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Browse our C-MYC Proteins (MYC)

Full name:
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC)
On www.antibodies-online.com are 27 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteins from 7 different suppliers available. Additionally we are shipping C-MYC Antibodies (695) and C-MYC Kits (47) and many more products for this protein. A total of 798 C-MYC products are currently listed.
Synonyms:
AU016757, bHLHe39, C-MYC, CMyc, LOC100136746, mMyc, MRTL, MYC, Myc2, MYCC, Niard, Nird, RNCMYC, zc-myc
list all proteins Gene Name GeneID UniProt
MYC 24577 P09416
MYC 17869 P01108
MYC 4609 P01106

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C-MYC Proteins (MYC) by Origin

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Top referenced C-MYC Proteins

  1. Human C-MYC Protein expressed in Escherichia coli (E. coli) - ABIN1047412 : Battey, Moulding, Taub, Murphy, Stewart, Potter, Lenoir, Leder: The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. in Cell 1983 (PubMed)
    Show all 3 references for ABIN1047412

  2. Human C-MYC Protein expressed in HEK-293 Cells - ABIN2715370 : Garcia-Sanz, Quintanilla, Lafita, Moreno-Bueno, García-Gutierrez, Tabor, Varela, Shiio, Larsson, Portillo, Leon: Sin3b interacts with Myc and decreases Myc levels. in The Journal of biological chemistry 2014 (PubMed)
    Show all 3 references for ABIN2715370

More Proteins for C-MYC Interaction Partners

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. These results suggested that Notch2 (show NOTCH2 Proteins) signaling is linked to c-Myc expression and plays a key role in the regulation of MSC (show MSC Proteins) proliferation.

  2. this study demonstrates that the proto-oncoprotein Myc is a cell-intrinsic division timer, which regulates the extent of lymphocyte proliferative response

  3. Data show that expression of the Oct-4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins), Klf4 (show KLF4 Proteins), and c-Myc (OSKM) reprogramming factors induces Cyclin D1 (show CCND1 Proteins) expression, and the increased Cyclin D1 (show CCND1 Proteins) expression during reprogramming promotes continuing embryonic fibroblasts (MEFs) proliferation.

  4. demonstrate a critical link between Myc/Mycn (show MYCN Proteins) gene activity and glycolysis in spermatogonial stem cell self-renewal

  5. c-Myc gene expression in tumor tissues of mice treated I.V or IT with MSCs was down-regulated to 28.0% and 16.0% respectively compare to control groups. In conclusion, growth inhibition of breast tumors in mice due to MSC (show MSC Proteins) therapy is associated with modulation of c-Myc activation and angiogenesis markers.

  6. BRG1 (show SMARCA4 Proteins)/BRM (show SMARCA2 Proteins) and c-MYC have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (show RAB1A Proteins) in cancer.

  7. results indicate that the role of Myc in Hepatoblastoma pathogenesis is to impose mutually dependent changes in gene expression and metabolic reprogramming that are unattainable in non-transformed cells and that cooperate to maximize tumor growth

  8. The long intergenic non-coding RNA CCR492 functions as a let-7 competitive endogenous RNA to de-repress c-Myc expression and to promote cell transformation assisted by the constitutively active H-Ras (show HRAS Proteins).

  9. this study shows that siRNA-mediated depletion of Myc reduced the expression of IL-4 (show IL4 Proteins)-inducible genes in macrophages

  10. Findings identify BCL2A/A1 as a MYC target that can be induced prematurely during B cell development to aid expansion of otherwise cell-death-prone MYC transgenic pre-B cells.

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Apoptosis was also observed with myca expression; introduction of homozygous tp53 (show TP53 Proteins)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  2. MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. BRD4 (show BRD4 Proteins) positively regulates EZH2 (show EZH2 Proteins) transcription through upregulation of C-MYC, and is a novel promising target for pharmacologic treatment in transcriptional program intervention against this intractable disease.

  2. The mechanism of inhibition of c-Myc transcriptional activity by Miz-1 (show ZBTB17 Proteins) that binds c-Myc while competing for binding with Max has been described.

  3. c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production.

  4. Inhibition of mTORC1-mediated 4EBP1 (show EIF4EBP1 Proteins) phosphorylation leads to decreased expression of c-MYC and subsequent upregulation of the proapoptotic BCL2 (show BCL2 Proteins) family member PUMA (show BBC3 Proteins), whereas inhibition of mTORC2 (show CRTC2 Proteins) results in nuclear factor-kappaB-mediated expression of the Early Growth Response 1 (EGR1 (show EGR1 Proteins)) gene, which encodes a transcription factor that binds and transactivates the proapoptotic BCL2L11 (show BCL2L11 Proteins) locus encoding BIM (show BCL2L11 Proteins).

  5. feedback regulation between cMyc and p53 (show TP53 Proteins) is important for the T cell homeostasis.

  6. MYC and TEAD activity is able to stratify different breast cancer subtypes in large panels of breast cancer patients.

  7. Analysis of microarray data sets further demonstrated that MUC1 (show MUC1 Proteins) levels positively correlate with MYC expression in multiple myeloma progression

  8. c-Myc overexpression may increase sensitivity to poly(I:C)-induced tumor growth arrest and ROS (show ROS1 Proteins)-mediated apoptosis in neuroblastoma (show ARHGEF16 Proteins). This study demonstrates that c-Myc protein expression has an important role in TLR3 (show TLR3 Proteins)-induced innate immune responses.

  9. Prediction model based on the marker MYC determines progression risk in non-dysplastic Barrett's esophagus.

  10. INI1 (show SMARCB1 Proteins) re-expression suppresses cell proliferation and MYC-potentiated transformation.

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

C-MYC (MYC) Protein Profile

Protein Summary

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

  • v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
  • myelocytomatosis oncogene (Myc)
  • myelocytomatosis oncogene a (myca)
  • v-myc avian myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
  • AU016757 protein
  • bHLHe39 protein
  • C-MYC protein
  • CMyc protein
  • LOC100136746 protein
  • mMyc protein
  • MRTL protein
  • MYC protein
  • Myc2 protein
  • MYCC protein
  • Niard protein
  • Nird protein
  • RNCMYC protein
  • zc-myc protein

Protein level used designations for MYC

v-myc myelocytomatosis viral oncogene homolog , Avian myelocytomatosis viral (v-myc) oncogene homolog , myc proto-oncogene protein , myelocytomatosis viral oncogene homolog , proto-oncogene c-Myc , transcription factor p64 , v-myc avian myelocytomatosis viral oncogene homolog , c-myc proto-oncogene , C-Myc1 , c-Myc-A , cellular myelocytomatosis oncogene , cmyca , transcriptional regulator Myc-A , avian myelocytomatosis viral oncogene homolog , class E basic helix-loop-helix protein 39 , myc-related translation/localization regulatory factor , avian myelocytomatosis viral (v-myc) oncogene homolog , c-Myc , Proto-oncogene c-Myc , Transcription factor p64 , Myc proto-oncogene protein

GENE ID SPECIES
100136746 Oncorhynchus mykiss
24577 Rattus norvegicus
17869 Mus musculus
30686 Danio rerio
4609 Homo sapiens
420332 Gallus gallus
100327265 Oryctolagus cuniculus
403924 Canis lupus familiaris
448810 Sus scrofa
511077 Bos taurus
100379628 Felis catus
443447 Ovis aries
694626 Macaca mulatta
464393 Pan troglodytes
100407754 Callithrix jacchus
100972175 Pan paniscus
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