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Browse our NOTCH2 (NOTCH2) ELISA Kits

Full name:
Notch 2 ELISA Kits (NOTCH2)
On www.antibodies-online.com are 15 Notch 2 (NOTCH2) ELISA Kits from 7 different suppliers available. Additionally we are shipping NOTCH2 Antibodies (198) and NOTCH2 Proteins (12) and many more products for this protein. A total of 234 NOTCH2 products are currently listed.
Synonyms:
AGS2, AI853703, HJCYS, hN2, N2, notch6, sb:cb884
list all ELISA KIts Gene Name GeneID UniProt
NOTCH2 4853 Q04721
NOTCH2 18129 O35516
NOTCH2 29492 Q9QW30

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NOTCH2 (NOTCH2) ELISA Kits by Reactivity

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Human Notch 2 (NOTCH2) interaction partners

  1. Low levels of Notch pathway genes Notch1, Notch2, Notch4 and Jagged1 correlated with poor prognostic factors such as larger tumor size, positive lymph-node status, tumor phenotype and infiltrating tumor Treg cells.

  2. Together, these data show that miR (show MLXIP ELISA Kits)-181a may play an essential role in GSC (show GSC ELISA Kits) formation and GBM progression by targeting Notch2, suggesting that Notch2 and miR (show MLXIP ELISA Kits)-181a have potential prognostic value as tumor biomarkers in GBM patients.

  3. MicroRNA-146a may increase the IL-6 (show IL6 ELISA Kits) levels and exacerbate Graves Ophthalmopathy by directly targeting Notch2.

  4. High NOTCH2 expression is associated with metastasis in colorectal cancer.

  5. this study shows that Treg cells infiltrating uveitic eyes display elevated Notch2 expression

  6. miR (show MLXIP ELISA Kits)-146a-5p functions as a tumour-suppressive miRNA targeting Notch2 and inhibits the EMT (show ITK ELISA Kits) progression of ESCC

  7. Findings indicate that niclosamide inhibits the progression of colon cancer by downregulating Notch1 (show NOTCH1 ELISA Kits), Notch2 and Notch3 (show NOTCH3 ELISA Kits) signaling and by upregulating the microRNA miR (show MLXIP ELISA Kits)-200 family members (miR200a, miR (show MLXIP ELISA Kits)-200b, miR (show MLXIP ELISA Kits)-200c).

  8. Notch2 may confer stemness properties in HCC (show FAM126A ELISA Kits).

  9. Macrophage notch1 (show NOTCH1 ELISA Kits) may play a more important role than notch2 and notch 3 (show NOTCH3 ELISA Kits) in the regulation of NF-kappaB (show NFKB1 ELISA Kits) signaling pathway in atherosclerosis.

  10. AGS (show JAG1 ELISA Kits) is caused by mutations in one of two genes, namely, JAG1 (show JAG1 ELISA Kits) or NOTCH2. These genes are part of the Notch (show NOTCH1 ELISA Kits) signaling pathway, which is involved in cell fate determination. JAG1 (show JAG1 ELISA Kits) mutations have been identified in 70-94% of individuals with clinically diagnosed AGS (show JAG1 ELISA Kits)

Mouse (Murine) Notch 2 (NOTCH2) interaction partners

  1. These results suggested that Notch2 signaling is linked to c-Myc (show MYC ELISA Kits) expression and plays a key role in the regulation of MSC (show MSC ELISA Kits) proliferation.

  2. this study shows that Notch2 activity is required for the maintenance of lung tissue-resident memory CD103 (show ITGAE ELISA Kits)+ T cells

  3. In this study, authors use a smooth muscle-specific (show EIF3K ELISA Kits) deletion of Notch2 together with a global Notch3 (show NOTCH3 ELISA Kits) deletion to produce mice with combinations of mutant and wild-type Notch2/3 alleles in vascular smooth muscle cells

  4. 6955C-->T mutation in the Notch2 locus leading to cancellous and cortical bone osteopenia.

  5. Data (including data from studies in transgenic/knockout mice) suggest deletion of Notch1 (show NOTCH1 ELISA Kits) in podocytes prevents diabetic nephropathy development and up-regulates Notch2 expression; overexpression of Notch2 does not promote diabetic nephropathy.

  6. Expression of Notch1 and Notch2 was decreased in regenerated epidermis of wounds, where features of keratinocytes were altered. Notch1 and Notch2 down-regulation contributed to the induction of interleukin-36alpha expression.

  7. data indicate distinct effects of Notch (show NOTCH1 ELISA Kits) signaling on invariant natural killer T cells in the thymus and liver, which are at least partly independent of RBP-j (show RBPJ ELISA Kits) in the thymus.

  8. Notch1 (show NOTCH1 ELISA Kits) and Notch2 intracellular domains are functionally equivalent during development and carcinogenesis

  9. NOTCH2 inhibits PDGF-B (show PDGFB ELISA Kits)-dependent proliferation and its expression is decreased by PDGF-B (show PDGFB ELISA Kits).

  10. BTK (show BTK ELISA Kits) synergizes with Notch2 to govern marginal zone B cells in non-obese diabetic mice.

Cow (Bovine) Notch 2 (NOTCH2) interaction partners

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 (show NOTCH1 ELISA Kits) and Notch3 (show NOTCH3 ELISA Kits), suggesting that ORF2 interfered with the trans-activation potential of Notch (show NOTCH1 ELISA Kits).

Zebrafish Notch 2 (NOTCH2) interaction partners

  1. DeltaC/Notch1a and Notch2 signaling is responsible for a survival signal provided by xanthophores to melanophores.

NOTCH2 Antigen Profile

Antigen Summary

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NOTCH2

  • notch 2 (NOTCH2) Elisa Kit
  • notch 2 (notch2) Elisa Kit
  • notch 2 (Notch2) Elisa Kit
  • notch homolog 2 (notch2) Elisa Kit
  • AGS2 Elisa Kit
  • AI853703 Elisa Kit
  • HJCYS Elisa Kit
  • hN2 Elisa Kit
  • N2 Elisa Kit
  • notch6 Elisa Kit
  • sb:cb884 Elisa Kit

Protein level used designations for Notch 2 (NOTCH2) ELISA Kits

notch 2 , neurogenic locus notch homolog protein 2-like , Notch homolog 2 , neurogenic locus notch homolog protein 2 , Motch B , Notch gene homolog 2 , notch gene homolog 2 , notch receptor protein 6

GENE ID SPECIES
581186 Strongylocentrotus purpuratus
100081510 Ornithorhynchus anatinus
100464781 Ailuropoda melanoleuca
100567900 Anolis carolinensis
100584613 Nomascus leucogenys
100224680 Taeniopygia guttata
4853 Homo sapiens
457173 Pan troglodytes
483148 Canis lupus familiaris
18129 Mus musculus
29492 Rattus norvegicus
100153369 Sus scrofa
513730 Bos taurus
58065 Danio rerio
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