Browse our Peroxisome Proliferator-Activated Receptor alpha Proteins (PPARA)

On www.antibodies-online.com are 13 Peroxisome Proliferator-Activated Receptor alpha (PPARA) Proteins from 7 different suppliers available. Additionally we are shipping Peroxisome Proliferator-Activated Receptor alpha Antibodies (257) and Peroxisome Proliferator-Activated Receptor alpha Kits (53) and many more products for this protein. A total of 334 Peroxisome Proliferator-Activated Receptor alpha products are currently listed.
Synonyms:
4933429D07Rik, AW742785, hPPAR, LOC100136415, nr1c1, PPAR, PPAR-alpha, PPARALPHA, xppara, xPPARalpha
list all proteins Gene Name GeneID UniProt
PPARA 19013 P23204
PPARA 25747 P37230
PPARA 5465 Q07869

Peroxisome Proliferator-Activated Receptor alpha Proteins (PPARA) by Origin

More Proteins for Peroxisome Proliferator-Activated Receptor alpha Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. findings identify a new important innate immune function for the PPARalpha signaling pathway in regulating intestinal inflammation, mucosal immunity, and commensal homeostasis

  2. our data indicate that PPAR-alpha mediates antimicrobial responses to mycobacterial infection by inducing TFEB (show TFEB Proteins) and lipid catabolism.

  3. adiponectin (show ADIPOQ Proteins) inhibited endoplasmic reticulum stress and apoptosis of adipocyte in vivo and in vitro by activating the AMPK (show PRKAA1 Proteins)/PPARalpha/ATF2 (show ATF2 Proteins) pathway.

  4. It was concluded that decreased cardiac PPARalpha expression is essential for adaptive metabolic remodeling in hypoxia, but is prevented by dietary fat.

  5. these results indicate that PPAR-a accelerates important pathways for the clearance of a-ClFA, and a-ClFA may, in part, accelerate its catabolism by serving as a ligand for PPAR-a

  6. PPARgamma (show PPARG Proteins) controls the cancer stem cell niche

  7. In mice fed with a high-fat diet, palmitoleic acid supplementation stimulated the uptake of glucose in liver through activation of AMPK (show PRKAA1 Proteins) and FGF-21 (show FGF21 Proteins), and was dependent on PPARalpha.

  8. Myocardial PPARalpha is down-regulated in animals fed a high-fat diet.

  9. FGF21 (show FGF21 Proteins) is not critical for bone homeostasis or actions of PPARalpha and PPARgamma (show PPARG Proteins).

  10. Perfluoroalkyl acids addition to activating PPARalpha as a primary target, also have the potential to activate CAR, PPARgamma (show PPARG Proteins), and ERalpha (show ESR1 Proteins) as well as suppress STAT5B (show STAT5B Proteins).

Xenopus laevis Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

Human Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. Interference with PLIN2 (show PLIN2 Proteins) and PPARalpha resulted in major alterations in gene expression, especially affecting lipid, glucose, and purine metabolism.

  2. PPARalpha and FXR (show NR1H4 Proteins) function coordinately to integrate liver energy balance.

  3. An association was found with PPARalpha polymorphism and patients with nicotine dependency and schizophrenia.

  4. PPAR agonists have shown to have anti proliferative effect in squamous cell carcinoma of the head and neck.

  5. Results show that PPARalpha is downregulated and SREBP-1c (show SREBF1 Proteins) is upregulated in steatosis L-02 cells. These changes increase lipid synthesis and reduce lipid disposal, which ultimately lead to hepatic steatosis.

  6. Perfluoroalkyl acids addition to activating PPARalpha as a primary target, also have the potential to activate CAR, PPARgamma (show PPARG Proteins), and ERalpha (show ESR1 Proteins) as well as suppress STAT5B (show STAT5B Proteins).

  7. The CYP2E1 (show CYP2E1 Proteins)-PPARalpha axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  8. Studies indicate that natural dietary compounds, including nutrients and phytochemicals, are Peroxisome proliferator-activated receptor alpha (PPARalpha) ligands or modulators.

  9. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (show NR1I2 Proteins) and PPARalpha in primary human hepatocytes has been presented.

  10. Hepatitis B virus increases the expression of alpha-mannosidases both in vitro and in vivo via activation of the PPARalpha pathway by its envelope protein.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. The c.*636A>G SNP in the PPARA gene can be considered in Polish Landrace breed as a useful genetic marker for adipose tissue accumulation.

