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Both AK7 (show AK7 Proteins) and full-length AK8 showed highest affinity for AMP (show APRT Proteins) with ATP as the phosphate donor, and proved to be more efficient in AMP (show APRT Proteins) phosphorylation as compared with the major cytosolic isoform AK1 (show AK1 Proteins)
In addition to AK1 (show AK1 Proteins) and AK2 (show AK2 Proteins), which we previously demonstrated are present in outer dense fibers (show ODF1 Proteins) and mitochondrial sheath of the mouse sperm tail, we show that another AK, AK8, is present in a third flagellar compartment, the axoneme.
Congenital hydrocephalus (show FOXC1 Proteins) and rhinosinusitis in Ak8 null mice
Adenylate kinase. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP (By similarity).
adenylate kinase 8
, ATP-AMP transphosphorylase 8
, putative adenylate kinase-like protein C9orf98
, Adenylate kinase isoenzyme 4, mitochondrial (ATP-AMP transphosphorylase)
, putative adenylate kinase-like protein C9orf98 homolog
, HypB, AroK, ADK and rho factor domain containing protein RGD1303144
, adenylate kinase-like protein