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Browse our anti-Ribonucleotide Reductase M1 (RRM1) Antibodies

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anti-Ribonucleotide Reductase M1 Antibodies (RRM1)
On are 117 Ribonucleotide Reductase M1 (RRM1) Antibodies from 21 different suppliers available. Additionally we are shipping Ribonucleotide Reductase M1 Proteins (19) and Ribonucleotide Reductase M1 Kits (13) and many more products for this protein. A total of 153 Ribonucleotide Reductase M1 products are currently listed.
cb396, cb838, CG5371, CHUNP6866, Dmel\\CG5371, DmRNR1, l(2)k06709, r1, RIR1, RNR1, RnrM1, RntL, RR1, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XRRM1
list all antibodies Gene Name GeneID UniProt
RRM1 6240 P23921
RRM1 20133 P07742
RRM1 685579  

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Top referenced anti-Ribonucleotide Reductase M1 Antibodies

  1. Chicken Polyclonal RRM1 Primary Antibody for WB - ABIN2782438 : Inglis: Requirement of arginine for the replication of herpes virus. in The Journal of general virology 1970 (PubMed)
    Show all 4 references for ABIN2782438

  2. Human Polyclonal RRM1 Primary Antibody for WB - ABIN1881767 : Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. in Molecular human reproduction 2010 (PubMed)
    Show all 2 references for ABIN1881767

  3. Human Monoclonal RRM1 Primary Antibody for FACS, IHC (p) - ABIN1687336 : Ulker, Duman, Sahin, Gumurdulu: ERCC1 and RRM1 as a predictive parameter for non-small cell lung, ovarian or pancreas cancer treated with cisplatin and/or gemcitabine. in Contemporary oncology (Poznań, Poland) 2015 (PubMed)

More Antibodies against Ribonucleotide Reductase M1 Interaction Partners

Human Ribonucleotide Reductase M1 (RRM1) interaction partners

  1. RRM1 and ERCC1 (show ERCC1 Antibodies) expression levels did not show any relationship with overall survival.

  2. RRM1 and ERCC wild type alleles are risk-reducing factor for Coronary artery disease (CAD (show CAD Antibodies)). Also, carrying RRM1 A allele might have a protective effect for smokers.

  3. Presence of rare AA (-37C>A) and CC (-524C>T) genotypes of the RRM1 may be favorable predictive factors for chemotherapy with platinum compounds and gemcitabine in non-small cell lung cancer patients.

  4. study finds that ERCC1 (show ERCC1 Antibodies) and RRM1 are not independent prognostic factors of recurrence in stage I non-small cell lung cancer patients

  5. mRNA expression of RRM1 was closely associated with cell proliferation and varied in seven non-Hodgkin lymphoma cell lines.

  6. A significant association has been found between RRM1 rs12806698 (-269C>A) RRM1 genotype and the risk for developing non-small cell lung cancer.

  7. Results underline the relevance of microRNA-101-3p-driven regulation of RRM1 in pancreatic ductal carcinoma gemcitabine resistance.

  8. TUBB3 (show TUBB3 Antibodies), TOP2A (show TOP2A Antibodies), CYP19A1 (show CYP19A1 Antibodies) and CYP2D6 (show CYP2D6 Antibodies) gene expression, but not protein expression, was associated with patient survival.

  9. A possible predictive impact of ribonucleotide-reductase subunit-1 (RRM1) on vinorelbine efficacy in non-small cell lung cancer (NSCLC) has been previously reported.

  10. RRM1 expression was predictive and prognostic of clinical outcome in advanced UC treated with gemcitabine plus platinum combination chemotherapy

Mouse (Murine) Ribonucleotide Reductase M1 (RRM1) interaction partners

  1. This study provides an improved understanding of the molecular basis (structure and dynamics) that governs the binding of the p54(nrb)/NonO (show NONO Antibodies) RRM1 to one of its target RNAs.

  2. This work reveals that binding of RRM1 to RRM2 (show RRM2 Antibodies) is essential for mammalian cells and provides the first loss-of-function model of the ribonucleotide reductase complex for genetic studies.

  3. analysis of transgenic overexpression of ribonucleotide reductase Rrm1 and Rrm2 (show RRM2 Antibodies) improves cardiac performance

  4. silencing RRM1 expression using siRNA could potentially be an effective strategy to overcome gemcitabine resistance.

  5. Tip60 (show KAT5 Antibodies)-dependent recruitment of RNR (show REN1 Antibodies) plays an essential role in dNTP supply for DNA repair

  6. The hexamer form of murine ribonucleotide reductase (mRR) large catalytic subunit mR1 (show MR1 Antibodies)(6) predominates over the dimer form mR1 (show MR1 Antibodies)(2) in the cytoplasm of normal cells, where the great majority of mRR activity is located.

  7. overexpression of RRM1 in human and mouse lung cancer cell lines induced PTEN expression, reduced phosphorylation of focal adhesion kinase (FAK), suppressed migration, invasion, and metastasis formation, and increased survival in an animal model.

Ribonucleotide Reductase M1 (RRM1) Antigen Profile

Antigen Summary

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

Alternative names and synonyms associated with Ribonucleotide Reductase M1 (RRM1)

  • ribonucleotide reductase M1 (RRM1) antibody
  • Ribonucleoside diphosphate reductase large subunit (RnrL) antibody
  • ribonucleotide reductase M1 (rrm1) antibody
  • ribonucleotide reductase M1 (Rrm1) antibody
  • ribonucleotide reductase M1 polypeptide (rrm1) antibody
  • cb396 antibody
  • cb838 antibody
  • CG5371 antibody
  • CHUNP6866 antibody
  • Dmel\\CG5371 antibody
  • DmRNR1 antibody
  • l(2)k06709 antibody
  • r1 antibody
  • RIR1 antibody
  • RNR1 antibody
  • RnrM1 antibody
  • RntL antibody
  • RR1 antibody
  • sb:cb548 antibody
  • wu:fb39b07 antibody
  • wu:fi14b02 antibody
  • wu:fk95f07 antibody
  • XRRM1 antibody

Protein level used designations for RRM1

ribonucleoside diphosphate reductase large subunit , CG5371-PA , RnrL-PA , ribonucleoside diphosphate reductase M1 subunit , ribonucleoside-diphosphate reductase large subunit , ribonucleoside-diphosphate reductase M1 chain , ribonucleotide reductase M1 polypeptide , ribonucleotide reductase M1 , ribonucleoside-diphosphate reductase large subunit-like , ribonucleoside-diphosphate reductase subunit M1 , ribonucleotide reductase, R1 subunit , ribonucleotide reductase large subunit , ribonucleotide reductase protein r1 class I

100053126 Equus caballus
34392 Drosophila melanogaster
450974 Pan troglodytes
717990 Macaca mulatta
100472317 Ailuropoda melanoleuca
100562780 Anolis carolinensis
100599741 Nomascus leucogenys
399431 Xenopus laevis
419081 Gallus gallus
6240 Homo sapiens
476823 Canis lupus familiaris
505537 Bos taurus
20133 Mus musculus
685579 Rattus norvegicus
100525117 Sus scrofa
100172956 Pongo abelii
30740 Danio rerio
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