Browse our AKT2 (AKT2) ELISA Kits

Full name:
V-Akt Murine Thymoma Viral Oncogene Homolog 2 ELISA Kits (AKT2)
On www.antibodies-online.com are 19 V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) ELISA Kits from 9 different suppliers available. Additionally we are shipping AKT2 Antibodies (440) and AKT2 Proteins (24) and many more products for this protein. A total of 499 AKT2 products are currently listed.
Synonyms:
2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, PKBB, PKBBETA, pkbss, PRKBB, RAC-BETA, v-akt2

AKT2 (AKT2) ELISA Kits by Reactivity

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More ELISA Kits for AKT2 Interaction Partners

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. This review summarises and discusses the consequences of genetic deletions of Akt (show AKT1 ELISA Kits) isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 (show AKT1 ELISA Kits) and Akt2 rapidly induced mortality, hepatic Akt (show AKT1 ELISA Kits) inhibition induced liver injury that promotes hepatocellular carcinoma.

  2. Rac1 activation is caused by membrane translocation of a guanine nucleotide exchange factor (show ARHGEF12 ELISA Kits) FLJ00068 in Akt2-mediated insulin (show INS ELISA Kits) signaling in mouse skeletal muscle.

  3. BAY 1125976 is a potent and highly selective allosteric AKT1 (show AKT1 ELISA Kits)/2 inhibitor.

  4. AKT2 inhibition induces a unique mitochondrial-dependent DNA degradation pathway by activating nucleus translocation of AIF (show AIFM1 ELISA Kits) and EndoG (show ENDOG ELISA Kits) during cardiac ischemia.

  5. Akt2 ablation may protect against paraquat toxicity-induced cardiac contractile defect and apoptosis possibly via regulation of Nrf2 (show NFE2L2 ELISA Kits) activation and mitochondrial homeostasis.

  6. Loss of Akt2 enhanced lung tumor development.

  7. Akt2(-/-) mice survive hepatic Akt1 (show AKT1 ELISA Kits) deletion but all develop spontaneous hepatocellular carcinoma. They are insulin (show INS ELISA Kits) resistant. Akt2(-/-) mice are not resistant to diethylnitrosamine hepatocarcinogenesis. They have a high incidence of lung metastasis.

  8. rescued the hepatic regenerative capability in Akt1 (show AKT1 ELISA Kits)-deficient and Akt2-deficient mice

  9. Sustained endothelial Akt1/2 (show JAG1 ELISA Kits) signalling is critical in main (show NOTCH1 ELISA Kits)taining vascular stability and homeostasis, thereby preserving tissue and organ function.

  10. Akt2 upregulates dendritic cell migration at least in part by ETS1 (show ETS1 ELISA Kits)-dependent stimulation of IP3R2 (show ITPR2 ELISA Kits) transcription.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. AKT2 can regulate miR (show MLXIP ELISA Kits)-200a in a histology- or stage-specific manner and this regulation is independent of subsequent involvement of miR (show MLXIP ELISA Kits)-200a in epithelial-mesenchymal transition.

  2. This review summarises and discusses the consequences of genetic deletions of Akt (show AKT1 ELISA Kits) isoforms in adult mice and their implications for cancer therapy. Whereas combined Akt1 (show AKT1 ELISA Kits) and Akt2 rapidly induced mortality, hepatic Akt (show AKT1 ELISA Kits) inhibition induced liver injury that promotes hepatocellular carcinoma.

  3. Quinoline-type inhibitors bind in the Akt2 PH domain.

  4. TGF-beta (show TGFB1 ELISA Kits) signaling through Akt2 induces phosphorylation of heterogeneous nuclear ribonucleoprotein E1 (hnRNP E1 (show PCBP1 ELISA Kits)) at serine-43 (p-hnRNP E1 (show PCBP1 ELISA Kits)), driving epithelial to mesenchymal transition and metastasis.

  5. miR (show MLXIP ELISA Kits)-29b plays an important role in TGF-beta1 (show TGFB1 ELISA Kits)-mediated epithelial-mesenchymal transition in ARPE-19 cells by targeting Akt2.

  6. miR (show MLXIP ELISA Kits)-148a functions as tumor suppressor in Renal cell carcinoma by targeting AKT2.

