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Browse our C-MYC Proteins (MYC)

Full name:
V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) Proteins (MYC)
On www.antibodies-online.com are 33 V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) Proteins from 10 different suppliers available. Additionally we are shipping C-MYC Antibodies (666) and C-MYC Kits (64) and many more products for this protein. A total of 793 C-MYC products are currently listed.
Synonyms:
AU016757, bHLHe39, C-MYC, CMyc, LOC100136746, mMyc, MRTL, MYC, Myc2, MYCC, Niard, Nird, RNCMYC, zc-myc
list all proteins Gene Name GeneID UniProt
MYC 24577 P09416
MYC 17869 P01108
MYC 4609 P01106

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C-MYC Proteins (MYC) by Origin

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Top referenced C-MYC Proteins

  1. Human C-MYC Protein expressed in Wheat germ - ABIN1311718 : Seo, Kim, Bae, Soh, Lee: Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1. in The Journal of biological chemistry 2008 (PubMed)

More Proteins for C-MYC Interaction Partners

Mouse (Murine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. constitutive STAT5 (show STAT5A Proteins) binding to c-Myc super-enhancer might contribute to BRD2 (show BRD2 Proteins) maintenance and thus allow sustained expression of c-Myc in Ba/F3 cells transformed by STAT5 (show STAT5A Proteins)-1*6.

  2. These results identify c-Myc as a key controller of memory CD8 (show CD8A Proteins)(+) T cells from costimulatory signals.

  3. mice. In vitro assays revealed enhanced survival capacity of Myc-driven cells lacking FoxO3 (show FOXO3 Proteins), but no change in cell cycling was detected

  4. We concluded that HBx stabilizes Myc oncoprotein by inhibiting SCF (show KITLG Proteins)(Skp2) ubiquitin E3 ligase-mediated Myc ubiquitination, and the HBx-mediated Myc stabilization greatly contributes to viral oncogenesis

  5. FBP (show FUBP1 Proteins) helps to hold multiple physiologic processes to close tolerances, at least in part by constraining Myc expression.

  6. Constitutive ectopic expression of Myc resulted in rapid onset of a lethal myeloproliferative disorder with a median survival of 21 days.

  7. Strong selective advantage for leukemic transformation in the background of Stat5 (show STAT5A Proteins) deficient hematopoiesis was permissive for faster initiation of Myc-induced transformation to B (show TDO2 Proteins)-ALL.

  8. a switch from a Myc-dependent to a HIF1alpha (show HIF1A Proteins)-dependent transcriptional program may regulate the robust bioenergetic support for an inflammatory response, while sparing Myc-dependent proliferation.

  9. Study shows that ground-state embryonic stem cells express low Myc levels. Deletion of both c-myc and N-myc (show MYCN Proteins) activity strongly decreases transcription, splicing, and protein synthesis, leading to proliferation arrest; process is reversible and occurs without affecting pluripotency, suggesting that Myc-depleted stem cells enter a state of dormancy.

  10. The authors find that downstream of glycogen synthase kinase 3 (show GSK3a Proteins) inhibition, elevated cMyc and beta-catenin (show CTNNB1 Proteins) act in parallel to reduce transcription and DNA binding, respectively, of the transcriptional repressor Tcf7l1 (show TCF7L1 Proteins).

Zebrafish V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Apoptosis was also observed with myca expression; introduction of homozygous tp53 (show TP53 Proteins)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.

  2. MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.

Human V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. a An unexpected role of Myc is in inducing glutamine synthesis and suggest a molecular connection between DNA demethylation and glutamine metabolism in Mycdriven cancers.

  2. miR (show MLXIP Proteins)-23b/SP1 (show PSG1 Proteins)/c-myc forms a feed-forward loop supporting multiple myeloma cell growth

  3. Increased expression of c-myc is associated with glioblastoma.

  4. Immunohistochemical panel of CDX2, p120ctn, c-Myc, and Jagged1 proteins would be to distinguish between low/high grade dysplasia in histologically challenging cases of Barrett's esophagus.

  5. SMARCAL1 (show SMARCAL1 Proteins) negatively regulates c-myc transcription by altering the conformation of its promoter region during differentiation.

  6. Data show that Omomyc protein co-localized with proto-oncogene (show RAB1A Proteins) protein c-myc (c-Myc), protein arginine methyltransferase 5 (PRMT5 (show PRMT5 Proteins)) and histone H4 H4R3me2s-enriched chromatin domains.

  7. Increased c-myc is associated with invasiveness in Non-small Cell Lung Cancer.

  8. SerpinB3 (show SERPINB3 Proteins) indirectly increased the transcription of Myc through the induction of Yap (show YAP1 Proteins) pathway.

  9. IDO (show IDO1 Proteins), through GCN2 (show EIF2AK4 Proteins) kinase activation, downregulates the levels of TCRcomplex tchain and cMyc, resulting in the suppression of Tcell proliferation and a reduction in the levels of LDHA (show LDHA Proteins) and GLS2 (show GLS2 Proteins)

  10. study showed that De novo MYCyBCL2 double-hit BCP (show OPN1SW Proteins)-ALL is a rare disease that also occurs in pediatric and young adult patients and associated with complex karyotypes and poor prognosis. Younger patients may benefit from intensified chemotherapy.

Rabbit V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development

Cow (Bovine) V-Myc Myelocytomatosis Viral Oncogene Homolog (Avian) (MYC) interaction partners

  1. Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.

C-MYC (MYC) Protein Profile

Protein Summary

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

Alternative names and synonyms associated with C-MYC (MYC)

  • v-myc myelocytomatosis viral oncogene homolog (LOC100136746)
  • myelocytomatosis oncogene (Myc)
  • myelocytomatosis oncogene a (myca)
  • v-myc avian myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (MYC)
  • v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)
  • AU016757 protein
  • bHLHe39 protein
  • C-MYC protein
  • CMyc protein
  • LOC100136746 protein
  • mMyc protein
  • MRTL protein
  • MYC protein
  • Myc2 protein
  • MYCC protein
  • Niard protein
  • Nird protein
  • RNCMYC protein
  • zc-myc protein

Protein level used designations for MYC

v-myc myelocytomatosis viral oncogene homolog , Avian myelocytomatosis viral (v-myc) oncogene homolog , myc proto-oncogene protein , myelocytomatosis viral oncogene homolog , proto-oncogene c-Myc , transcription factor p64 , v-myc avian myelocytomatosis viral oncogene homolog , c-myc proto-oncogene , C-Myc1 , c-Myc-A , cellular myelocytomatosis oncogene , cmyca , transcriptional regulator Myc-A , avian myelocytomatosis viral oncogene homolog , class E basic helix-loop-helix protein 39 , myc-related translation/localization regulatory factor , avian myelocytomatosis viral (v-myc) oncogene homolog , c-Myc , Proto-oncogene c-Myc , Transcription factor p64 , Myc proto-oncogene protein

GENE ID SPECIES
100136746 Oncorhynchus mykiss
24577 Rattus norvegicus
17869 Mus musculus
30686 Danio rerio
4609 Homo sapiens
420332 Gallus gallus
100327265 Oryctolagus cuniculus
403924 Canis lupus familiaris
448810 Sus scrofa
511077 Bos taurus
100379628 Felis catus
443447 Ovis aries
694626 Macaca mulatta
464393 Pan troglodytes
100407754 Callithrix jacchus
100972175 Pan paniscus
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