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Browse our Estrogen Receptor 2 (ER Beta) Proteins (ESR2)

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Estrogen Receptor 2 (ER Beta) Proteins (ESR2)
On are 17 Estrogen Receptor 2 (ER Beta) (ESR2) Proteins from 9 different suppliers available. Additionally we are shipping Estrogen Receptor 2 (ER Beta) Antibodies (417) and Estrogen Receptor 2 (ER Beta) Kits (46) and many more products for this protein. A total of 497 Estrogen Receptor 2 (ER Beta) products are currently listed.
CERB, er, ER-BETA, ERB, erb1, Erb2, erbeta, ERBeta2, ER[b], ER[b]1, ESR-BETA, Esr2, ESRB, ESTRB, NR3A2, zfER-beta1, zfER[b]1
list all proteins Gene Name GeneID UniProt
ESR2 13983 O08537
ESR2 2100 Q92731
ESR2 25149 Q62986

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Estrogen Receptor 2 (ER Beta) Proteins (ESR2) by Origin

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Zebrafish Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. although esr2b mutant fish showed unaltered antibacterial responses, they were unable to mount an effective antiviral response upon viral challenge.

  2. This study revealed similar patterns of transcript abundance across reproductive morphs for ERbeta1, ERbeta2, ERalpha (show ESR1 Proteins), and aromatase in the forebrain and saccule.

  3. It was concluded that morpholino (MO) oligonucleotid technology in zebrafish embryos is an good approach for investigating the interplay of estrogen receptor (show ESR1 Proteins) subtypes in a true physiological context.

  4. during embryogenesis two of the three 17beta-estradiol receptor genes, esr1 and esr2b are expressed, and in presence of ligand the mRNA levels of these two genes increase

  5. Data show that temperature and photoperiod significantly influence the transcription of the estrogen-responsive genes, Vtg1, Vtg2, ER alpha (show ESR1 Proteins) and ER beta after a 21-day exposure to endocrine-disrupting chemicals.

  6. Cloning of the cDNAs corresponding to three oestrogen receptors (esr1 (show ESR1 Proteins), ERalpha (show ESR1 Proteins); esr2b, ERbeta1; and esr2a (show ESR1 Proteins), ERbeta2 ).

  7. Data show that the hepatic expression of estrogen receptor alpha (show ESR1 Proteins), beta1 and beta2 genes responds differently to estradiol.

  8. genistein binds and activates the three zebrafish estrogen receptors ERalpha (show ESR1 Proteins), ERbeta-A and ERbeta-B (show ESR1 Proteins) and induces apoptosis in an ER-independent manner

Horse (Equine) Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. The presence of a single isoform of ESR1 (66kDa) and ESR2 (61kDa) was found by Western-blot analysis in samples from seven stallions and the expression of the seven transmembrane estradiol binding receptor GPER in colt testis.

  2. expression of estrogen receptor alpha (show ESR1 Proteins) and beta and progesterone receptor (show PGR Proteins) in equine microplacentomes gives evidence for a role of placental steroids as regulators of placental function

Medaka Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. cloned three ER subtypes (ERalpha (show ESR1 Proteins), ERbeta1, and ERbeta2), and examined their developmental expression in the gonads of females and males during embryonic and larval development

  2. The expression of androgen receptors, estrogen receptor beta, and bone morphogenetic protein 2b (show BMP4 Proteins) in male and female Japanese and Thai medaka are reported.

Mouse (Murine) Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. Results demonstrate that ERalpha (show ESR1 Proteins), ERbeta, and GPER1 all participate in the rapid effects of 17beta-estradiol-3-benzoate on hippocampal synaptic function

  2. ERalpha (show ESR1 Proteins) responses E2-induced ERRalpha (show ESRRA Proteins) activation, while ERbeta responses the basal expression

  3. Study demonstrates different roles of estrogen receptor alpha (show ESR1 Proteins) and estrogen receptor beta in rapid modulation of spinogenesis and LTD by estradiol.

  4. that estrogen biphasically modulates prostate tumor formation by regulating Kruppel-like zinc finger transcription factor (show OSR1 Proteins) 5 (show CEBPB Proteins)-dependent transcription through estrogen receptor beta

  5. Buk music reduced levels of tumor necrosis factor-alpha (show TNF Proteins), and significantly increased estrogen receptor-beta mRNA levels in brain using Buk music as a means of treating anaphylaxis.

