Browse our C-MYC Proteins (MYC)

Full name:
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC)
On www.antibodies-online.com are 27 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteins from 7 different suppliers available. Additionally we are shipping C-MYC Antibodies (696) and C-MYC Kits (47) and many more products for this protein. A total of 799 C-MYC products are currently listed.
Synonyms:
AU016757, bHLHe39, C-MYC, CMyc, LOC100136746, mMyc, MRTL, MYC, Myc2, MYCC, Niard, Nird, RNCMYC, zc-myc
list all proteins Gene Name GeneID UniProt
MYC 24577 P09416
MYC 17869 P01108
MYC 4609 P01106

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C-MYC Proteins (MYC) by Origin

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Top referenced C-MYC Proteins

  1. Human C-MYC Protein expressed in HEK-293 Cells - ABIN2715370 : Garcia-Sanz, Quintanilla, Lafita, Moreno-Bueno, García-Gutierrez, Tabor, Varela, Shiio, Larsson, Portillo, Leon: Sin3b interacts with Myc and decreases Myc levels. in The Journal of biological chemistry 2014 (PubMed)
    Show all 3 references for 2715370

  2. Human C-MYC Protein expressed in Escherichia coli (E. coli) - ABIN1047412 : Battey, Moulding, Taub, Murphy, Stewart, Potter, Lenoir, Leder: The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma. in Cell 1983 (PubMed)
    Show all 3 references for 1047412

More Proteins for C-MYC Interaction Partners

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. CRY2 (show CRY2 Proteins) and FBXL3 (show FBXL3 Proteins) cooperatively degrade c-MYC preventing the development of cancer.

  2. Data, including data from studies in cells from knockout mice, suggest that Prmt1 (show PRMT1 Proteins) activity was necessary for c-Myc binding to acetyltransferase p300 (show NOTCH1 Proteins) in myeloid cells; Prmt1 (show PRMT1 Proteins) inhibition decreases p300 (show NOTCH1 Proteins) recruitment to c-Myc target promoters and increased Hdac1 (show HDAC1 Proteins) recruitment. [Prmt1 (show PRMT1 Proteins), protein arginine N-methyltransferase 1 (show PRMT1 Proteins); c-Myc = Proto-Oncogene (show RAB1A Proteins) Proteins c-myc; Hdac1 (show HDAC1 Proteins) = histone deacetylase 1 (show HDAC1 Proteins)]

  3. MYC-dependent attenuation of GCLC (show GCLC Proteins) by miR (show MLXIP Proteins)-18a contributes to GSH depletion in vivo, and low GSH corresponds with increased sensitivity to oxidative stress in tumors.

  4. MYC mediates cell cycle re-entry of Trp53 (show TP53 Proteins)-altered hepatocytes via AURKA (show AURKA Proteins) binding.

  5. Modification of the tumor microenvironment in KRAS or c-MYC-induced ovarian cancer-associated peritonitis has been described.

  6. Myc can substitute for Notch1 (show NOTCH1 Proteins) in leukemogenesis

  7. interplay between MATalpha1, c-Myc, and Maf (show MAF Proteins) proteins, and their deregulation during chronic cholestasis may facilitate cholangiocarcinoma oncogenesis

  8. our results show how MYC drives the production of specific eicosanoids critical for lung cancer cell survival and proliferation

  9. Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf (show BMF Proteins) expression

  10. Data (including data from studies using transgenic mice) suggest that expression of c-Myc in liver can be correlated with progression, regression, and recurrence of hepatocellular carcinoma (using a specific mouse model).

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Apoptosis was also observed with myca expression; introduction of homozygous tp53 (show TP53 Proteins)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  2. MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Follicular lymphoma with MYC and BCL2 (show BCL2 Proteins) translocations, so-called double-hit follicular lymphoma (DH-FL), is part of the spectrum of double-hit high-grade lymphoma.

  2. Central nervous system posttransplant lymphoproliferative disorder is EBV positive, typically lacks p53 (show TP53 Proteins) and Myc expression by immunohistochemistry, and can present with numerous background T lymphocytes.

  3. NDRG1 (show NDRG1 Proteins) prevented the degradation of c-Myc through Skp2-mediated ubiquitination in tumor cells. NDRG1 (show NDRG1 Proteins) directly interacted with Skp2, and decreased phosphorylation of Skp2 through inactivation of CDK2 (show CDK2 Proteins).

  4. Results indicate that spliceosome inhibitors would be promising molecular target drugs in small cell lung cancer (SCLC) irrespective of the myc proto-oncogene protein (MYC) status.

  5. CRY2 (show CRY2 Proteins) and FBXL3 (show FBXL3 Proteins) cooperatively degrade c-MYC preventing the development of cancer.

  6. a critical role for JMJD1A (show KDM3A Proteins) in regulating proliferation and survival of prostate cancer cells by controlling c-Myc expression at transcriptional and post-translational levels

  7. This study demonstrates novel regulatory circuits involving miR (show MLXIP Proteins)-148a-3p/ERBB3 (show ERBB3 Proteins)/AKT2 (show AKT2 Proteins)/c-myc and DNMT1 (show DNMT1 Proteins) that controls bladder cancer progression, which may be useful in the development of more effective therapies against bladder cancer.

  8. The MUC1 (show MUC1 Proteins) oncoprotein was identified as the critical driver of (extracellular vesicle) EV-mediated myeloid-derived suppressor cells expansion in AML (show RUNX1 Proteins). microRNA miR34a acts as the regulatory mechanism by which MUC1 (show MUC1 Proteins) drives c-myc expression in AML (show RUNX1 Proteins) cells and EVs.

  9. Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 (show BCL2 Proteins) expression shows evidence of active B-cell receptor signaling

  10. Emetine induced cell death in primary refractory lymphoma cells with MYC rearrangement.

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

C-MYC (MYC) Protein Profile

Protein Summary

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

  • v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
  • myelocytomatosis oncogene (Myc)
  • myelocytomatosis oncogene a (myca)
  • v-myc avian myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
  • AU016757 protein
  • bHLHe39 protein
  • C-MYC protein
  • CMyc protein
  • LOC100136746 protein
  • mMyc protein
  • MRTL protein
  • MYC protein
  • Myc2 protein
  • MYCC protein
  • Niard protein
  • Nird protein
  • RNCMYC protein
  • zc-myc protein

Protein level used designations for MYC

v-myc myelocytomatosis viral oncogene homolog , Avian myelocytomatosis viral (v-myc) oncogene homolog , myc proto-oncogene protein , myelocytomatosis viral oncogene homolog , proto-oncogene c-Myc , transcription factor p64 , v-myc avian myelocytomatosis viral oncogene homolog , c-myc proto-oncogene , C-Myc1 , c-Myc-A , cellular myelocytomatosis oncogene , cmyca , transcriptional regulator Myc-A , avian myelocytomatosis viral oncogene homolog , class E basic helix-loop-helix protein 39 , myc-related translation/localization regulatory factor , avian myelocytomatosis viral (v-myc) oncogene homolog , c-Myc , Proto-oncogene c-Myc , Transcription factor p64 , Myc proto-oncogene protein

GENE ID SPECIES
100136746 Oncorhynchus mykiss
24577 Rattus norvegicus
17869 Mus musculus
30686 Danio rerio
4609 Homo sapiens
420332 Gallus gallus
100327265 Oryctolagus cuniculus
403924 Canis lupus familiaris
448810 Sus scrofa
511077 Bos taurus
100379628 Felis catus
443447 Ovis aries
694626 Macaca mulatta
464393 Pan troglodytes
100407754 Callithrix jacchus
100972175 Pan paniscus
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