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Browse our anti-PML (PML) Antibodies

Full name:
anti-Promyelocytic Leukemia Antibodies (PML)
On www.antibodies-online.com are 129 Promyelocytic Leukemia (PML) Antibodies from 28 different suppliers available. Additionally we are shipping PML Proteins (8) and PML Kits (7) and many more products for this protein. A total of 153 PML products are currently listed.
Synonyms:
1200009E24Rik, AI661194, MYL, PML, PP8675, RGD1562602, RNF71, Trim19
list all antibodies Gene Name GeneID UniProt
PML 5371 P29590
PML 18854 Q60953
PML 315713  

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Most Popular Reactivities for anti-PML (PML) Antibodies

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anti-Human PML Antibodies:

anti-Mouse (Murine) PML Antibodies:

anti-Rat (Rattus) PML Antibodies:

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Top referenced anti-PML Antibodies

  1. Human Polyclonal PML Primary Antibody for ICC, IF - ABIN252967 : Wimmer, Schreiner, Everett, Sirma, Groitl, Dobner: SUMO modification of E1B-55K oncoprotein regulates isoform-specific binding to the tumour suppressor protein PML. in Oncogene 2010 (PubMed)
    Show all 21 references for ABIN252967

  2. Human Polyclonal PML Primary Antibody for EIA, IHC (p) - ABIN357734 : Kawai, Akira, Reed: ZIP kinase triggers apoptosis from nuclear PML oncogenic domains. in Molecular and cellular biology 2003 (PubMed)
    Show all 5 references for ABIN357734

  3. Human Monoclonal PML Primary Antibody for IF, WB - ABIN394032 : Vincenzi, Perrone, Santini, Grosso, Silletta, Frezza, Rossi, Russo, Rabitti, Gebbia, Badalamenti, Casali, Muda, Dei Tos, Tonini: PML down-regulation in soft tissue sarcomas. in Journal of cellular physiology 2010 (PubMed)
    Show all 5 references for ABIN394032

  4. Mouse (Murine) Monoclonal PML Primary Antibody for IF, IP - ABIN567791 : Sone, Hayashi, Tarui, Agata, Takeichi, Nakagawa: The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons. in Journal of cell science 2007 (PubMed)
    Show all 3 references for ABIN567791

  5. Human Polyclonal PML Primary Antibody for ELISA, WB - ABIN1583526 : Kolegraff, Nava, Helms, Parkos, Nusrat: Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling. in Molecular biology of the cell 2011 (PubMed)
    Show all 2 references for ABIN1583526

  6. Human Polyclonal PML Primary Antibody for ICC, IF - ABIN252968 : Kuroki, Ariumi, Ikeda, Dansako, Wakita, Kato: Arsenic trioxide inhibits hepatitis C virus RNA replication through modulation of the glutathione redox system and oxidative stress. in Journal of virology 2009 (PubMed)
    Show all 2 references for ABIN252968

  7. Human Polyclonal PML Primary Antibody for FACS, IF - ABIN389073 : Puccetti, Beissert, Güller, Li, Hoelzer, Ottmann, Ruthardt: Leukemia-associated translocation products able to activate RAS modify PML and render cells sensitive to arsenic-induced apoptosis. in Oncogene 2003 (PubMed)
    Show all 2 references for ABIN389073

  8. Human Polyclonal PML Primary Antibody for WB - ABIN2778427 : Eun, Lee, Hong, Kim, Lee, Kim, Sun, Kim: Hes6 controls cell proliferation via interaction with cAMP-response element-binding protein-binding protein in the promyelocytic leukemia nuclear body. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against PML Interaction Partners

Human Promyelocytic Leukemia (PML) interaction partners

  1. PML(nuclear localization signal -) was detected in primary acute promyelocytic leukemia (APL (show FASL Antibodies)), but not non-APL (show FASL Antibodies) cells. PML was localized to the nucleus, interacted with importin alpha (show KPNA4 Antibodies) in vivo, and co-localized in the PML nuclear bodies. PML(NLS (show ALDH1A2 Antibodies)-) was primarily localized in the cytoplasm and the interaction with importin alpha (show KPNA4 Antibodies) was lost

  2. These data suggest that CACUL1 is a novel regulator that negatively controls p53 (show TP53 Antibodies) activity through the regulation of PML SUMOylation.

