Browse our GATA4 Proteins (GATA4)

Full name:
GATA Binding Protein 4 Proteins (GATA4)
On are 11 GATA Binding Protein 4 (GATA4) Proteins from 6 different suppliers available. Additionally we are shipping GATA4 Antibodies (192) and GATA4 Kits (42) and many more products for this protein. A total of 252 GATA4 products are currently listed.
ASD2, gata, Gata-4, gata4, MGC81427, VSD1, xGATA-4, xgata4
list all proteins Gene Name GeneID UniProt
GATA4 2626 P43694
GATA4 14463 Q08369
GATA4 54254 P46152

Show all synonyms

GATA4 Proteins (GATA4) by Origin

Select your origin of interest

More Proteins for GATA4 Interaction Partners

Xenopus laevis GATA Binding Protein 4 (GATA4) interaction partners

  1. Data show that GATA4 or 6 regulate both cardiogenic potential and subsequent cardiomyocyte differentiation but that GATA5 is involved in regulating cardiomyocyte differentiation.

  2. Results describe the expression of GATA4 and 6 during gastrulation and their function in migratory behaviour.

  3. The data demonstrate that KLF13 (show KLF13 Proteins) is an important component of the transcription network required for heart development and suggest that KLF13 (show KLF13 Proteins) is a GATA-4 modifier

  4. Data show that GATA4 knockdown only affects cardiac marker expression in the absence of either GATA5 or GATA6, suggesting redundancy in this family during myocardial development.

Rabbit GATA Binding Protein 4 (GATA4) interaction partners

  1. These results indicate a higher capacity of adipose-derived than bone marrow-derived mesenchymal stem cells to express GATA4.

Human GATA Binding Protein 4 (GATA4) interaction partners

  1. This study attempts to correlate the pattern of intronic variants of GATA4 gene which might provide new insights to unravel the possible molecular etiology of congenital heart disease.

  2. GATA4 induces autocrine BMP2 (show BMP2 Proteins) signaling in endothelial cells

  3. study identified a novel mutation in GATA4 that likely contributed to the Congenital Heart Disease in this family. This finding expanded the spectrum of GATA4 mutations and underscored the pathogenic correlation between GATA4 mutations and Congenital Heart Disease.

  4. Hence, the variant distribution of NKX2-5 (show NKX2-5 Proteins), GATA4 and TBX5 (show TBX5 Proteins) are tightly associated with particular Congenital heart disease subtypes. Further structure-modelling analysis revealed that these mutated amino acid residuals maintain their DNA-binding ability and structural stability

  5. Findings suggest that a single introduction of the three cardiomyogenic transcription factor (GATA4, cand TBX5 (show TBX5 Proteins))genes using polyethyleneimine (PEI)-based transfection is sufficient for transdifferentiation of adipose-derived stem cells (hADSCs) towards the cardiomyogenic lineage.

  6. Meta-analysis suggested that GATA4 99 G>T and 487 C>T mutations may not be related to the incidence of congenital heart disease (CHD (show CHDH Proteins)). However, GATA4 354 A>C mutation was significantly associated with CHD (show CHDH Proteins) risk.

  7. common variants in 3'UTR of the GATA4 gene jointly interact, affecting the congenital heart disease susceptibility, probably by altering microRNA posttranscriptional regulation

  8. Our studies suggest that GATA5 (show GATA5 Proteins) but especially GATA4 are main contributors to SCN5A (show SCN5A Proteins) gene expression, thus providing a new paradigm of SCN5A (show SCN5A Proteins) expression regulation that may shed new light into the understanding of cardiac disease.

  9. GATA4-G296S mutation led to failure of GATA4 and TBX5 (show TBX5 Proteins)-mediated repression at non-cardiac genes and enhanced open chromatin states at endothelial/endocardial promoters. These results reveal how disease-causing missense mutations can disrupt transcriptional cooperativity, leading to aberrant chromatin states and cellular dysfunction, including those related to morphogenetic defects.

  10. We confirmed the significance of the HNF1B (show HNF1B Proteins) and GATA4 hypermethylation with emphasis on the need of selecting the most relevant sites for analysis. We suggest selected CpGs to be further examined as a potential positive prognostic factor.

Pig (Porcine) GATA Binding Protein 4 (GATA4) interaction partners

  1. investigation of genes regulated by GATA4, GATA6 (show GATA6 Proteins), and both in combination: studies in granulosa cells primed for luteinization

  2. GATA-4 and C/EBPbeta (show CEBPB Proteins) are both required for FSH (show BRD2 Proteins) +/- IGF-I (show IGF1 Proteins) stimulation of the porcine steroidogenic acute regulatory protein (show STAR Proteins) gene promoter in homologous granulosa cell cultures.

  3. The altered ratio of GATA4 to GATA6 (show GATA6 Proteins) after ovulation may allow GATA6 (show GATA6 Proteins) to enhance STAR mRNA accumulation.

Mouse (Murine) GATA Binding Protein 4 (GATA4) interaction partners

  1. Mechanistically, decreased GATA4 levels caused the downregulation of several pro-regenerative genes (among them interleukin-13 (show IL13 Proteins), Il13 (show IL13 Proteins)) in the myocardium.

  2. GATA4 acts as master regulator of hepatic microvascular specification and acquisition of organ-specific vascular competence, which are indispensable for liver development.

