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Rat (Rattus) FOXO1 ELISA Kit for Sandwich ELISA - ABIN431805
Akbulut, Aktas, Akbulut: The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. in Biogerontology 2015
Show all 2 Pubmed References
Foxo1 signaling contributes to maintainance and exacerbation inflammation and insulin (show INS ELISA Kits) resistance in polycystic ovary syndrome macrophages.
Low FOXO1 expression is associated with hepatocellular carcinoma.
presence of a new non-consensus FoxO1 binding site on the G6PC1 (show G6PC ELISA Kits) promoter that overlaps the CRE, suggesting a mutual exclusion mechanism for FoxO1 and CREB (show CREB1 ELISA Kits) binding at the G6PC1 (show G6PC ELISA Kits) promoter
miR (show MLXIP ELISA Kits)-196a-5p specifically downregulates the expression of forkhead box protein O1 (FOXO1) by targeting its 3' untranslated region (3'-UTR (show UTS2R ELISA Kits)). FOXO1 upregulates expression of phosphotyrosine interaction domain containing 1 (PID1 (show PID1 ELISA Kits)), thereby inhibiting GSC (show GSC ELISA Kits) tumorigenicity and growth
we saw that GLP-1 (show GCG ELISA Kits) induces phosphorylation of the epidermal growth factor receptor (show EGFR ELISA Kits) and activation of Foxo1, resulting in cell growth with concomitant enzyme release. Our work uncovers GLP-1 (show GCG ELISA Kits)-induced signaling pathways in the exocrine pancreas and suggests that increases in amylase (show AMY ELISA Kits) and lipase (show LIPG ELISA Kits) levels in subjects treated with GLP-1 receptor (show GLP1R ELISA Kits) agonists reflect adaptive growth rather than early-stage pancreatitis.
These data suggest that high doses of insulin (show INS ELISA Kits) downregulate apoA-I (show APOA1 ELISA Kits) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (show NR1H2 ELISA Kits) complex, FOXA2 (show FOXA2 ELISA Kits), and LXRalpha (show NR1H3 ELISA Kits) on hepatic enhancer of apoA-I (show APOA1 ELISA Kits) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (show LGR5 ELISA Kits).
elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus
Results provide a mechanistic understanding for the observation that loss of IGF-1R (show IGF1R ELISA Kits) expression decreases tamoxifen sensitivity resulting from reduced FoxO1 expression in breast cancer cells.
Low FOXO1 expression is associated with invasive oral cancer.
These results indicate that miR (show MYLIP ELISA Kits)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (show GAS6 ELISA Kits) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (show AKT1 ELISA Kits)-dependent inactivation of FOXO1a.
L. donovani triggered AKT (show AKT1 ELISA Kits) activation to regulate GSK-3beta (show GSK3b ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits)/FOXO-1 axis.
The data suggest autocrine nitric oxide/atrial natriuretic peptide (show NPPA ELISA Kits)-induced activation of protein kinase (show CDK7 ELISA Kits) G type Ialpha/p-AKT (show AKT1 ELISA Kits)/p-FOXO1 promotes survival and proliferation in pancreatic beta-cells.
Myocardial ischemia is associated with downregulation and posttranslational modification of cardiac FoxO1. In a mouse model of postischemic heart failure, posttranslational modulation of FoxO1 alters heart function involving collagen and protein metabolism.
Cell fate and metabolic state are linked by transcriptional regulators, such as IRF4 (show IRF4 ELISA Kits) and FoxO1, with dual roles in lineage and metabolic choice. Instructing some cells to utilize nutrients for anabolism and differentiation while other cells catabolically self-digest and self-renew may enable growth and repair in metazoa.
E4-ORF1 (show MED14 ELISA Kits) activation of PI3K in adipocytes recapitulates insulin (show INS ELISA Kits) regulation of FoxO1 but not regulation of Glut4 (show SLC2A4 ELISA Kits). This uncoupling of PI3K effects occurs despite E4-ORF1 (show MED14 ELISA Kits) activating PI3K and downstream signaling to levels achieved by insulin (show INS ELISA Kits).
results suggest that FoxO1OB might be involved in the regulation of 1,25(OH)2D3 on glucose homeostasis and bone formation, and that FoxO1OB might act as a key modulator of the capacity of the skeleton regulating metabolic homeostasis. Our study also provides a new idea that a combination of systemic 1,25(OH)2D3 and local FoxO1 inhibitor may be a new approach to enhance implant osseointegration.
data reveal apelin (show APLN ELISA Kits) as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin (show APLN ELISA Kits)-13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Besides, both in vivo and in votro studies suggested that K145 stimulated insulin (show INS ELISA Kits) dependent Akt (show AKT1 ELISA Kits) phosphorylation and subsequently activates FoxO1 phosphorylation therefore inhibited gluconeogenetic genes expression including PEPCK (show PEPCK ELISA Kits) and G6pase (show G6PC ELISA Kits). Our study figures out a potential extent increase the value of developing K145 as therapeutic candidate for diabetes.
Ikaros (show IKZF1 ELISA Kits) is a transcriptional regulator required for maintaining levels of Foxo1 gene expression in naive T-cells.
this study shows that Foxo1 is a positive regulatory factor for the proliferation and activity of Treg cells
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (show AKT1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits)-FOXO1 signaling and suppressing the activation of TLR4 (show TLR4 ELISA Kits) and/or NOD2 (show NOD2 ELISA Kits) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (show MAP3K1 ELISA Kits) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (show MYLIP ELISA Kits)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (show MYLIP ELISA Kits)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (show MYH7 ELISA Kits) negatively and MyHC IIx and MyHC IIb (show MYH4 ELISA Kits) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (show TNFSF10 ELISA Kits) and Fas ligand FasL (show FASL ELISA Kits) expression during follicular atresia.
Data show that IL-4 (show IL4 ELISA Kits) induces upregulation of the junction protein claudin-5 (show CLDN5 ELISA Kits) in endothelial cells (ECs) through activation of Jak (show JAK3 ELISA Kits)/STAT6 (show STAT6 ELISA Kits) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (show CEBPB ELISA Kits) regulate preadipocyte adipogenesis possibly through C/EBPb (show CEBPB ELISA Kits)-> FoxO1-> C/EBPb (show CEBPB ELISA Kits) feedback regulatory loop and FoxO1-C/EBPb (show CEBPB ELISA Kits) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (show PI3 ELISA Kits)-kinase and Akt (show AKT1 ELISA Kits) are activated after renal ischemia/reperfusion and that Akt (show AKT1 ELISA Kits) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (show FOXO3 ELISA Kits), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (show SIRT1 ELISA Kits) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (show FOXO3 ELISA Kits) is a key regulator of ROS (show ROS1 ELISA Kits)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (show NCAM1 ELISA Kits)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (show TNF ELISA Kits) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (show SOD1 ELISA Kits) and catalase (show CAT ELISA Kits) mRNA and protein levels in this organ.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like