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Browse our MTOR (FRAP1) ELISA Kits

Full name:
Mechanistic Target of Rapamycin (serine/threonine Kinase) ELISA Kits (FRAP1)
On www.antibodies-online.com are 35 Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) ELISA Kits from 11 different suppliers available. Additionally we are shipping MTOR Antibodies (350) and MTOR Proteins (4) and many more products for this protein. A total of 403 MTOR products are currently listed.
Synonyms:
2610315D21Rik, AI327068, flat, FRAP, frap1, FRAP2, RAFT1, RAPT1, tor, wu:fc22h08
list all ELISA KIts Gene Name GeneID UniProt
FRAP1 2475 P42345
FRAP1 56717 Q9JLN9
FRAP1 56718 P42346

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More ELISA Kits for MTOR Interaction Partners

Horse (Equine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

Human Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. A slight overexpression of PIK3CA (show PIK3CA ELISA Kits), PIK3CB, AKT1 (show AKT1 ELISA Kits), MTOR, RPS6KB1 (show RPS6KB1 ELISA Kits), EIF4EBP1 (show EIF4EBP1 ELISA Kits) and EIF4E (show EIF4E ELISA Kits) genes.

  2. The biological association between mTOR activation and AR pathway suggests that there may exist a subgroup of TNBC.

  3. The proteins of the pathways p-Akt (show AKT1 ELISA Kits), p-mTOR, p-p70S6K (show RPS6KB1 ELISA Kits) and p-4E-BP1 (show EIF4EBP1 ELISA Kits) were downregulated.

  4. Tan-IIA was able to decrease the protein expression levels of EGFR (show EGFR ELISA Kits), IGFR, PI3K (show PIK3CA ELISA Kits), AKT (show AKT1 ELISA Kits) and mTOR.

  5. Phosphorylation level of Akt (show AKT1 ELISA Kits) declined from 138.45+/-13.8 to 69.9+/-29.7% in SGC (show SGCB ELISA Kits)-7901, and from 115.5+/-26.6 to 49.07+/-27% in MGC-803 and phosphorylation level of mTOR also significantly decreased.While apoptosis of gastric cancer(GA) cells increased which we verified with apoptosis proteins and staining analysis. Our data showed that RLIP76 (show RALBP1 ELISA Kits) plays a significant oncogenic role in GC and it maybe a potential target in GC

  6. Our results demonstrated that NC inhibits development of glioblastoma multiforme (GBM) by targeting the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/mTOR signaling pathway and provides a potential therapeutic agent for the treatment of GBM.

  7. The PI3K (show PIK3CA ELISA Kits)-Akt (show AKT1 ELISA Kits)-mTOR pathway coordinates the uptake and utilization of multiple nutrients.

  8. Temsirolimus could act as an mTOR inhibitor to induce autophagy in adenoid cystic carcinoma both in vitro and in vivo.

  9. Brefeldin A appears to attenuate TNF-alpha (show TNF ELISA Kits)-stimulated inflammatory mediator production in keratinocytes by suppressing the activation of the Akt (show AKT1 ELISA Kits), mTOR, and NF-kappaB (show NFKB1 ELISA Kits) pathways.

  10. RCE-4 isolated from Reineckia carnea exerted beneficially anti-cervical cancer effect on HeLa cells, mainly inhibiting PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/mTOR signaling pathway phosphorylation and NF-kappaB (show NFKB1 ELISA Kits) activation, promoting HeLa cell apoptosis.

Mouse (Murine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. Suggest the involvement of the mTOR pathway in antipsychotic-induced extrapyramidal symptoms.

  2. Data suggest that a combined inhibition of mechanistic target of rapamycin protein (mTOR) and beta-catenin (show CTNNB1 ELISA Kits) signaling transduction may be a therapeutic strategy for patients with chronic kidney.

  3. Temsirolimus could act as an mTOR inhibitor to induce autophagy in adenoid cystic carcinoma both in vitro and in vivo.

  4. The present study indicates that regulation of DEPTOR (show DEPTOR ELISA Kits)/mTOR signaling may be an important mechanism for glutamine (show GFPT1 ELISA Kits) in prevention against the development of colitis-associated colorectal cancer (CAC (show SLC25A20 ELISA Kits)): the chemopreventive effect of dietary glutamine (show GFPT1 ELISA Kits) on CAC (show SLC25A20 ELISA Kits) is, at least in part, associated with the induction of autophagy.

