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anti-Human TRIM29 Antibodies:
anti-Mouse (Murine) TRIM29 Antibodies:
anti-Rat (Rattus) TRIM29 Antibodies:
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Human Polyclonal TRIM29 Primary Antibody for IHC (fro), ELISA - ABIN537436
Katkoori, Shanmugam, Jia, Vitta, Sthanam, Callens, Messiaen, Chen, Zhang, Bumpers, Samuel, Manne: Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas. in PLoS ONE 2012
Human Polyclonal TRIM29 Primary Antibody for ELISA, IHC - ABIN4362410
Kosaka, Inoue, Ohmachi, Yokoe, Matsumoto, Mimori, Tanaka, Watanabe, Mori: Tripartite motif-containing 29 (TRIM29) is a novel marker for lymph node metastasis in gastric cancer. in Annals of surgical oncology 2007
Human Polyclonal TRIM29 Primary Antibody for ELISA, IHC - ABIN4362411
Wang, Heidt, Lee, Yang, Logsdon, Zhang, Fearon, Ljungman, Simeone: Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. in Cancer cell 2009
Data show that TRIM29 promotes tumor progression by activating Wnt (show WNT2 Antibodies)/beta-Catenin (show CTNNB1 Antibodies) signaling.
This study establishes TRIM29 as a hypoxia-induced tumor suppressor gene and provides a novel molecular mechanism for ATM (show ATM Antibodies)-dependent breast cancer suppression.
Upregulation of TRIM29 is associated with thyroid cancer.
miR (show MLXIP Antibodies)-761 acts as an oncogene (show RAB1A Antibodies) in triple-negative breast cancer. This mode of action can, at least partially, be ascribed to the down-regulation of its target TRIM29.
Silencing of TRIM29 significantly inhibited the migration and invasion ability of CRC (show CALR Antibodies) cells.
Findings established a role for ATDC/TRIM29 as a robust pathogenic driver of bladder cancer development, identified downstream effector pathways, and implicated ATDC as a candidate biomarker and therapeutic target.
define a novel function for ATDC in the RNF8 (show RNF8 Antibodies)-mediated DNA damage response and implicate RNF8 (show RNF8 Antibodies) binding as a key determinant of the radioprotective function of ATDC
Results suggest that TRIM29 functions as an oncogene (show RAB1A Antibodies) in gastric cancer and is regulated by miR (show MLXIP Antibodies)-185.
TRIM29 functions as a scaffold protein (show HOMER1 Antibodies) to assemble DNA repair proteins into chromatin followed by efficient activation of DNA damage response.
These findings suggest that TRIM29 regulates the p63 (show RPE65 Antibodies)-mediated pathway and the behavior of cervical cancer cells.
this study shows that deletion of TRIM29 enhanced macrophage production of type I interferons and protected mice from infection with influenza virus, while challenge of Trim29-/- mice with Haemophilus influenzae resulted in lethal lung inflammation due to massive production of proinflammatory cytokines by macrophages
ATDC up-regulates CD44 (show CD44 Antibodies) in mouse and human PanIN lesions via activation of beta-catenin (show CTNNB1 Antibodies) signaling, leading to the induction of an epithelial-to-mesenchymal transition (EMT (show ITK Antibodies)) phenotype characterized by expression of Zeb1 (show ZEB1 Antibodies) and Snail1 (show SNAI1 Antibodies).
Histone deacetylase 9 (HDAC9 (show HDAC9 Antibodies)) regulates the functions of the ATDC (TRIM29) protein
ATDC increases cell proliferation via inhibition of p53 (show TP53 Antibodies) nuclear activities.
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.
ataxia telangiectasia group D-associated protein
, ataxia-telangiectasia group D-associated protein
, tripartite motif protein TRIM29
, tripartite motif-containing 29
, tripartite motif-containing protein 29
, tripartite motif protein 29
, tripartite motif-containing protein 29-like