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Browse our Estrogen-Related Receptor gamma Proteins (ESRRG)

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Estrogen-Related Receptor gamma Proteins (ESRRG)
On are 10 Estrogen-Related Receptor gamma (ESRRG) Proteins from 4 different suppliers available. Additionally we are shipping Estrogen-Related Receptor gamma Antibodies (105) and Estrogen-Related Receptor gamma Kits (7) and many more products for this protein. A total of 133 Estrogen-Related Receptor gamma products are currently listed.
DKFZp459J0417, ERR3, errb/g, errbeta/gamma, errg, errg2, errgamma, esrrg, esrrgl, LOC100125509, LOC100219115, LOC100230542, mKIAA0832, NR3B3, USH2A
list all proteins Gene Name GeneID UniProt
ESRRG 2104 P62508
ESRRG 26381 P62509
ESRRG 360896 P62510

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Estrogen-Related Receptor gamma Proteins (ESRRG) by Origin

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More Proteins for Estrogen-Related Receptor gamma Interaction Partners

Human Estrogen-Related Receptor gamma (ESRRG) interaction partners

  1. Data show that micrRNA miR-320a directly targets cAMP-regulated phosphoprotein 19 (ARPP-19) and estrogen-related receptor gamma protein (ERRgamma) in breast cancer cell lines.

  2. ERRgamma signaling is associated with poor DMFS in ER+, TAM (show CCNA1 Proteins)-treated breast cancer

  3. ESRRG is down-regulated in placenta from intrauterine growth restriction tissue.

  4. Results suggest that hypoxia-inducible factor-1alpha can positively regulate the dopaminergic phenotype through estrogen-related receptor gamma .

  5. The results reveal that the double-layer binding sites, namely, the ordinary ligand binding sites and their back support residues, substantiate the strong binding of BPA (show DST Proteins) to ERRgamma.

  6. A role for ESRRG in maternal blood pressure homeostasis during pregnancy.

  7. ERRgamma protein levels are affected by the activation state of ERK (show EPHB2 Proteins)/mitogen-activated protein kinase (show MAPK1 Proteins), and mutation of consensus ERK (show EPHB2 Proteins) target sites impairs ERRgamma-driven transcriptional activity and tamoxifen resistance.

  8. These findings demonstrate a novel ERRgamma/GATA4 (show GATA4 Proteins) signal cascade in the development of cardiac hypertrophy.

  9. Nuclear ANG (show ANG Proteins) directly binds to the ANG (show ANG Proteins)-Binding Sequence within ERRgamma of ERRgamma gene and inhibits ERRgamma transcription to promote breast cancer cell proliferation.

  10. ERRGamma mediates oxygen-dependent expression of genes involved in human trophoblast differentiation, function, and vascular homeostasis.

Mouse (Murine) Estrogen-Related Receptor gamma (ESRRG) interaction partners

  1. ERRgamma plays a key role in vascular calcification by upregulating the BMP2 (show BMP2 Proteins) signaling pathway.

  2. Mice lacking neuronal ERRgamma in cerebral cortex and hippocampus exhibit defects in spatial learning and memory.

  3. GSK5182 suppresses hypoxia-induced VEGF (show VEGFA Proteins) expression via ERRgamma; therefore, ERRgamma could be a treatment target for ischemic retinopathies

  4. These results suggest that ERRgamma is a major contributor to insulin (show INS Proteins) action in maintaining hepatic glucose homeostasis.

  5. ERRgamma is a sexdependent and RUNX2 (show RUNX2 Proteins)-dependent negative regulator of osteoblast differentiation, and that its regulatory activity may also be differentiation stage-dependent.

  6. Mice lacking both ERRalpha (show ESRRA Proteins) and cardiac Errg develop severe bradycardia, lethal cardiomyopathy, and heart failure featuring metabolic, contractile, and conduction dysfunctions.

  7. Orphan nuclear receptor (show NR1D1 Proteins) Errgamma induces C-reactive protein (show CRP Proteins) gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH (show CREB3L3 Proteins).

  8. Cartilage-specific overexpression of ERRgamma results in chondrodysplasia and reduced chondrocyte proliferation.

  9. These findings demonstrate a novel ERRgamma/GATA4 (show GATA4 Proteins) signal cascade in the development of cardiac hypertrophy.

  10. Esrrg modulates the intramacrophage proliferation of S. typhimurium by altering host iron homeostasis.

Estrogen-Related Receptor gamma (ESRRG) Protein Profile

Protein Summary

This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors\; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region.

Alternative names and synonyms associated with Estrogen-Related Receptor gamma (ESRRG)

  • estrogen-related receptor gamma b (esrrgb)
  • estrogen-related receptor gamma (ESRRG)
  • estrogen-related receptor gamma (esrrg)
  • estrogen-related receptor gamma type 1 (LOC100125509)
  • estrogen-related receptor gamma (LOC100219115)
  • estrogen-related receptor gamma (LOC100230542)
  • estrogen-related receptor gamma type 2 (errg2)
  • estrogen-related receptor gamma (Esrrg)
  • estrogen-related receptor gamma a (esrrga)
  • estrogen-related receptor gamma-like (LOC100622056)
  • DKFZp459J0417 protein
  • ERR3 protein
  • errb/g protein
  • errbeta/gamma protein
  • errg protein
  • errg2 protein
  • errgamma protein
  • esrrg protein
  • esrrgl protein
  • LOC100125509 protein
  • LOC100219115 protein
  • LOC100230542 protein
  • mKIAA0832 protein
  • NR3B3 protein
  • USH2A protein

Protein level used designations for ESRRG

NR3B2/3 , estrogen-related receptor beta/gamma , estrogen-related receptor gamma , Usher syndrome 2A (autosomal recessive, mild) , estrogen-related receptor gamma type 1 , estrogen-related receptor gamma type 2 , estrogen-related receptor gamma-like , ERR gamma-2 , estrogen receptor-related protein 3 , nuclear receptor subfamily 3 group B member 3 , estrogen-related receptor 3 , NR3B3

407691 Danio rerio
457738 Pan troglodytes
100050530 Equus caballus
100101684 Xenopus (Silurana) tropicalis
100125509 Oryzias latipes
100219115 Taeniopygia guttata
100230542 Taeniopygia guttata
100302427 Oryzias latipes
100397359 Callithrix jacchus
100598116 Nomascus leucogenys
2104 Homo sapiens
26381 Mus musculus
360896 Rattus norvegicus
421357 Gallus gallus
478961 Canis lupus familiaris
536732 Bos taurus
100172620 Pongo abelii
405890 Danio rerio
100622056 Sus scrofa
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