  5. Shengmai injection provides remarkable protection against cerebral ischemia/reperfusion injury, which may be partly due to the inhibition of autophagy via AMPK (show PRKAA1 ELISA Kits)/mTOR/JNK (show MAPK8 ELISA Kits) pathways.

  6. These results suggested that inhibition of mTOR had a neuroprotective effect on serumdeprived 661W cells. In conclusion, the mTOR pathway is a critical molecular signal for cell cycle regulation and energy metabolism, and inhibiting the mTOR pathway may attenuate neurotrophin (show BDNF ELISA Kits) withdrawalinduced damage.

  7. The down-regulation of p27 (show CDKN1B ELISA Kits) and the activation of mTOR pathway may be involved in miR (show MLXIP ELISA Kits)-222-induced heart failure and autophagy inhibition.

  8. The results suggest that KCa3.1 (show KCNN4 ELISA Kits) activation contributes to dysfunctional tubular autophagy in diabetic nephropathy through PI3K/Akt (show AKT1 ELISA Kits)/mTOR signaling pathways.

  9. Uhrf1 (show UHRF1 ELISA Kits) regulation of the Akt (show AKT1 ELISA Kits)-mTOR signaling pathway is required for invariant natural killer T cell development.

  10. The predominant AKT (show AKT1 ELISA Kits) isoform in the central nervous system, AKT3 (show AKT3 ELISA Kits), induces much more robust axon regeneration than AKT1 (show AKT1 ELISA Kits) and that activation of mTORC1 and inhibition of GSK3beta are two critical parallel pathways for AKT (show AKT1 ELISA Kits)-induced axon regeneration.

Zebrafish Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. This study reveals the dramatic rescue effects of L-leucine stimulation of mTORC1 in RBS (show ESCO2 ELISA Kits) cells and supports that normal gene expression and translation requires ESCO2 (show ESCO2 ELISA Kits) function.

  2. By inhibiting mTOR signaling via Fbxw7 (show FBXW7 ELISA Kits), the amount of myelination during development is reduced.

  3. Apc mutations activate mechanistic target of rapamycin complex 1 in mice and zebrafish

  4. In our zebrafish model, autophagy induction does not depend on inhibition of the Tor pathway or activation of Tp53 (show TP53 ELISA Kits).

  5. TOR signaling is a common pathological pathway that can be leveraged for therapeutic benefits in cardiomyopathies of different origins.

  6. in addition to regulating cell growth and proliferation, TOR signaling controls the developmental program guiding epithelial morphogenesis in the intestine

Pig (Porcine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. Data show that the amount of proteins related to mechanistic target of rapamycin (mTOR) signaling pathways decreased along crypt-villus axis (CVA).

  2. AMPK (show PRKAA1 ELISA Kits)-mTOR-autophagy signaling is altered by intrauterine growth restriction in newborn piglets.

  3. Uroguanylin (show GUCA2B ELISA Kits) modulates (Na++K+)ATPase (show ATP1A1 ELISA Kits) in a proximal tubule cells via cGMP/protein kinase (show CDK7 ELISA Kits) G, cAMP/protein kinase A, and mTOR pathways.

  4. mTOR is involved in 17beta-estradiol-induced, cultured immature boar Sertoli cell proliferation via regulating the expression of SKP2, CCND1 (show CCND1 ELISA Kits), and CCNE1 (show CCNE1 ELISA Kits).

  5. L-Glutamine enhances enterocyte growth via activation of the mTOR.

  6. Arg, Leu, and Gln act coordinately to stimulate proliferation of pTr cells through activation of the MTOR-RPS6K-RPS6 (show RPS6 ELISA Kits)-EIF4EBP1 (show EIF4EBP1 ELISA Kits) signal transduction pathway.

  7. Data indicate that the expression of MAP1LC3A (show MAP1LC3A ELISA Kits), B and autophagy-associated genes (ATG5 (show ATG5 ELISA Kits), mTOR, Beclin-1 (show BECN1 ELISA Kits)) was increased in normal pigs, while decreased in miniature pigs.