  3. study provides novel insights into the role of WT1 (show WT1 Proteins) and GATA4 during the sex differentiation phase and represents an approach that can be applied to assess other proteins with as yet unknown functions during gonadal development

  4. we have identified a distinct lineage of adult HSCs characterized by its derivation of progenitors where Gata4 expression is activated by a specific enhancer. Most adult HSCs belonging to this lineage probably originate in the placenta.

  5. Histone acetylation/methylation and DNA methylation (show HELLS Proteins) were both involved in regulating GATA4 expression, but Nkx2.5 (show NKX2-5 Proteins) expression was not regulated by DNA methylation (show HELLS Proteins). These three modifications had high correlation with each other during regulation of GATA4 and produced a regulation loop at the GATA4 promoter.

  6. GATA4 acts as a negative regulator of Bsp (show KLK6 Proteins) expression in osteoblasts.

  7. Detailed analysis of specific lineage markers expression showed selective downregulation of endoderm markers in REST-null cells, thus contributing to a loss of cardiogenic signals. REST regulates cardiac differentiation of ESCs (show NR2E3 Proteins) by negatively regulating the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway and positively regulating the cardiogenic TF Gata4

  8. GATA4 and GATA6 (show GATA6 Proteins) are essential for female fertility, whereas targeting either factor alone causes subfertility. GATA4 and GATA6 (show GATA6 Proteins) are also required for the expression of the receptors for prolactin (show PRL Proteins) and luteinizing hormone.

  9. Loss of Gata4 in Sertoli cells impairs the spermatogonial stem cell niche and causes germ cell exhaustion by attenuating chemokine (show CCL1 Proteins) signaling.

  10. data support the concept that under physiological conditions microbiota stimulate Gata4, which suppresses Asbt (show SLC10A2 Proteins) expression

Cow (Bovine) GATA Binding Protein 4 (GATA4) interaction partners

  1. The activity of Gata4 cardiac enhancer in transgenic embryos and in cultured aortic endothelial cells is dependent on four ETS (show ETS1 Proteins) sites.

Zebrafish GATA Binding Protein 4 (GATA4) interaction partners

  1. Study finds that emergent juvenile cortical cardiomyocytes induce expression of gata4 in a manner similar to during regeneration.

  2. ATOH8, GATA4, and FOG2 associate in a single complex

  3. gata4 gene regulates sdf1a (show CXCL12 Proteins) levels during early embryogenesis

  4. mga restricts the normal levels of Gata4 required for heart tube looping.

  5. Through the use of a transgenic reporter strain, we found that cardiomyocytes throughout the subepicardial ventricular layer trigger expression of the embryonic cardiogenesis gene gata4 within a week of trauma

  6. Gata4 and Gata6 (show GATA6 Proteins) have distinct non-redundant functions in cardiac morphogenesis, but are redundant for an early step of liver development; and Gata4 and Gata6 (show GATA6 Proteins) are essential and non-redundant for liver growth following initial budding

  7. Data show that GATA4 knockdown only affects cardiac marker expression in the absence of either GATA5 (show GATA6 Proteins) or GATA6 (show GATA6 Proteins), suggesting redundancy in this family during myocardial development.

  8. Results suggest that GATA4 and -6 play a key role in the regulation of ventricular myosin heavy chain gene expression in the ventricle.

GATA4 Protein Profile

Protein Summary

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

Alternative names and synonyms associated with GATA4

  • GATA binding protein 4 (LOC100230031)
  • GATA binding protein 4 (gata4)
  • GATA binding protein 4 (GATA4)
  • glutamyl-tRNA(Gln) amidotransferase subunit A (gatA4)
  • GATA-4 zinc-finger transcription factor (GATA-4)
  • gata4 transcription factor (gata4)
  • GATA4 (LOC100534420)
  • GATA binding protein 4 (Gata4)
  • GATA binding protein 4 (gata4-b)
  • GATA-binding protein 4 (gata4)
  • ASD2 protein
  • gata protein
  • Gata-4 protein
  • gata4 protein
  • MGC81427 protein
  • VSD1 protein
  • xGATA-4 protein
  • xgata4 protein

Protein level used designations for GATA Binding Protein 4 Proteins (GATA4)

GATA binding protein 4 , glutamyl-tRNA(Gln) amidotransferase subunit A , GATA-4 zinc-finger transcription factor , gata4 transcription factor , GATA4 , GATA-4 transcription factor , GATA-binding factor 4 , transcription factor GATA-4 , GATA-binding protein 4 , DNA-binding protein GATA-GT2 , transcription factor GATA4 , transcription factor xGATA-4 , xGATA-4

100230031 Taeniopygia guttata
443781 Xenopus laevis
472698 Pan troglodytes
549703 Xenopus (Silurana) tropicalis
696775 Macaca mulatta
5809170 Sorangium cellulosum So ce56
100008858 Oryctolagus cuniculus
100329087 Saccoglossus kowalevskii
100534420 Oreochromis niloticus
100602105 Nomascus leucogenys
396392 Gallus gallus
2626 Homo sapiens
486079 Canis lupus familiaris
397555 Sus scrofa
14463 Mus musculus
54254 Rattus norvegicus
327716 Bos taurus
100716226 Cavia porcellus
100820749 Ovis aries
399302 Xenopus laevis
30483 Danio rerio
Selected quality suppliers for GATA4 Proteins (GATA4)
Did you look for something else?