  6. ERbeta-exerted regulation of PPARgamma (show PPARG Proteins) expression and activity is critical for diosgenin-inhibited adipocyte differentiation.

  7. Study reveals how endometrial tissue generated by retrograde menstruation can escape immune surveillance and develop into sustained ectopic lesions via gain of ERbeta function.

  8. found that ERbeta is targeted for repression in prostate cancer caused by PTEN deletion and that loss of ERbeta is important for tumor formation

  9. In model of chronic unpredictable mild stress significant (P<0.05) increase in ERbeta mRNA and protein expression levels in hippocampus and cortex in mice.

  10. ESR2 may be downstream of the ERK1/2 pathway in mediating the effect of CDKN1A (show CDKN1A Proteins) on nerve growrh factor-induced granulosa cell proliferation.

Human Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. Knockdown of METTL17 (show METTL17 Proteins) reduces transcriptional activities of ESR1 (show ESR1 Proteins) and ESR2 in breast cancer cells.

  2. Reduction of estrogen receptor beta expression is associated with inflammatory bowel disease.

  3. Results of the meta-analysis revealed a potential benefit of positive ESR1 (show ESR1 Proteins) mRNA expression in survival in patients with NSCLC, especially in those of advanced stage. No statistically significant association was found between ESR2 mRNA expression and NSCLC patients' prognosis.

  4. Data shows that ESR2 is expressed in more that 50% of normal mammary epithelial cells, in 10% in invasive ductal carcinoma, and 61% of tumor infiltrating leucocytes. Lobular breast neoplasm expresses high levels of both ESR1 (show ESR1 Proteins) and ESR2. [review]

  5. Data show that estrogen receptor beta (ERbeta) functions as a repressor of hypoxia-inducible factor 1 (show HIF1A Proteins), alpha subunit (show POLG Proteins) (HIF-1alpha (show HIF1A Proteins))-mediated NF-kappa B (show NFKB1 Proteins) (NF-kB) activation.

  6. ERbeta may be a useful biomarker for risk stratification and a novel therapeutic target for breast cancer risk reduction

  7. Estrogen receptor Beta-positive cases of squamous cell lung carcinoma were at risk for poor outcome.

  8. Findings of the current study suggest that the ER-beta gene polymorphisms are not major determinants of the development of recurrent pregnancy loss in Korean women.

  9. The greater the levels of ER-beta expression, tissue inflammation, and angiogenesis are, the more severe de Quervain's disease is. ER-beta might be a useful target for novel de Quervain's disease therapy.

  10. autocrine IFN-g (show IFNG Proteins) in MCF-7 increases mRNA expression of ERb resulting in enhanced sensitivity to tamoxifen (TAM (show CCNA1 Proteins)). These results indicate that ERbetaand autocrine IFN-g (show IFNG Proteins) represent two putative targets for breast cancer therapy.

Pig (Porcine) Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 (show F2R Proteins) and PAR-2 (show F2RL1 Proteins)) associate with breast cancer outcome in an estrogen receptor (ER (show ESR1 Proteins))-dependent manner.

  2. results might shed new light on the roles of estrogen receptor (show ESR1 Proteins) 2(ESR2) in spermatogenesis as candidate for boar fertility

  3. Downregulation of the ERs, particularly ERalpha (show ESR1 Proteins) in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus.

  4. the results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function

  5. ERbeta mRNA was found only in Sertoli cells in the testis.

  6. positive staining for ERalpha (show ESR1 Proteins) in the nuclei of skeletal muscle cells, while the ERbeta stain showed positive signals in nuclei and cytoplasm of skeletal myofibers and myoblasts derived from satellite cells

  7. ESR2 gene polymorphisms are associated with litter size.

  8. The objective of this study was to search for polymorphisms in the coding region of the estrogen receptors 1 and 2 (ESR1 (show ESR1 Proteins) and ESR2) and to analyze the effects of these variants and the well known intronic ESR1 (show ESR1 Proteins) PvuII polymorphism on litter size.

  9. These data demonstrate novel and differential mechanisms by which ERalpha (show ESR1 Proteins) and ERbeta activation control coronary artery vasoreactivity in males and females and regulate vascular NO and O(2)(-) formation.

