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c-MYC Protein (AA 1-439) (GST tag)

MYC Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Catalog No. ABIN1311716
  • Target See all c-MYC (MYC) Proteins
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-439
    Origin
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 21
    • 4
    • 2
    • 1
    • 1
    Wheat germ
    Purification tag / Conjugate
    This c-MYC protein is labelled with GST tag.
    Application
    ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA)
    Purpose
    MYC (Human) Recombinant Protein (P01)
    Sequence
    MPLNVSFTNR NYDLDYDSVQ PYFYCDEEEN FYQQQQQSEL QPPAPSEDIW KKFELLPTPP LSPSRRSGLC SPSYVAVTPF SLRGDNDGGG GSFSTADQLE MVTELLGGDM VNQSFICDPD DETFIKNIII QDCMWSGFSA AAKLVSEKLA SYQAARKDSG SPNPARGHSV CSTSSLYLQD LSAAASECID PSVVFPYPLN DSSSPKSCAS QDSSAFSPSS DSLLSSTESS PQGSPEPLVL HEETPPTTSS DSEEEQEDEE EIDVVSVEKR QAPGKRSESG SPSAGGHSKP PHSPLVLKRC HVSTHQHNYA APPSTRKDYP AAKRVKLDSV RVLRQISNNR KCTSPRSSDT EENVKRRTHN VLERQRRNEL KRSFFALRDQ IPELENNEKA PKVVILKKAT AYILSVQAEE QKLISEEDLL RKRREQLKHK LEQLRNSCA
    Characteristics
    Human MYC full-length ORF ( ENSP00000259523, 1 a.a. - 439 a.a.) recombinant protein with GST-tag at N-terminal.
    Purification
    in vitro wheat germ expression system
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions
    For Research Use only
  • Buffer
    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -80 °C
    Storage Comment
    Best use within three months from the date of receipt of this protein.
  • Shoji, Suenaga, Kaneko, Islam, Alagu, Yokoi, Nio, Nakagawara: "NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells." in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 501-6, (2015) (PubMed).

    Smith, Womack: "A matrix approach to guide IHC-based tissue biomarker development in oncology drug discovery." in: The Journal of pathology, Vol. 232, Issue 2, pp. 190-8, (2013) (PubMed).

  • Target
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    Alternative Name
    MYC (MYC Products)
    Synonyms
    MRTL Protein, MYCC Protein, bHLHe39 Protein, c-Myc Protein, CMYC Protein, c-myc Protein, C-MYC Protein, LOC100136746 Protein, ARC Protein, B430311C09Rik Protein, MYC Protein, NOP Protein, Nop30 Protein, RNCMYC Protein, mMyc Protein, AU016757 Protein, Myc2 Protein, Niard Protein, Nird Protein, cmyc Protein, zc-myc Protein, c-myc II Protein, myc-B Protein, myc2 Protein, myc1 Protein, CMyc Protein, zgc:55680 Protein, CG10798 Protein, D-Myc Protein, DM Protein, DMYc Protein, Dm Protein, Dmel\CG10798 Protein, Dmyc Protein, EG:BACN5I9.1 Protein, anon-WO03040301.171 Protein, bHLHe57 Protein, c-MYC Protein, d-myc Protein, dMYC Protein, dMyc Protein, dMyc1 Protein, da Protein, dm Protein, dm/dMyc Protein, dm/myc Protein, dmyc Protein, dmyc1 Protein, l(1)G0139 Protein, l(1)G0354 Protein, l(1)G0359 Protein, myc Protein, MYC proto-oncogene, bHLH transcription factor Protein, v-myc myelocytomatosis viral oncogene homolog Protein, nucleolar protein 3 (apoptosis repressor with CARD domain) Protein, myelocytomatosis oncogene Protein, MYC proto-oncogene, bHLH transcription factor a Protein, MYC proto-oncogene, bHLH transcription factor L homeolog Protein, MYC proto-oncogene, bHLH transcription factor S homeolog Protein, v-myc myelocytomatosis viral oncogene homolog (avian) Protein, MYC proto-oncogene, bHLH transcription factor b Protein, CG10798 gene product from transcript CG10798-RB Protein, MYC Protein, LOC100136746 Protein, Nol3 Protein, Myc Protein, myca Protein, myc.L Protein, myc.S Protein, mycb Protein
    Background
    Full Gene Name: v-myc myelocytomatosis viral oncogene homolog (avian)
    Synonyms: bHLHe39,c-Myc
    Gene ID
    4609
    Pathways
    p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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