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PPARA Products

(Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Categories

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008].

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Featured PPARA Categories

PPARA Antibodies

High quality antibodies with extensive validation data.

PPARA ELISA Kits

Reliable ELISA kits for a wide range of species.

PPARA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPARA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken, Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
  • (5)
Cat. No. ABIN701620
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey
Application ELISA, FACS, ICC, IHC, WB
Validations
  • (5)
Cat. No. ABIN5542540
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cow, Dog, Golden Syrian Hamster, Mouse, Pig, Rat
Application IHC, ELISA, WB
Validations
  • (3)
  • (4)
Cat. No. ABIN105798
Quantity 100 μg
Datasheet Datasheet

Recommended PPARA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958498
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6958500
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative DNA-Binding ELISA
Validations
  • (2)
Cat. No. ABIN5690760
Quantity 96 tests
Datasheet Datasheet

Recommended PPARA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3094776
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133350
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315830
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PPARA products

Li, Xiong, Yan, Gao, Cheng, Wu, Liu, Zhang, Li, Wang, Fan, Zhao, Zhang, Tao: "Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-α pathway-dependent fatty acid oxidation." in: Theranostics, Vol. 10, Issue 12, pp. 5623-5640, (2021) (PubMed).

Kumar, Rani, Karns, Gandhi: "Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 3, pp. 3825-3840, (2019) (PubMed).

Krishnan, Baskaran, Thyagarajan: "Troglitazone activates TRPV1 and causes deacetylation of PPARγ in 3T3-L1 cells." in: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 2, pp. 445-453, (2019) (PubMed).

Ligresti, Caporarello, Meridew, Jones, Tan, Choi, Haak, Aravamudhan, Roden, Prakash, Lomberk, Urrutia, Tschumperlin: "CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis." in: JCI insight, Vol. 5, (2019) (PubMed).

Renu, K B, Parthiban, S, George, P B, Suman, V G, Arunachalam: "Elevated lipolysis in adipose tissue by doxorubicin via PPARα activation associated with hepatic steatosis and insulin resistance." in: European journal of pharmacology, Vol. 843, pp. 162-176, (2019) (PubMed).

Chiocchetti, Galiazzo, Tagliavia, Stanzani, Giancola, Menchetti, Militerno, Bernardini, Forni, Mandrioli: "Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia." in: Frontiers in veterinary science, Vol. 6, pp. 313, (2019) (PubMed).

Szalardy, Zadori, Bencsik, Vecsei, Klivenyi: "Unlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis." in: Neuroscience letters, Vol. 651, pp. 128-133, (2018) (PubMed).

Li, He, Xiao, Liu, Wang, Zhang: "Acetic Acid Influences BRL-3A Cell Lipid Metabolism via the AMPK Signalling Pathway." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 5, pp. 2021-2030, (2018) (PubMed).

Yang, Fu, Hu, Luo, Hu, Wang: "PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis." in: Experimental & molecular medicine, Vol. 50, Issue 1, pp. e431, (2018) (PubMed).

Galiazzo, Giancola, Stanzani, Fracassi, Bernardini, Forni, Pietra, Chiocchetti: "Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract." in: Histochemistry and cell biology, Vol. 150, Issue 2, pp. 187-205, (2018) (PubMed).

Synonyms and alternative names related to PPARA

peroxisome proliferator activated receptor alpha (PPARA), peroxisome proliferator-activated receptor alpha (LOC100136415), peroxisome proliferator activated receptor alpha L homeolog (ppara.L), peroxisome proliferator activated receptor alpha (Ppara), peroxisome proliferator activated receptor alpha (ppara), 4933429D07Rik, AW742785, hPPAR, LOC100136415, NR1C1, nr1c1, Nr1c1, PPAR, Ppar, PPAR-alpha, PPARalpha, PPARALPHA, xppara, xPPARalpha

Protein level used designations for PPARA

  • PPAR-alpha
  • nuclear receptor subfamily 1 group C member 1
  • peroxisome proliferative activated receptor, alpha
  • peroxisome proliferator-activated nuclear receptor alpha variant 3
  • PPAR alpha
  • peroxisome proliferator activated receptor alpha
  • peroxisome proliferator-activated receptor alpha
  • ppar alpha
  • xPPAR alpha
  • peroxisome proliferator-activated receptor-alpha
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