  10. Pig ejaculated spermatozoa express estrogen receptor (show ESR1 Proteins).

Cow (Bovine) Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. The mRNA expression of ER-alpha (show ESR1 Proteins) and ER-beta in the hypothalamus of developing male and female bovines, is reported.

  2. ER-alpha (show ESR1 Proteins) is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex.

  3. fetal ovary of cattle has the steroidogenic enzyme aromatase (show CYP19A1 Proteins) to convert androgens to estradiol-17beta, and estrogen receptors alpha and beta to facilitate an estrogen response within the fetal ovary

  4. there are different levels of ERalpha (show ESR1 Proteins), ERbeta and PR in bovine oviducts at different cycle stages in vivo

  5. The expression of estrogen and progesterone receptors in ovarian follicular structures from cows with cystic ovarian disease (COD (show SNRPB Proteins)) and a comparison of these with normal ovarian structures are reported.

  6. These data indicate that PGF2alpha, TNFalpha (show TNF Proteins) and IFNgamma regulate ERalpha (show ESR1 Proteins) and ERbeta mRNA expressions in bovine luteal cells.

  7. Roles of IGF-I (show IGF1 Proteins) and the estrogen, androgen and IGF-I (show IGF1 Proteins) receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.

Goat Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. The main functional structure domains of the ESR2 in a Jining Gray female goat have been described.

Rhesus Monkey Estrogen Receptor 2 (ER Beta) (ESR2) interaction partners

  1. an 17b-estradiol-induced increase in the proliferation of rhesus retinal capillary endothelial cells may be mediated by the action of ERb.

Estrogen Receptor 2 (ER Beta) (ESR2) Protein Profile

Protein Summary

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.

Alternative names and synonyms associated with Estrogen Receptor 2 (ER Beta) (ESR2)

  • estrogen receptor 2b (esr2b)
  • estrogen receptor 2 (ER beta) (esr2)
  • estrogen receptor 2 (ER beta) (ESR2)
  • estrogen receptor beta (esr2)
  • estrogen receptor beta 2 (erb2)
  • estrogen receptor beta (LOC100136443)
  • estrogen receptor beta 1 (erb1)
  • estrogen receptor type beta (LOC100304489)
  • estrogen receptor 2 (beta) (Esr2)
  • estrogen receptor 2 (ER beta) (Esr2)
  • estrogen receptor beta (erbeta)
  • CERB protein
  • er protein
  • ER-BETA protein
  • ERB protein
  • erb1 protein
  • Erb2 protein
  • erbeta protein
  • ERBeta2 protein
  • ER[b] protein
  • ER[b]1 protein
  • ESR-BETA protein
  • Esr2 protein
  • ESRB protein
  • ESTRB protein
  • NR3A2 protein
  • zfER-beta1 protein
  • zfER[b]1 protein

Protein level used designations for ESR2

ERbeta-A , NR3A2-A , estrogen receptor beta1 , estrogen receptor beta , estrogen receptor 2 (ER beta) , estradiol receptor beta , estrogen receptor beta 2 , estrogen receptor beta 1 , Nuclear receptor subfamily 3 group A member 2 , estrogen receptor beta-like , ER beta , ER-beta , nuclear receptor subfamily 3 group A member 2 , oestrogen receptor beta , estrogen nuclear receptor beta variant a , estrogen nuclear receptor beta variant b , estrogen receptor beta 4 , estrogen receptor 2 beta , steroid receptor , estrogen receptor 2 (beta)

317733 Danio rerio
394460 Xenopus (Silurana) tropicalis
452964 Pan troglodytes
100033964 Equus caballus
100049269 Oryzias latipes
100136323 Oncorhynchus mykiss
100136443 Salmo salar
100137064 Oncorhynchus mykiss
100303418 Papio anubis
100304489 Ictalurus punctatus
100459579 Pongo abelii
100471498 Ailuropoda melanoleuca
100595169 Nomascus leucogenys
13983 Mus musculus
2100 Homo sapiens
25149 Rattus norvegicus
443066 Ovis aries
403639 Canis lupus familiaris
396697 Sus scrofa
281146 Bos taurus
395575 Gallus gallus
100346748 Oryctolagus cuniculus
100731304 Cavia porcellus
100860823 Capra hircus
100415266 Callithrix jacchus
574110 Macaca mulatta
100170205 Oncorhynchus mykiss
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