Browse our anti-Carboxypeptidase E (CPE) Antibodies

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anti-Carboxypeptidase E Antibodies (CPE)
On are 89 Carboxypeptidase E (CPE) Antibodies from 25 different suppliers available. Additionally we are shipping Carboxypeptidase E Proteins (28) and Carboxypeptidase E Kits (17) and many more products for this protein. A total of 142 Carboxypeptidase E products are currently listed.
CARBE, CPE, Cph, Cph-1, Cph1, fat, R74677, si:ch211-198g9.2, zgc:85981

Most Popular Reactivities for anti-Carboxypeptidase E (CPE) Antibodies

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Top referenced anti-Carboxypeptidase E Antibodies

  1. Human Monoclonal CPE Primary Antibody for ELISA - ABIN1995595 : Cool, Normant, Shen, Chen, Pannell, Zhang, Loh: Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice. in Cell 1997 (PubMed)
    Show all 5 references for 1995595

  2. Human Monoclonal CPE Primary Antibody for IF, IP - ABIN968159 : Manser, Fernandez, Loo, Goh, Monfries, Hall, Lim: Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro. in The Biochemical journal 1990 (PubMed)
    Show all 4 references for 968159

  3. Human Polyclonal CPE Primary Antibody for ELISA, WB - ABIN1534734 : Utsunomiya, Ohagi, Sanke, Tatsuta, Hanabusa, Nanjo: Organization of the human carboxypeptidase E gene and molecular scanning for mutations in Japanese subjects with NIDDM or obesity. in Diabetologia 1998 (PubMed)
    Show all 2 references for 1534734

  4. Human Polyclonal CPE Primary Antibody for WB - ABIN392011 : Oiso, Takeda, Futagawa, Miura, Kuchiiwa, Nishida, Ikeda, Kariyazono, Watanabe, Yamada: Contactin-associated protein (Caspr) 2 interacts with carboxypeptidase E in the CNS. in Journal of neurochemistry 2009 (PubMed)

  5. Cow (Bovine) Polyclonal CPE Primary Antibody for IHC, WB - ABIN2787685 : Wang, Zhang, Yang, Zhu, Wang, Chen, Cao, Huang, Ma, Jia: Association of human carboxypeptidase E exon5 gene polymorphisms with angiographical characteristics of coronary atherosclerosis in a Chinese population. in Acta pharmacologica Sinica 2008 (PubMed)

More Antibodies against Carboxypeptidase E Interaction Partners

Human Carboxypeptidase E (CPE) interaction partners

  1. CPE through its N'-terminal sequence, forms aggregates with Wnt3a (show WNT3A Antibodies) and possible endoplasmic reticulum (ER) stress leading to its loss of function.

  2. we have identified a novel SNP in the CPE gene which results in the loss of its neuroprotective function in cells and may confer neurological disorders in humans

  3. High-level CPE [ carboxypeptidase E] expression was associated with a poor prognosis in early-stage cervical cancer. CPE may serve as a biomarker for predicting PLNM [ pelvic lymph node metastasis ] and survival in these patients.

  4. Low carboxypeptidase E expression is associated with recurrence in early-stage hepatocellular carcinoma.

  5. Down-expression of liver carboxypeptidase E may reduce the secretion of serum cholecystokinin (show CCK Antibodies) and contribute to the formation of cholesterol gallstone.

  6. Downregulation of CPE regulates cell proliferation and chemosensitivity in pancreatic cancer.

  7. Disruption of insulin receptor (IR (show INSR Antibodies)) expression in beta cells has a direct impact on the expression of the convertase enzyme carboxypeptidase E (CPE) by inhibition of the eukaryotic translation initiation factor (show EIF2A Antibodies) Eif4g1 (show EIF4G1 Antibodies).

  8. Upregulation of CPE promotes cell proliferation and tumorigenicity in colorectal cancer.

  9. Data suggest that splice variant of carboxypeptidase E (CPE-DeltaN) that CPE-DeltaN expression might be a potential prognostic marker for colorectal cancer patients.

  10. CPE is essential in the process and targeting of neuropeptides and neurotrophins, its participation in the pathological progression of Alzheimer's disease may be suggested

Mouse (Murine) Carboxypeptidase E (CPE) interaction partners

  1. we show by RNA silencing that CPE and SgIII (show SCG3 Antibodies) play a synergistic role in the trafficking of POMC (show POMC Antibodies) to granules of the regulated secretory pathway in AtT20 cells

  2. An anti-inflammatory role of CPE in the intestine by influencing local cytokine levels and thus regulating the migration of myeloid immune cells into the mucosa.

  3. This study shown that NF-alpha1-mediated upregulation of hippocampal FGF2 (show FGF2 Antibodies) and neurogenesis prevents an onset of chronic stress-induced depressive-like behavior

  4. The neuroprotective effect of CPE-DeltaN against neuronal glutamate (show GRIN1 Antibodies) neurotoxicity was mediated by secreted FGF2 (show FGF2 Antibodies).

  5. Carboxypeptidase E is an important modulator of RANKL (show TNFSF11 Antibodies)-induced osteoclast differentiation.

  6. Report the effects of ovalbumin (show OVA Antibodies) sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice.

  7. Disruption of insulin receptor (IR (show INSR Antibodies)) expression in beta cells has a direct impact on the expression of the convertase enzyme carboxypeptidase E (CPE) by inhibition of the eukaryotic translation initiation factor (show EIF2A Antibodies) Eif4g1 (show EIF4G1 Antibodies).

  8. This study has identified CPE as a new neurotrophic factor (show NTF3 Antibodies) that can protect neurons against degeneration.

  9. Data suggests that CPE plays critical role in neuroprotection/allostasis in hippocampal neurons during mild chronic stress; up-regulation of CPE and BCL2 (B cell leukemia/lymphoma 2) expression is possibly mediated by glucocorticoids.

  10. There are multiple mechanisms for sorting proglucagon (show GCG Antibodies) to the regulated secretory pathway, including a role for carboxypeptidase E in pancreatic alpha cells, initial cleavage at K70R71 and multiple sorting signals.

Carboxypeptidase E (CPE) Antigen Profile

Antigen Summary

This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.

Alternative names and synonyms associated with Carboxypeptidase E (CPE)

  • carboxypeptidase E (CPE) antibody
  • carboxypeptidase E (cpe) antibody
  • carboxypeptidase E (Cpe) antibody
  • CARBE antibody
  • CPE antibody
  • Cph antibody
  • Cph-1 antibody
  • Cph1 antibody
  • fat antibody
  • R74677 antibody
  • si:ch211-198g9.2 antibody
  • zgc:85981 antibody

Protein level used designations for CPE

carboxypeptidase E , carboxypeptidase E preproprotein , carboxypeptidase E-like , CPH , carboxypeptidase H , cobalt-stimulated chromaffin granule carboxypeptidase , enkephalin convertase , insulin granule-associated carboxypeptidase , prohormone-processing carboxypeptidase

443028 Ovis aries
475492 Canis lupus familiaris
708881 Macaca mulatta
100127580 Xenopus (Silurana) tropicalis
100397838 Callithrix jacchus
100458397 Pongo abelii
1363 Homo sapiens
280753 Bos taurus
12876 Mus musculus
25669 Rattus norvegicus
407979 Danio rerio
100158368 Xenopus laevis
422424 Gallus gallus
100037304 Sus scrofa
461592 Pan troglodytes
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