CPE Products
(Carboxypeptidase E (CPE))
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This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq, Jul 2008].
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Featured CPE Categories
CPE Antibodies
High quality antibodies with extensive validation data.
CPE ELISA Kits
Reliable ELISA kits for a wide range of species.
CPE Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CPE Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (4)
Cat. No.
ABIN7435985
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (3)
Cat. No.
ABIN6257071
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN2856267
Quantity
100 μL
Datasheet
Datasheet
Recommended CPE ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (6)
Cat. No.
ABIN6730971
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN5564566
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882088
Quantity
96 tests
Datasheet
Datasheet
Recommended CPE Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350184
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122142
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3090748
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CPE products
: "Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux." in: Oncotarget, Vol. 8, Issue 40, pp. 67567-67591, (2017) (PubMed).: "Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway." in: Oncogene, Vol. 32, Issue 23, pp. 2836-47, (2013) (PubMed).
: "Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice." in: Cell, Vol. 88, Issue 1, pp. 73-83, (1997) (PubMed).
: "Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 10, pp. 5314-9, (1997) (PubMed).
: "The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing." in: The Journal of biological chemistry, Vol. 271, Issue 11, pp. 6077-83, (1996) (PubMed).
: "Human carboxypeptidase E. Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro." in: The Biochemical journal, Vol. 267, Issue 2, pp. 517-25, (1990) (PubMed).
Synonyms and alternative names related to CPE
carboxypeptidase E (CPE), carboxypeptidase E (cpe), carboxypeptidase E (Cpe), carboxypeptidase E L homeolog (cpe.L), CARBE, CPE, CPH, Cph, Cph-1, Cph1, fat, R74677, si:ch211-198g9.2, zgc:85981Protein level used designations for CPE
- carboxypeptidase E
- carboxypeptidase E preproprotein
- carboxypeptidase E-like
- CPH
- carboxypeptidase H
- cobalt-stimulated chromaffin granule carboxypeptidase
- enkephalin convertase
- insulin granule-associated carboxypeptidase
- prohormone-processing carboxypeptidase
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