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AKT2 Products

(V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Categories

This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008].

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Featured AKT2 Categories

AKT2 Antibodies

High quality antibodies with extensive validation data.

AKT2 ELISA Kits

Reliable ELISA kits for a wide range of species.

AKT2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AKT2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN513224
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (9)
Cat. No. ABIN950116
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), FACS
Validations
  • (5)
Cat. No. ABIN391023
Quantity 400 μL
Datasheet Datasheet

Recommended AKT2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971094
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971093
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960411
Quantity 96 tests
Datasheet Datasheet

Recommended AKT2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (3)
Cat. No. ABIN5624569
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
Cat. No. ABIN5569766
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125675
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our AKT2 products

Li, Kang, Yin, Li, Chen, Li, Zhang, Qiu: "Ginsenoside Rh2 inhibits human A172 glioma cell proliferation and induces cell cycle arrest status via modulating Akt signaling pathway." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 3062-3068, (2018) (PubMed).

Karaczyn, Adams, Cheng, Matluk, Verdi: "Human NUMB6 Induces Epithelial-Mesenchymal Transition and Enhances Breast Cancer Cells Migration and Invasion." in: Journal of cellular biochemistry, (2016) (PubMed).

Riquelme, Behrens, Lin, Simon, Papadimitrakopoulou, Izzo, Moran, Kalhor, Lee, Minna, Wistuba: "Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations." in: Cancer research, Vol. 76, Issue 3, pp. 675-85, (2016) (PubMed).

Lin, Chen, Liang, Tan: "Echistatin prevents posterior capsule opacification in diabetic rabbit model via integrin linked kinase signaling pathway." in: International journal of clinical and experimental pathology, Vol. 8, Issue 11, pp. 14294-304, (2016) (PubMed).

Jiang, Zhang, Kang, Wang, Zhang, Chen: "Celecoxib reverts oxaliplatin-induced neuropathic pain through inhibiting PI3K/Akt2 pathway in the mouse dorsal root ganglion." in: Experimental neurology, Vol. 275 Pt 1, pp. 11-6, (2016) (PubMed).

Sun, Zhang, Wang, Jin, Jia, Yu, Chen: "MiRNA-615-5p functions as a tumor suppressor in pancreatic ductal adenocarcinoma by targeting AKT2." in: PLoS ONE, Vol. 10, Issue 4, pp. e0119783, (2015) (PubMed).

Cui, Lin, Zuo, Zhang, Dong, Hu, Luo, Chen, Lu: "AKT2-knockdown suppressed viability with enhanced apoptosis, and attenuated chemoresistance to temozolomide of human glioblastoma cells in vitro and in vivo." in: OncoTargets and therapy, Vol. 8, pp. 1681-90, (2015) (PubMed).

Gezginci-Oktayoglu, Sacan, Bolkent, Ipci, Kabasakal, Sener, Yanardag: "Chard (Beta vulgaris L. var. cicla) extract ameliorates hyperglycemia by increasing GLUT2 through Akt2 and antioxidant defense in the liver of rats." in: Acta histochemica, Vol. 116, Issue 1, pp. 32-9, (2014) (PubMed).

Kuo, Lin, Huo, Su, Yang, Hsiao, Chiang, Chung, Wang, Chang, Chen, Chuu: "Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling." in: International journal of molecular sciences, Vol. 14, Issue 5, pp. 8801-17, (2013) (PubMed).

Lin, Lin, Hsiao, Wang, Jiang, Hsu, Jim, Chen, Kung, Chuu: "Difference in protein expression profile and chemotherapy drugs response of different progression stages of LNCaP sublines and other human prostate cancer cells." in: PLoS ONE, Vol. 8, Issue 12, pp. e82625, (2013) (PubMed).

Synonyms and alternative names related to AKT2

AKT serine/threonine kinase 2 (AKT2), v-akt murine thymoma viral oncogene homolog 2 (akt2), thymoma viral proto-oncogene 2 (Akt2), AKT serine/threonine kinase 2 (Akt2), v-akt murine thymoma viral oncogene homolog 2 L homeolog (akt2.L), 2410016A19Rik, AKT2, akt2-a, AW554154, cb945, HIHGHH, PKB, pkbb, PKBB, pkbbeta, PKBbeta, PKBBETA, pkbss, prkbb, PRKBB, rac-beta, RAC-BETA, v-akt2

Protein level used designations for AKT2

  • v-akt murine thymoma viral oncogene homolog 2
  • RAC-beta serine/threonine-protein kinase
  • AKT2 kinase
  • RAC-beta serine/threonine-protein kinase-like
  • serine/threonine protein kinase
  • PKB beta
  • RAC-PK-beta
  • RAC-beta serine/threonine protein kinase
  • protein kinase Akt-2
  • protein kinase B beta
  • protein kinase B, beta
  • murine thymoma viral (v-akt) homolog-2
  • rac protein kinase beta
  • RAC protein kinase beta RAC-PK beta
  • murine thymoma viral (v-akt) oncogene homolog 2
  • thymoma viral proto-oncogene 2
  • PKB beta-A
  • RAC-PK-beta-A
  • RAC-beta serine/threonine-protein kinase A
  • protein kinase Akt-2-A
  • protein kinase B, beta-A
  • protein kinase B
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