  8. Biochemical, cellular, and molecular data suggest that L-arginine (show GATM ELISA Kits) stimulates mTOR biosynthesis, mTOR signaling, and overall protein biosynthesis/turnover in placental/trophoblast and blastocyst/ectoderm cells thereby enhancing cell proliferation.

  9. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (show PRKAA1 ELISA Kits)/ERK (show MAPK1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits)/mTOR signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

  10. Findings illustrate a mechanism for the cardioprotective effects of lovastatin through inhibition of Rheb (show RHEB ELISA Kits) and mTORC1 and promotion of a differentiated vascular smooth muscle cell phenotype.

Cow (Bovine) Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) interaction partners

  1. 14-3-3gamma (show YWHAG ELISA Kits) affects mTOR protein pathway and regulates lactogenesis in dairy cow mammary epithelial cells.

  2. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2 (show JAK2 ELISA Kits)-STAT5 (show STAT5A ELISA Kits) and mTOR signaling pathways.

  3. Insulin (show INS ELISA Kits)-induced activation of phosphoinositide 3-kinase~mTOR pathway up-regulates tau protein via acceleration of protein synthesis in adrenal chromaffin cells, promoting neurite-like process outgrowth.

  4. IGF-I (show IGF1 ELISA Kits) down-regulated functional IGF-I receptor (show IGF1R ELISA Kits) via GSK-3beta inhibition and mTOR activation; constitutive activity of GSK-3beta maintained IGF-I receptor (show IGF1R ELISA Kits) level in nonstimulated cells.

  5. stimulation of mammary protein synthesis by amino acids and its enhancement by a combination of the lactogenic hormones hydrocortisone, insulin (show INS ELISA Kits), and prolactin (show PRL ELISA Kits) were associated with increased phosphorylation of the mTOR substrates

  6. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (show AKT1 ELISA Kits), mTOR, p70S6K (show RPS6KB1 ELISA Kits), and ERK1/2 (show MAPK1/3 ELISA Kits).

  7. prostaglandin F2alpha phosphorylates TSC2 (show TSC2 ELISA Kits) and activates mTOR and ribosomal protein S6 (show RPS6 ELISA Kits) kinase (show RPS6KB1 ELISA Kits) signaling in an AKT (show AKT1 ELISA Kits)-independent manner

  8. mTOR links IGF-I (show IGF1 ELISA Kits) and EGF (show EGF ELISA Kits) signaling in inhibiting the autophagy pathways.

MTOR (FRAP1) Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

Alternative names and synonyms associated with MTOR (FRAP1)

  • mechanistic target of rapamycin (serine/threonine kinase) (MTOR) Elisa Kit
  • mechanistic target of rapamycin (serine/threonine kinase) (Mtor) Elisa Kit
  • mechanistic target of rapamycin (serine/threonine kinase) (mtor) Elisa Kit
  • 2610315D21Rik Elisa Kit
  • AI327068 Elisa Kit
  • flat Elisa Kit
  • FRAP Elisa Kit
  • frap1 Elisa Kit
  • FRAP2 Elisa Kit
  • RAFT1 Elisa Kit
  • RAPT1 Elisa Kit
  • tor Elisa Kit
  • wu:fc22h08 Elisa Kit

Protein level used designations for FRAP1

FK506 binding protein 12-rapamycin associated protein 1 , FK506 binding protein 12-rapamycin associated protein 2 , FK506-binding protein 12-rapamycin complex-associated protein 1 , FKBP-rapamycin associated protein , FKBP12-rapamycin complex-associated protein 1 , mammalian target of rapamycin , rapamycin and FKBP12 target 1 , rapamycin associated protein FRAP2 , rapamycin target protein 1 , serine/threonine-protein kinase mTOR , FKBP-rapamycin associated protein (FRAP) , FKBP-rapamycin-associated protein FRAP , FKBP12-rapamycin complex-associated protein , angiopoietin-like factor CDT6 , RAPT1 , rapamycin and FKBP12 target-1 protein , target of rapamycin

GENE ID SPECIES
100051341 Equus caballus
419455 Gallus gallus
2475 Homo sapiens
56717 Mus musculus
56718 Rattus norvegicus
324254 Danio rerio
478232 Canis lupus familiaris
100127359 Sus scrofa
100139219 Bos taurus
100860902 Capra hircus
100271659 Ovis aries
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