hepatocytes and cholangiocytes via transforming growth factor beta (TGFbeta (show TGFB1 Antibodies)) treatment and Notch receptors.

  2. miR (show MLXIP Antibodies)-342-5p acts as a multifunctional angiogenic repressor mediating the effects and interaction among angiogenic Notch1/VEGF (show VEGFA Antibodies)/TGF-beta (show TGFB1 Antibodies) signaling pathways.

  3. This study showed the effects of VEGF on excitatory synaptic transmission but also defines a role for the Notch1 receptor in mediating the response of synaptic activity to VEGF.

  4. we identified Notch1 signaling as a key determinant of triacylglycerol metabolism in response to a high fat diet, and we further revealed novel biological actions of Notch1 signaling pathways on the regulation of lipid oxidation.

  5. Interactions among the TGF-beta (show TGFB1 Antibodies) signalling pathways, Jagged2 (show JAG2 Antibodies)/Notch1 signalling pathways and epigenetic modifications regulate the expansion of lingual epithelial stem cells.

  6. polarizing macrophages toward a pro-inflammatory profile further increased their angiotrophic stimulation of vessel sprouting, and this increase was dependent on macrophage Notch signaling.

  7. Notch1 inhibition by siRNA or DAPT reduces low shear stress-induced plaque formation

  8. The consequences of Notch1 gain-of-function signaling on female reproductive tract development in mice with conditionally activated Notch1 is reported; mutant females demonstrated inflamed uteri with increased vascularization and an influx of inflammatory cells and older females developed ovarian, oviductal, and uterine cysts.

  9. Data show that the phenotype of Notch activation in osteocytes was prevented in matrix protein 1 (Dmp1 (show DMP1 Antibodies))-Cre;Rosa(Notch) mice hemizygous for the Dmp1 (show DMP1 Antibodies)-sclerostin (SOST (show SOST Antibodies)) transgene.

  10. High Notch promoted stem-ness characteristics and metastasis potential in sphere-forming liver cancer stem cells.

Xenopus laevis Notch 1 (NOTCH1) interaction partners

  1. Notch initially destabilises beta-catenin (show CTNNB1 Antibodies) in a process that does not depend on its phosphorylation by GSK3 (show GSK3b Antibodies)

  2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh (show SHH Antibodies) expression in the midline.

  3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 (show MMP11 Antibodies) gene or the constitutively active form of Notch (IC).

  4. ZFP423 (show 104125 Antibodies) coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 (show HES5 Antibodies) gene expression.

  5. results suggest that a cell-to-cell interaction via the Notch/Su(H (show RBPJ Antibodies)) pathway has a significant role in the PGC (show PGC Antibodies) migration by regulating cell motility

  6. the process of delimiting the three germ layers requires Notch signaling.

  7. BCL6 (show BCL6 Antibodies) inhibits transcription by competing for the Notch1 intracellular domain, preventing the coactivator Mastermind-like1 (MAM1 (show MAML1 Antibodies)) from binding.

  8. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis

  9. Notch signaling is activated when activin (show Actbeta Antibodies)-like signaling induces various tissues from homogenous undifferentiated cells.

  10. Notch controls smad2 (show SMAD2 Antibodies) nuclear localization and the competence of ectodermal cells for activin A (show INHBA Antibodies) in Xenopus embryos

Cow (Bovine) Notch 1 (NOTCH1) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 and Notch3 (show NOTCH3 Antibodies), suggesting that ORF2 interfered with the trans-activation potential of Notch.

  2. Cellular size or Notch1 expression is not per se a specific marker for mesenchymal progenitor cells in adult articular cartilage.

Notch1 (NOTCH1) Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Alternative names and synonyms associated with Notch1 (NOTCH1)

  • notch 1 (notch1) antibody
  • notch 1 (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (Drosophila) (NOTCH1) antibody
  • Notch homolog 1, translocation-associated (NOTCH1) antibody
  • notch 1 (Notch1) antibody
  • 9930111A19Rik antibody
  • hN1 antibody
  • lin-12 antibody
  • Mis6 antibody
  • N1 antibody
  • NOTCH antibody
  • notch-1 antibody
  • NOTCH1 antibody
  • notch1-a antibody
  • Tan1 antibody
  • xnotch antibody
  • xnotch1 antibody
  • Xotch antibody

Protein level used designations for anti-Notch 1 (NOTCH1) Antibodies

notch 1 , Notch homolog 1, translocation-associated (Drosophila) , Notch homolog 1, translocation-associated , neurogenic locus notch homolog protein 1 , translocation-associated notch protein TAN-1 , Motch A , Notch gene homolog 1 , mT14 , major type A protein , p300 , transmembrane receptor Notch1 , Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila) , neurogenic locus notch protein homolog , NOTCH-1

GENE ID SPECIES
100190917 Oncorhynchus mykiss
100631526 Amphimedon queenslandica
720888 Macaca mulatta
100037842 Xenopus (Silurana) tropicalis
100068764 Equus caballus
100144593 Sus scrofa
100224074 Taeniopygia guttata
4851 Homo sapiens
18128 Mus musculus
25496 Rattus norvegicus
394367 Xenopus laevis
395655 Gallus gallus
464865 Pan troglodytes
480676 Canis lupus familiaris
767866 Bos taurus
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