  2. The results indicate that the endometrial expression of PPARalpha genes fluctuates during the estrous cycle and pregnancy.

  3. PPARalpha is likely to play a central role in adaptation to fasting in pig liver

  4. Despite expression of PPAR-alpha in porcine myocardium and effects of fenofibrate on systemic metabolism, treatment with this PPAR-alpha activator does not alter myocardial metabolic or contractile responses to I/R in pigs.

  5. FISH localization of 4 BAC clones harbouring potential candidate genes for fatness traits: DGAT1 (show DGAT1 Proteins) (SSC4p15), PPARA (SSC5p15), ADIPOR1 (show ADIPOR1 Proteins) (SSC10p13) and CREB (show CREB1 Proteins) (SSC15q24)

  6. PPAR profiles in bladder smooth muscle (BSM) may contribute to the susceptibility of BSM to lipotoxicity in the metabolic syndrome.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor alpha (PPARA) interaction partners

  1. This study investigated FA composition in yaks and cattle, in order to ascertain whether a correlation between PPARalpha signal pathway genes as candidate genes and meat FA composition in yaks and cattle exists.

  2. OCTN2 (show SLC22A5 Proteins) expression and carnitine transport in cattle, as in rodents, are regulated by PPARalpha.

  3. In conclusion, H8H8 haplotype combination of the PPARalpha may be advantageous for heat resistance traits in Chinese Holstein cattle.

  4. Data suggest that PPARalpha (but not PPARgamma (show PPARG Proteins)) is involved in vasorelaxation of ophthalmic artery in response to endocannabinoids (i.e., anandamide, palmitoylethanolamide); endothelium removal slightly decreases the response to endocannabinoids.

  5. Data from gene profiling experiments in bovine cell line support hypothesis that saturated long-chain fatty acids modulate ruminant lipid metabolism and expression of inflammation mediators with major effects induced via activation of PPARalpha.

  6. Dietary trans fatty acids may affect liver lipid metabolism in post-partum dairy cows through alterations in PPARalpha gene expression.

  7. Oxidized fataprevent an alcohol-induced triacylglycerol accumulation in rats possibly by upregulation of hepatic PPARalpha-responsive genes, whwereas conjugated linoleic acid does not.

  8. The results are consistent with the hypothesis that arachidonic acid acts via PPARalpha to increase PTGS2 (show PTGS2 Proteins) levels in bovine endometrial stromal cells.

Peroxisome Proliferator-Activated Receptor alpha (PPARA) Protein Profile

Protein Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined.

Alternative names and synonyms associated with Peroxisome Proliferator-Activated Receptor alpha (PPARA)

  • peroxisome proliferator-activated receptor alpha (LOC100136415)
  • peroxisome proliferative activated receptor, alpha (PPAR-ALPHA)
  • peroxisome proliferator activated receptor alpha (Ppara)
  • peroxisome proliferator activated receptor alpha (PPAR ALPHA)
  • peroxisome proliferator activated receptor alpha (ppara)
  • peroxisome proliferator-activated receptor alpha (PPARA)
  • peroxisome proliferator-activated receptor alpha (ppara)
  • 4933429D07Rik protein
  • AW742785 protein
  • hPPAR protein
  • LOC100136415 protein
  • nr1c1 protein
  • PPAR protein
  • PPAR-alpha protein
  • PPARALPHA protein
  • xppara protein
  • xPPARalpha protein

Protein level used designations for PPARA

peroxisome proliferator-activated receptor alpha , ppar alpha , peroxisome proliferator activated receptor alpha , peroxisome proliferator-activated receptor-alpha , nuclear receptor subfamily 1 group C member 1 , PPAR-alpha , peroxisome proliferative activated receptor, alpha , peroxisome proliferator-activated nuclear receptor alpha variant 3 , PPAR alpha , xPPAR alpha

GENE ID SPECIES
100136415 Salmo salar
100356422 Oryctolagus cuniculus
19013 Mus musculus
25747 Rattus norvegicus
443457 Ovis aries
100135604 Cavia porcellus
398843 Xenopus laevis
5465 Homo sapiens
403654 Canis lupus familiaris
496107 Xenopus laevis
374120 Gallus gallus
397239 Sus scrofa
100009308 Oryctolagus cuniculus
281992 Bos taurus
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