  3. An HSV-1 protein, ICP0, can recognize individual host factors and target them differently for destruction. We identified elements that are important for the ICP0 E3 ubiquitin ligase (show MUL1 Antibodies) to differentially recognize two of its substrates, isoforms PML I and PML II.

  4. In line with these observations, rhesus monkey rhadinovirus infection resulted in rapid degradation of SP100 (show SP100 Antibodies), followed by degradation of PML and the loss of ND10 structures, whereas the protein levels of ATRX (show ATRX Antibodies) and DAXX (show DAXX Antibodies) remained constant.

  5. Taken together, these data show that the PML II isoform, through its various actions, has an overall negative effect on the human adenovirus 5 lifecycle.

  6. PML-RARa (show RARA Antibodies) bcr1 (show BCR Antibodies) fusion is not responsible for colorectal tumor development.

  7. PML nuclear bodies change in number and size in cells actively replicating Merkel cell polyomavirus proviral DNA.

  8. High PML expression is associated with hepatocellular carcinoma.

  9. This study demonstrated an important phosphorylated site of PML, which contributed to explore the role of PML in mitosis.

  10. PML acts as an effector of antiviral effects of IFN-beta (show IFNB1 Antibodies).

Mouse (Murine) Promyelocytic Leukemia (PML) interaction partners

  1. These findings suggest that the UBC9/PML/RNF4 axis plays a critical role as an important SUMO pathway in cardiac fibrosis. Modulating the protein levels of the pathway provides an attractive therapeutic target for the treatment of cardiac fibrosis and heart failure.

  2. PML contributes to the intrinsic restriction of HIV-1 infections in a cell type-dependent manner.

  3. both the PML-RARA (show RARA Antibodies)-driven competitive transplantation advantage and development of acute promyelocytic leukemia (APL (show FASL Antibodies)) required DNMT3A (show DNMT3A Antibodies)

  4. PML IV enhances global SUMO-1 (show SUMO1 Antibodies) conjugation, particularly that of p53 (show TP53 Antibodies), resulting in p53 (show TP53 Antibodies) stabilization and activation.

  5. our findings challenge the predominant model in the field and we propose that PML/RARA (show RARA Antibodies) initiates leukemia by subtly shifting cell fate decisions within the promyelocyte compartment.

  6. DNA-binding-defective PML/RARA (show RARA Antibodies) mutants could not repress the transcription of retinoic acid regulated genes.

  7. A novel antioxidative mechanism by which PML regulates cellular oxidant homeostasis by controlling complex II integrity and Nrf2 (show NFE2L2 Antibodies) activity and identified PML as an indispensable mediator of SFN (show SFN Antibodies) activity.

  8. pRB (show PGR Antibodies) can interact with PML specifically during senescence, suggesting that signaling events in senescence regulate assembly of PML and pRB (show PGR Antibodies) to establish heterochromatin and create a permanent cell cycle arrest.

  9. Data suggest that acute promyelocytic leukemia (APL (show FASL Antibodies)) differentiation is a default program triggered by clearance of promyelocytic leukemia-retinoic acid receptor alpha (show RARA Antibodies) fusion oncoprotein PML/RARA (show RARA Antibodies)-bound promoters.

  10. Our results add PML/TRIM19 to the growing list of TRIM (show TRAT1 Antibodies) proteins implicated in both intrinsic and innate immunity.

PML Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions\; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alternative names and synonyms associated with PML

  • promyelocytic leukemia (PML) antibody
  • promyelocytic leukemia (Pml) antibody
  • 1200009E24Rik antibody
  • AI661194 antibody
  • MYL antibody
  • PML antibody
  • PP8675 antibody
  • RGD1562602 antibody
  • RNF71 antibody
  • Trim19 antibody

Protein level used designations for PML

promyelocytic leukemia , probable transcription factor PML , promyelocytic leukemia protein , protein PML , probable transcription factor PML-like , RING finger protein 71 , promyelocytic leukemia, inducer of , tripartite motif protein TRIM19 , tripartite motif-containing protein 19

GENE ID SPECIES
415302 Gallus gallus
415304 Gallus gallus
453736 Pan troglodytes
700379 Macaca mulatta
100138545 Bos taurus
100388843 Callithrix jacchus
100607016 Nomascus leucogenys
5371 Homo sapiens
18854 Mus musculus
315713 Rattus norvegicus
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