Browse our PPP1R13B Proteins (PPP1R13B)

Full name:
Protein Phosphatase 1, Regulatory Subunit 13B Proteins (PPP1R13B)
On are 4 Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) Proteins from 3 different suppliers available. Additionally we are shipping PPP1R13B Antibodies (62) and PPP1R13B Kits (2) and many more products for this protein. A total of 74 PPP1R13B products are currently listed.
AI449786, ASPP1, AW545810, p53BP2-like, p85, pp2ca1, ppp1r13b, si:ch211-253p18.1, Tp53bp2, Trp53bp2, wu:fd42g12, zgc:153820
list all proteins Gene Name GeneID UniProt
PPP1R13B 21981 Q62415
PPP1R13B 23368 Q96KQ4
Rat PPP1R13B PPP1R13B 314465  

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PPP1R13B Proteins (PPP1R13B) by Origin

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More Proteins for PPP1R13B Interaction Partners

Mouse (Murine) Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. After genotoxic stress, Aspp1 promotes hematopoietic stem cell (HSC (show FUT1 Proteins)) cycling and induces p53 (show TP53 Proteins)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 also attenuates HSC (show FUT1 Proteins) self-renewal and accumulation of DNA damage in p53 (show TP53 Proteins) null HSCs.

  2. Our study demonstrates a novel role for ASPP1 and ASPP2 (show TP53BP2 Proteins) in the death of retinal ganglion cells.

  3. Aspp1 plays a crucial role in the initial assembly and function of lymphatic vessels during mouse development in a p53 (show TP53 Proteins)-independent manner.

Human Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B) interaction partners

  1. Increased expression of p53 (show TP53 Proteins) and ASPP1 and downregulation of iASPP (show PPP1R13L Proteins).

  2. ASPP1/2-PP1 (show PPA1 Proteins) complexes are required for chromosome segregation and kinetochore-microtubule attachments.

  3. ASPP1/2 interacted with centrosome linker protein C-Nap1. Co-depletion of ASPP1 and ASPP2 inhibited re-association of C-Nap1 with centrosome at the end of mitosis.

  4. ASPP1 and ASPP2 (show TP53BP2 Proteins) cooperate with oncogenic RAS to enhance the transcription and apoptotic function of p53 (show TP53 Proteins).

  5. When the Px(T)PxR (show NR1I2 Proteins) motif is deleted or mutated via insertion of a phosphorylation site mimic (T311D), PP-1c fails to bind to all three ASPP proteins, ASPP1, ASPP2 (show TP53BP2 Proteins) and iASPP (show PPP1R13L Proteins).

  6. the mRNA expression of ASPP1 and ASPP2 (show TP53BP2 Proteins) was frequently dowregulated in tumor tissues, and this decreased significantly in samples expressing wild-type p53 (show TP53 Proteins)

  7. ASPP1 promoter methylation may be associated with the malignant progression of non-small cell lung cancer, and ASPP1 expression promotes cellular apoptosis.

  8. The ability of ASPP1 to activate YAP (show YAP1 Proteins) results in the decreased expression of LATS2, which lowers the ability of p53 (show TP53 Proteins) to induce p21 (show CDKN1A Proteins), cell-cycle arrest and senescence.

  9. overexpression of ASPP1 rendered MCF-7 and MDA-MB231 breast cancer cells more sensitive to resveratrol-mediated apoptosis via the E2F (show E2F1 Proteins) pathway

  10. Suggest that downregulation of ASPP1 by hypermethylation may be involved in the pathogenesis and progress of gestational trophoblastic disease, probably through its effect on apoptosis.

PPP1R13B Protein Profile

Protein Summary

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.

Alternative names and synonyms associated with PPP1R13B

  • protein phosphatase, Mg2+/Mn2+ dependent, 1Ab (ppm1ab)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (PPP1R13B)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (ppp1r13b)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b)
  • protein phosphatase 1, regulatory (inhibitor) subunit 13Bb (ppp1r13bb)
  • protein phosphatase 1, regulatory subunit 13B (PPP1R13B)
  • protein phosphatase 1, regulatory subunit 13B (ppp1r13b)
  • protein phosphatase 1, regulatory subunit 13B (Ppp1r13b)
  • AI449786 protein
  • ASPP1 protein
  • AW545810 protein
  • p53BP2-like protein
  • p85 protein
  • pp2ca1 protein
  • ppp1r13b protein
  • si:ch211-253p18.1 protein
  • Tp53bp2 protein
  • Trp53bp2 protein
  • wu:fd42g12 protein
  • zgc:153820 protein

Protein level used designations for PPP1R13B

protein phosphatase type 2C alpha 1 , protein phosphatase 1, regulatory (inhibitor) subunit 13B , apoptosis-stimulating protein of p53, 1 , apoptosis-stimulating of p53 protein 1-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53 binding protein, 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating protein of p53

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100060064 Equus caballus
100357525 Oryctolagus cuniculus
100380068 Xenopus (Silurana) tropicalis
100395359 Callithrix jacchus
100438788 Pongo abelii
100481667 Ailuropoda melanoleuca
100539199 Meleagris gallopavo
21981 Mus musculus
557278 Danio rerio
23368 Homo sapiens
496341 Xenopus laevis
511414 Bos taurus
314465 Rattus norvegicus
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