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Browse our anti-PPP1R13B (PPP1R13B) Antibodies

Full name:
anti-Protein Phosphatase 1, Regulatory Subunit 13B Antibodies (PPP1R13B)
On are 53 Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Antibodies from 12 different suppliers available. Additionally we are shipping PPP1R13B Kits (6) and PPP1R13B Proteins (4) and many more products for this protein. A total of 69 PPP1R13B products are currently listed.
AI449786, ASPP1, AW545810, p53BP2-like, p85, pp2ca1, ppp1r13b, si:ch211-253p18.1, Tp53bp2, Trp53bp2, wu:fd42g12, zgc:153820
list all antibodies Gene Name GeneID UniProt
PPP1R13B 21981 Q62415
PPP1R13B 23368 Q96KQ4
PPP1R13B 314465  

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Most Popular Reactivities for anti-PPP1R13B (PPP1R13B) Antibodies

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anti-Mouse (Murine) PPP1R13B Antibodies:

anti-Human PPP1R13B Antibodies:

anti-Rat (Rattus) PPP1R13B Antibodies:

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Top referenced anti-PPP1R13B Antibodies

  1. Human Polyclonal PPP1R13B Primary Antibody for EIA, WB - ABIN401394 : Trigiante, Lu: ASPP [corrected] and cancer. in Nature reviews. Cancer 2006 (PubMed)
    Show all 5 references for ABIN401394

  2. Cow (Bovine) Polyclonal PPP1R13B Primary Antibody for WB - ABIN2783179 : Agirre, Román-Gómez, Jiménez-Velasco, Garate, Montiel-Duarte, Navarro, Vázquez, Zalacain, Calasanz, Heiniger, Torres, Minna, Prósper: ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia. in Oncogene 2006 (PubMed)

  3. Human Polyclonal PPP1R13B Primary Antibody for IHC, ELISA - ABIN1584021 : Matsumoto, Weckbecker, Cory: Antineoplastic effect of the combination of 2,3-dihydro-1H-pyrazole[2,3a]imidazole plus deoxyadenosine/erythro-9-(2-hydroxyl-3-nonyl)adenine in mice with L1210 leukemia cells. in Cancer communications 1990 (PubMed)

More Antibodies against PPP1R13B Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. After genotoxic stress, Aspp1 promotes hematopoietic stem cell (HSC (show FUT1 Antibodies)) cycling and induces p53 (show TP53 Antibodies)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 also attenuates HSC (show FUT1 Antibodies) self-renewal and accumulation of DNA damage in p53 (show TP53 Antibodies) null HSCs.

  2. Our study demonstrates a novel role for ASPP1 and ASPP2 (show TP53BP2 Antibodies) in the death of retinal ganglion cells.

  3. Aspp1 plays a crucial role in the initial assembly and function of lymphatic vessels during mouse development in a p53 (show TP53 Antibodies)-independent manner.

Human Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. ASPP1/2 interacted with centrosome linker protein (show LAT Antibodies) C (show PROC Antibodies)-Nap1 (show CEP250 Antibodies). Co-depletion of ASPP1 and ASPP2 (show TP53BP2 Antibodies) inhibited re-association of C-Nap1 (show CEP250 Antibodies) with centrosome at the end of mitosis.

  2. ASPP1 and ASPP2 (show TP53BP2 Antibodies) cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53 (show TP53 Antibodies).

  3. When the Px(T)PxR (show NR1I2 Antibodies) motif is deleted or mutated via insertion of a phosphorylation site mimic (T311D), PP-1c fails to bind to all three ASPP proteins, ASPP1, ASPP2 (show TP53BP2 Antibodies) and iASPP (show PPP1R13L Antibodies).

  4. the mRNA expression of ASPP1 and ASPP2 (show TP53BP2 Antibodies) was frequently dowregulated in tumor tissues, and this decreased significantly in samples expressing wild-type p53 (show TP53 Antibodies)

  5. ASPP1 promoter methylation may be associated with the malignant progression of non-small cell lung cancer, and ASPP1 expression promotes cellular apoptosis.

  6. The ability of ASPP1 to activate YAP (show YAP1 Antibodies) results in the decreased expression of LATS2 (show LATS2 Antibodies), which lowers the ability of p53 (show TP53 Antibodies) to induce p21 (show CDKN1A Antibodies), cell-cycle arrest and senescence.

  7. overexpression of ASPP1 rendered MCF-7 and MDA-MB231 breast cancer cells more sensitive to resveratrol-mediated apoptosis via the E2F (show E2F1 Antibodies) pathway

  8. Suggest that downregulation of ASPP1 by hypermethylation may be involved in the pathogenesis and progress of gestational trophoblastic disease, probably through its effect on apoptosis.

  9. Data show that Lats2 (show LATS2 Antibodies) and ASPP1 shunt p53 (show TP53 Antibodies) to proapoptotic promoters and promote the death of polyploid cells.

  10. Data show that ASPP1 enhances nuclear accumulation of YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies) and YAP (show YAP1 Antibodies)/TAZ (show TAZ Antibodies)-dependent transcriptional regulation.

PPP1R13B Antigen Profile

Antigen Summary

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Alternative names and synonyms associated with PPP1R13B

  • protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (PPP1R13B) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (ppp1r13b) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 13Bb (ppp1r13bb) antibody
  • protein phosphatase 1, regulatory subunit 13B (PPP1R13B) antibody
  • protein phosphatase 1, regulatory subunit 13B (ppp1r13b) antibody
  • protein phosphatase 1, regulatory subunit 13B (Ppp1r13b) antibody
  • AI449786 antibody
  • ASPP1 antibody
  • AW545810 antibody
  • p53BP2-like antibody
  • p85 antibody
  • pp2ca1 antibody
  • ppp1r13b antibody
  • si:ch211-253p18.1 antibody
  • Tp53bp2 antibody
  • Trp53bp2 antibody
  • wu:fd42g12 antibody
  • zgc:153820 antibody

Protein level used designations for PPP1R13B

protein phosphatase type 2C alpha 1 , protein phosphatase 1, regulatory (inhibitor) subunit 13B , apoptosis-stimulating protein of p53, 1 , apoptosis-stimulating of p53 protein 1-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53 binding protein, 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating protein of p53

30703 Danio rerio
423487 Gallus gallus
453193 Pan troglodytes
490874 Canis lupus familiaris
700432 Macaca mulatta
100020778 Monodelphis domestica
100060064 Equus caballus
100357525 Oryctolagus cuniculus
100380068 Xenopus (Silurana) tropicalis
100395359 Callithrix jacchus
100438788 Pongo abelii
100481667 Ailuropoda melanoleuca
100539199 Meleagris gallopavo
21981 Mus musculus
557278 Danio rerio
23368 Homo sapiens
496341 Xenopus laevis
511414 Bos taurus
314465 Rattus norvegicus
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