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Rat (Rattus) FOXO1 ELISA Kit for Sandwich ELISA - ABIN431805
Akbulut, Aktas, Akbulut: The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. in Biogerontology 2015
Show all 2 Pubmed References
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (show SIRT1 ELISA Kits) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (show FOXO3 ELISA Kits) is a key regulator of ROS (show ROS1 ELISA Kits)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (show NCAM1 ELISA Kits)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (show TNF ELISA Kits) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
These data suggest that high doses of insulin (show INS ELISA Kits) downregulate apoA-I (show APOA1 ELISA Kits) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (show NR1H2 ELISA Kits) complex, FOXA2 (show FOXA2 ELISA Kits), and LXRalpha (show NR1H3 ELISA Kits) on hepatic enhancer of apoA-I (show APOA1 ELISA Kits) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (show LGR5 ELISA Kits).
elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus
Results provide a mechanistic understanding for the observation that loss of IGF-1R (show IGF1R ELISA Kits) expression decreases tamoxifen sensitivity resulting from reduced FoxO1 expression in breast cancer cells.
Low FOXO1 expression is associated with invasive oral cancer.
TLR4 (show TLR4 ELISA Kits) and C5aR (show C5AR1 ELISA Kits) crosstalk in dendritic cells induces a core regulatory network of RSK2 (show RPS6KA3 ELISA Kits), PI3Kbeta, SGK1 (show SGK1 ELISA Kits), and FOXO (show FOXO3 ELISA Kits) transcription factors.
The data suggest that pre-B cells are endowed with a protective mechanism that reduces the risk for aberrant recombinations and chromosomal translocations when exposed to DNA damage, involving the ATM (show ATM ELISA Kits)-dependent regulation of FOXO1 binding to the Erag enhancer region.
expression of Bim (show BCL2L11 ELISA Kits) is mediated by FoxO1 and indirectly downregulated by thyroid hormone/thyroid hormone (show PTH ELISA Kits) receptor (show THRA ELISA Kits), leading to chemotherapy resistance and doxorubicin-promoted metastasis of hepatoma cells.
this study shows that FoxO1 plays an important role in regulating asbestos-induced apoptosis in T cells
increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene AML1 (show RUNX1 ELISA Kits)-ETO (show RUNX1T1 ELISA Kits).
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits)-FOXO1 signaling and suppressing the activation of TLR4 (show TLR4 ELISA Kits) and/or NOD2 (show NOD2 ELISA Kits) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (show MAP3K1 ELISA Kits) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (show MYLIP ELISA Kits)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (show MYLIP ELISA Kits)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (show MYH7 ELISA Kits) negatively and MyHC IIx and MyHC IIb (show MYH4 ELISA Kits) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (show TNFSF10 ELISA Kits) and Fas ligand FasL (show FASL ELISA Kits) expression during follicular atresia.
Data show that IL-4 (show IL4 ELISA Kits) induces upregulation of the junction protein claudin-5 (show CLDN5 ELISA Kits) in endothelial cells (ECs) through activation of Jak (show JAK3 ELISA Kits)/STAT6 (show STAT6 ELISA Kits) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (show CEBPB ELISA Kits) regulate preadipocyte adipogenesis possibly through C/EBPb (show CEBPB ELISA Kits)-> FoxO1-> C/EBPb (show CEBPB ELISA Kits) feedback regulatory loop and FoxO1-C/EBPb (show CEBPB ELISA Kits) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (show PI3 ELISA Kits)-kinase and Akt (show AKT1 ELISA Kits) are activated after renal ischemia/reperfusion and that Akt (show AKT1 ELISA Kits) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (show FOXO3 ELISA Kits), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
data reveal apelin (show APLN ELISA Kits) as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin (show APLN ELISA Kits)-13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Besides, both in vivo and in votro studies suggested that K145 stimulated insulin (show INS ELISA Kits) dependent Akt (show AKT1 ELISA Kits) phosphorylation and subsequently activates FoxO1 phosphorylation therefore inhibited gluconeogenetic genes expression including PEPCK (show PEPCK ELISA Kits) and G6pase (show G6PC ELISA Kits). Our study figures out a potential extent increase the value of developing K145 as therapeutic candidate for diabetes.
Ikaros (show IKZF1 ELISA Kits) is a transcriptional regulator required for maintaining levels of Foxo1 gene expression in naive T-cells.
this study shows that Foxo1 is a positive regulatory factor for the proliferation and activity of Treg cells
Data show that Fos-Related Antigen-2 (Fra-2 (show FOSL2 ELISA Kits)) is a key upstream regulator of forkhead box O1 (Foxo1) and interferon regulatory factor 4 (Irf4 (show IRF4 ELISA Kits)) expression and influences proliferation and differentiation of B cells at multiple stages.
ANG2 (show ANGPT2 ELISA Kits) activation of Tie2 (show TEK ELISA Kits) supports stable enlargement of normal nonleaky vessels, but reduction of Tie1 (show TIE1 ELISA Kits) in inflammation leads to ANG2 (show ANGPT2 ELISA Kits) antagonism of Tie2 (show TEK ELISA Kits) and initiates a positive feedback loop wherein FOXO1-driven ANG2 (show ANGPT2 ELISA Kits) expression promotes vascular remodeling and leakage
Link between the antioxidative activity of FoxO1 with PINK1/Parkin (show PARK2 ELISA Kits)-induced mitophagy, indicating a novel role of FoxO1 in diabetic nephropathy.
Pyruvate dehydrogenase kinase 4 (show PDK4 ELISA Kits) is a direct transcriptional target of FoxO1 in the heart. FoxO1 directly regulates Pdk4 (show PDK4 ELISA Kits) transcription in the heart, thereby controlling PDH (show PDP ELISA Kits) activity and subsequent glucose oxidation rates.
the overlap of IR and IGF1R (show IGF1R ELISA Kits) signaling is critical to the regulation of muscle protein turnover, and this regulation depends on suppression of FoxO (show FOXO3 ELISA Kits)-regulated, autophagy-mediated protein degradation
These results suggest that the LKB1 (show STK11 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (show SOD1 ELISA Kits) and catalase (show CAT ELISA Kits) mRNA and protein levels in this organ.
These results indicate that miR (show MYLIP ELISA Kits)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (show GAS6 ELISA Kits) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (show AKT1 ELISA Kits)-dependent inactivation of FOXO1a.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like