  7. This was further verified in gene expression analyses, showing downregulation of genes involved in glucose metabolism. Additionally, both AKT1 (show AKT1 ELISA Kits) KO and AKT2 KO demonstrated an impaired fatty acid metabolism. However, genes were upregulated in the Wnt (show WNT2 ELISA Kits) and cell proliferation pathways, which could oppose this effect. AKT (show AKT1 ELISA Kits) inhibition should therefore be combined with other effectors to attain the best effect.

  8. Data indicate that proto-oncogene (show RAB1A ELISA Kits) protein c (show PROC ELISA Kits)-akt (Akt (show AKT1 ELISA Kits)) phosphorylates distinct sites than SRPK1 (show SRPK1 ELISA Kits) protein within the arginine-serine (RS) domain of Lamin B Receptor (LBR (show LBR ELISA Kits)).

  9. MiR (show MLXIP ELISA Kits)-650 could inhibit the proliferation, migration and invasion of rheumatoid arthritis synovial fibroblasts through targeted regulation of AKT2 expression.

  10. High AKT2 expression is associated with gallbladder cancer.

Zebrafish V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Study reports that Appl1 (show APPL1 ELISA Kits) regulates the activity of Akt (show AKT1 ELISA Kits) and, importantly, its downstream signaling specificity from an endosomal compartment, with profound implications for development.

  2. EDN1 plays an important role in hepatocellular carcinoma progression by activating the PI3K/AKT pathway and is regulated by miR-1.

  3. akt2 has a role in an integrative pathway directly linking glucose, Glut1 (show SLC2A1 ELISA Kits) expression, and activation of apoptosis

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) interaction partners

  1. Profilin (show PFN1 ELISA Kits)-dependent dissociation of G-actin (show ACTB ELISA Kits)-Tbeta4 complexes simultaneously liberates actin for filament assembly and facilitates Tbeta4 binding to integrin-linked kinase (ILK (show ILK ELISA Kits)) in the lamellipodia.

AKT2 Antigen Profile

Antigen Summary

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

Alternative names and synonyms associated with AKT2

  • v-akt murine thymoma viral oncogene homolog 2 (AKT2) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 2 (akt2) Elisa Kit
  • thymoma viral proto-oncogene 2 (Akt2) Elisa Kit
  • v-akt murine thymoma viral oncogene homolog 2 (Akt2) Elisa Kit
  • 2410016A19Rik Elisa Kit
  • AKT2 Elisa Kit
  • akt2-a Elisa Kit
  • AW554154 Elisa Kit
  • cb945 Elisa Kit
  • HIHGHH Elisa Kit
  • PKB Elisa Kit
  • PKBB Elisa Kit
  • PKBBETA Elisa Kit
  • pkbss Elisa Kit
  • PRKBB Elisa Kit
  • RAC-BETA Elisa Kit
  • v-akt2 Elisa Kit

Protein level used designations for AKT2

v-akt murine thymoma viral oncogene homolog 2 , RAC-beta serine/threonine-protein kinase , AKT2 kinase , RAC-beta serine/threonine-protein kinase-like , serine/threonine protein kinase , PKB beta , RAC-PK-beta , RAC-beta serine/threonine protein kinase , protein kinase Akt-2 , protein kinase B beta , protein kinase B, beta , murine thymoma viral (v-akt) homolog-2 , rac protein kinase beta , RAC protein kinase beta RAC-PK beta , murine thymoma viral (v-akt) oncogene homolog 2 , thymoma viral proto-oncogene 2 , PKB beta-A , RAC-PK-beta-A , RAC-beta serine/threonine-protein kinase A , protein kinase Akt-2-A , protein kinase B, beta-A , protein kinase B

GENE ID SPECIES
456035 Pan troglodytes
700591 Macaca mulatta
100144709 Xenopus (Silurana) tropicalis
100388080 Callithrix jacchus
100454279 Pongo abelii
100499544 Felis catus
100468763 Ailuropoda melanoleuca
11652 Mus musculus
208 Homo sapiens
25233 Rattus norvegicus
378972 Danio rerio
379783 Xenopus laevis
373973 Gallus gallus
449021 Canis lupus familiaris
100127478 Sus scrofa
534923 Bos taurus
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