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Browse our C-MYC Proteins (MYC)

Full name:
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC)
On www.antibodies-online.com are 34 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteins from 10 different suppliers available. Additionally we are shipping C-MYC Antibodies (936) and C-MYC Kits (61) and many more products for this protein. A total of 1069 C-MYC products are currently listed.
Synonyms:
AU016757, bHLHe39, C-MYC, CMyc, LOC100136746, mMyc, MRTL, MYC, Myc2, MYCC, Niard, Nird, RNCMYC, zc-myc
list all proteins Gene Name GeneID UniProt
MYC 24577 P09416
MYC 17869 P01108
MYC 4609 P01106

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C-MYC Proteins (MYC) by Origin

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Top referenced C-MYC Proteins

  1. Human C-MYC Protein expressed in Wheat germ - ABIN1311718 : Seo, Kim, Bae, Soh, Lee: Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1. in The Journal of biological chemistry 2008 (PubMed)

More Proteins for C-MYC Interaction Partners

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Data show that the reprogramming factors OCT4 (show POU5F1 Proteins), SOX2 (show SOX2 Proteins), KLF4 (show KLF4 Proteins), and MYC (OSKM) drive cells along two distinct and parallel pathways, one pluripotent and one endodermal.

  2. Expression of c-myc and ethanol-uptake synergistically accelerate the progression of Aalcoholic liver disease most likely due to loss of p53 (show TP53 Proteins)-dependent protection.

  3. our study provides valuable information on the molecular interactions between OSKM(Oct4 (show POU5F1 Proteins), Sox2 (show SOX2 Proteins), Klf4 (show KLF4 Proteins), and Myc) and cofactors and molecular mechanisms for the functional importance of Set1a in ESCs (show NR2E3 Proteins) and early development.

  4. ASCIZ (show ATMIN Proteins) and its target DYNLL1 (show DYNLL1 Proteins) are essential for the development and expansion of MYC-driven B cell lymphoma.

  5. Srebp-1 (show SREBF1 Proteins) interacts with c-Myc, facilitates its binding to downstream pluripotent targets.

  6. MCL-1 (show MCL1 Proteins) loss in early B-lymphoid progenitors delayed MYC-driven lymphomagenesis.

  7. Somatic cell transfer of c-Myc and Bcl-2 (show BCL2 Proteins) induces large-cell anaplastic medulloblastomas in mice.

  8. constitutive STAT5 (show STAT5A Proteins) binding to c-Myc super-enhancer might contribute to BRD2 (show BRD2 Proteins) maintenance and thus allow sustained expression of c-Myc in Ba/F3 cells transformed by STAT5 (show STAT5A Proteins)-1*6.

  9. These results identify c-Myc as a key controller of memory CD8 (show CD8A Proteins)(+) T cells from costimulatory signals.

  10. mice. In vitro assays revealed enhanced survival capacity of Myc-driven cells lacking FoxO3 (show FOXO3 Proteins), but no change in cell cycling was detected

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Apoptosis was also observed with myca expression; introduction of homozygous tp53 (show TP53 Proteins)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  2. MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Case Report: diffuse large B-cell lymphoma exhibiting MYC-IGH rearrangement and gain of BCL2 (show BCL2 Proteins).

  2. c-Myc Sustains Transformed Phenotype and Promotes Radioresistance of Embryonal Rhabdomyosarcoma Cell Lines

  3. Data show that expressions of histone deacetylase 6 protein (HDAC6) and c-myc protein are increased in fibroblasts transformed with activated K-ras protein.

  4. we demonstrate that patients with relapsed/refractory aggressive B-cell lymphoma and dual expression of MYC and BCL2 (show BCL2 Proteins) had particularly poor prognoses when treated uniformly with salvage chemotherapy, independently of other known risk factors.

  5. MYC is an oncoprotein whose expression is deregulated in multiple human cancers, identifying its critical downstream activities in tumors is of key importance for designing effective therapeutic strategies. [Review]

  6. Recurrent amplification of MYC and TNFRSF11B (show TNFRSF11B Proteins) in 8q24 is associated with poor survival in patients with gastric cancer.

  7. Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma.

  8. MYC gene family of transcription factors may be a targetable entity to test new therapies against, in particular, aurora kinase (show AURKA Proteins) inhibitors.Epigentic processes, such as gene promoter methylation and histone acetylation, may be candidate targets to test in small cell lung cancer (SCLC)

  9. These results indicate that miR (show MLXIP Proteins)-25 has anti-apoptosis roles in AGS (show JAG1 Proteins) cells, possibly via inhibiting FBXW7 (show FBXW7 Proteins) and thus promoting oncogenes, such as CCNE1 (show CCNE1 Proteins) and MYC.

  10. we demonstrated that upregulation of suprabasin activated the Wnt/b-catenin signaling pathway and led to nuclear localization of b-catenin and upregulation of Cyclin D1 and c-Myc. Together, our results suggest that suprabasin plays an important oncogenic role in promoting proliferation and tumorigenesis of esophageal squamous cell carcinoma .

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

C-MYC (MYC) Protein Profile

Protein Summary

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

  • v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
  • myelocytomatosis oncogene (Myc)
  • myelocytomatosis oncogene a (myca)
  • v-myc avian myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
  • AU016757 protein
  • bHLHe39 protein
  • C-MYC protein
  • CMyc protein
  • LOC100136746 protein
  • mMyc protein
  • MRTL protein
  • MYC protein
  • Myc2 protein
  • MYCC protein
  • Niard protein
  • Nird protein
  • RNCMYC protein
  • zc-myc protein

Protein level used designations for MYC

v-myc myelocytomatosis viral oncogene homolog , Avian myelocytomatosis viral (v-myc) oncogene homolog , myc proto-oncogene protein , myelocytomatosis viral oncogene homolog , proto-oncogene c-Myc , transcription factor p64 , v-myc avian myelocytomatosis viral oncogene homolog , c-myc proto-oncogene , C-Myc1 , c-Myc-A , cellular myelocytomatosis oncogene , cmyca , transcriptional regulator Myc-A , avian myelocytomatosis viral oncogene homolog , class E basic helix-loop-helix protein 39 , myc-related translation/localization regulatory factor , avian myelocytomatosis viral (v-myc) oncogene homolog , c-Myc , Proto-oncogene c-Myc , Transcription factor p64 , Myc proto-oncogene protein

GENE ID SPECIES
100136746 Oncorhynchus mykiss
24577 Rattus norvegicus
17869 Mus musculus
30686 Danio rerio
4609 Homo sapiens
420332 Gallus gallus
100327265 Oryctolagus cuniculus
403924 Canis lupus familiaris
448810 Sus scrofa
511077 Bos taurus
100379628 Felis catus
443447 Ovis aries
694626 Macaca mulatta
464393 Pan troglodytes
100407754 Callithrix jacchus
100972175 Pan paniscus
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