Browse our RORA Proteins (RORA)

Full name:
RAR-Related Orphan Receptor A Proteins (RORA)
On are 7 RAR-Related Orphan Receptor A (RORA) Proteins from 5 different suppliers available. Additionally we are shipping RORA Antibodies (157) and RORA Kits (3) and many more products for this protein. A total of 188 RORA products are currently listed.
9530021D13Rik, gb:dq017624, MGC146531, nmf267, Nr1f1, ROR1, ROR2, ROR3, rora2, RORalpha-B, RORalpha1, RZR-ALPHA, RZRA, sg, staggerer, tmgc26
list all proteins Gene Name GeneID UniProt
RORA 6095 P35398
Rat RORA RORA 300807  
RORA 19883 P51448

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RORA Proteins (RORA) by Origin

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More Proteins for RORA Interaction Partners

Human RAR-Related Orphan Receptor A (RORA) interaction partners

  1. Retinoid-related orphan receptor alpha-regulated development of the mouse cerebellum has a distinct critical period for (1) lengthening Purkinje cell (PC) primary dendrite stems and the eventual increase in the thickness of the molecular layer and (2) the establishment of mGluR (show GRM8 Proteins) signaling and associated removal of surplus climbing fibers from PCs.

  2. findings strongly suggest that CLDND1 is a direct RORalpha target

  3. TRIB3 (show TRIB3 Proteins) promotes acute promyelocytic leukemia (show PML Proteins) progression through stabilization of the oncoprotein PML (show PML Proteins)-RARalpha (show RARA Proteins) and inhibition of p53 (show TP53 Proteins)-mediated senescence.

  4. Retinoid-related orphan receptor alpha (RORalpha) reduction occurs in gastric cancer leading to the survival of tumor cells, which is attenuated by AMP-activated protein kinase (AMPK (show PRKAA2 Proteins)), therefore, both RORalpha and AMPK (show PRKAA1 Proteins) are potential targets for the intervention and therapy in gastric carcinoma.

  5. the RAR-related orphan receptor-a gene (RORA) and the Peroxisome Proliferator-Activated Receptor Gamma (show PPARG Proteins), Coactivator 1 Alpha gene (PPARGC1A or PGC-1alpha) were significantly associated with the Li response. Our results suggest genetic associations between Li response and these two close biological partners: PPARGC1A and RORA involved in circadian rhythms and bioenergetics processes in Li response

  6. The present study is to determine if any relation exists between RORA rs11639084 and rs4774388 gene polymorphisms on the individual susceptibility of multiple sclerosis.

  7. Association between RORA gene polymorphisms and the DSM-5 posttraumatic stress disorder symptoms in male earthquake survivors in China.

  8. The RORA intronic SNP rs11632098 was associated with greater odds of reporting depressive symptoms in older adults.

  9. A common SNP in the RORA gene (rs2899663) was associated with a 21% reduced odds of placental abruption.

  10. In a Han Chinese population, an association between RORA gene variation and depression personality trait was found.

Zebrafish RAR-Related Orphan Receptor A (RORA) interaction partners

  1. study reports cloning and expression pattern of zebrafish ROR alpha orthologues rora1 and rora2; both rora1 and rora2 are spatially expressed in the retina and tectum; expression of rora2 was further observed in the cerebellum

Mouse (Murine) RAR-Related Orphan Receptor A (RORA) interaction partners

  1. The deficiency of LXRalpha (show NR1H3 Proteins) decreased glucose uptake after MI, resulting in a metabolic shift that suppressed glucose metabolism, which was in association with adverse cardiac remodeling.

  2. Data suggest that inflammatory response in macrophages, white adipocytes, and white adipose tissue in obese mice, includes up-regulation of expression of Rora; in adipose tissue, overexpression of Rora or treatment with Rora agonist enhances expression of cytokines, promotes macrophage infiltration, up-regulates expression of genes involved in ER stress response, and enhances signaling seen in unfolded protein response.

  3. these findings reveal that RORalpha regulates macrophage M2 polarization via activation of AMPKalpha (show GRK4 Proteins)

  4. RORalpha regulates pathologic retinal angiogenesis by modulating SOCS3 (show SOCS3 Proteins)-dependent inflammation

  5. This study showed that spontaneous Rora mutations causing cerebellar pathology are impaired in motor functions during the neonatal period.

  6. the inhibition of NF-kappaB (show NFKB1 Proteins) by melatonin, but not that of NLRP3 (show NLRP3 Proteins), was blunted in RORalpha (sg/sg) mice, indicating that functional RORalpha transcription factor is necessary for the initiation of the innate immune response against inflammation.

  7. Rora induces the mRNA level of antioxidant enzymes, superoxide dismutase 2 (show SOD2 Proteins) and glutathione peroxidase 1 (show GPX1 Proteins), through the Rora response elements located in the upstream promoters of Sod2 (show SOD2 Proteins) and Gpx1 (show GPX1 Proteins).

  8. The nuclear receptors retinoic acid receptor (show RARA Proteins)-related orphan receptors-alpha and gammat (RORalpha and RORgammat) play critical roles in the development of TH17 cells.

  9. RORalpha is a transcriptional activator of insulin (show INS Proteins).

  10. Corl2/Skor2 has a role in regulating cerebellar Purkinje cell differentiation in a pathway involving RORalpha

RORA Protein Profile

Protein Summary

The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.

Alternative names and synonyms associated with RORA

  • RAR-related orphan receptor A (RORA)
  • RAR-related orphan receptor A (rora)
  • RAR-related orphan receptor A (Rora)
  • RAR-related orphan receptor A, paralog a (roraa)
  • RAR-related orphan receptor alpha (Rora)
  • 9530021D13Rik protein
  • gb:dq017624 protein
  • MGC146531 protein
  • nmf267 protein
  • Nr1f1 protein
  • ROR1 protein
  • ROR2 protein
  • ROR3 protein
  • rora2 protein
  • RORalpha-B protein
  • RORalpha1 protein
  • RZR-ALPHA protein
  • RZRA protein
  • sg protein
  • staggerer protein
  • tmgc26 protein

Protein level used designations for RORA

nuclear receptor ROR-alpha , RAR-related orphan receptor A , RAR-related orphan receptor alpha , ROR-alpha , nuclear receptor RZR-alpha , nuclear receptor subfamily 1 group F member 1 , retinoic acid receptor-related orphan receptor alpha , retinoid-related orphan receptor alpha , thyroid hormone nuclear receptor alpha variant 4 , transcription factor RZR-alpha , NR1F1-B , retinoid-related orphan receptor alpha 2 , rora , retinoid-related orphan receptor-alpha

747433 Pan troglodytes
780120 Xenopus (Silurana) tropicalis
6095 Homo sapiens
478328 Canis lupus familiaris
535597 Bos taurus
300807 Rattus norvegicus
564951 Danio rerio
19883 Mus musculus
415377 Gallus gallus
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