Browse our Dopamine d2 Receptor Proteins (DRD2)

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Dopamine Receptor D2 Proteins (DRD2)
On are 9 Dopamine Receptor D2 (DRD2) Proteins from 5 different suppliers available. Additionally we are shipping Dopamine d2 Receptor Antibodies (109) and Dopamine d2 Receptor Kits (46) and many more products for this protein. A total of 169 Dopamine d2 Receptor products are currently listed.
CG7569, CG18741, D2, D2DR, d2r, d2r1, d2r2, DAMB, Dar2, DDR2, Dmel\\CG18741, DopD1, DOPR2, DopR99B, DopRII, Drd-2, DRD2, drd2-B, drd2b
list all proteins Gene Name GeneID UniProt
DRD2 1813 P14416
DRD2 24318 P61169
DRD2 13489 P61168

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Dopamine d2 Receptor Proteins (DRD2) by Origin

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More Proteins for Dopamine d2 Receptor Interaction Partners

Fruit Fly (Drosophila melanogaster) Dopamine Receptor D2 (DRD2) interaction partners

  1. Results suggest that the activation state of DAMB protein contributes to oxidative stress susceptibility in Drosophila and lead to a proposed model for paraquat neurotoxicity.

Rhesus Monkey Dopamine Receptor D2 (DRD2) interaction partners

  1. Mapped associations occur between changes in D2 and D3 dopamine receptor (show DRD3 Proteins) occupancy and brain hemodynamics

  2. These data provide evidence for a predisposition to self-administer cocaine based on dopamine D2 receptor availability, and demonstrate that the brain dopamine system responds rapidly following cocaine exposure.

Horse (Equine) Dopamine Receptor D2 (DRD2) interaction partners

  1. The amount of dopamine d1 receptor (show DRD1 Proteins), dopamine D2 receptor, and follicle stimulating hormone receptor (show FSHR Proteins) mRNA were quantified in ovarian tissues in anestrous and mares expressing estrus during the breeding season are reported.

Pig (Porcine) Dopamine Receptor D2 (DRD2) interaction partners

  1. The pig DRD2 gene was cloned, investigated its distribution in tissues and polymorphisms were identified.

  2. The increase in NOS protein seen in both the endothelium and vascular smooth muscle in response to cerebral vasospasm is enhanced by dopamine in a D(2)R-dependent mechanism.

Human Dopamine Receptor D2 (DRD2) interaction partners

  1. We did not find an association between dopamine D2 receptor rs1800497 polymorphism and eating behavior in Chilean children.

  2. Individual differences in task performance during distractions revealed an epistatic interaction of 2 SNPs (COMTMet108/158Val and ANKK1/DRD2TaqIA) in regulating the prefrontostriatal DA system on stimulus-driven attention capture via an electrophysiological mechanism of phase-resetting of gamma neural oscillation to the novel, distracting events.

  3. The DRD2 gene is involved in attention while the COMT (show COMT Proteins) gene is implicated in executive functions in patients with schizophrenia.

  4. Here, using PET with [(11)C]raclopride, we identified in the AKT1 (show AKT1 Proteins) gene a new variable number tandem repeat (VNTR) marker associated with baseline striatal dopamine D2/D3 receptor (show DRD3 Proteins) availability and with methylphenidate-induced striatal dopamine increases in healthy volunteers.

  5. Data indicate the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at dopamine D2 and dopamine D3 receptor (show DRD3 Proteins) subtypes, which are important therapeutic targets for the treatment of psychotic disorders.

  6. Female smokers with schizophrenia who were GG homozygous of the DRD2 receptor smoked more than the *A male smokers with schizophrenia. In bipolar patients, there were no DRD2 Taq1A genotype differences in smoking status.

  7. The migration/invasiveness of pituitary tumors is promoted by the activation of cofilin (show CFL1 Proteins), which can be regulated by DRD2/ROCK.

  8. An uncorrected exploratory analysis revealed associations between GABBR2 (show GABBR2 Proteins), GABRA2 (show GABRA2 Proteins) and DRD2 variants with transcranial magnetic stimulation measures of corticospinal excitability and cortical inhibition in Huntington's disease, as well as with age at onset.

  9. Results revealed that the DRD2 genotype modulates the impact of music as opposed to noise on mood states and emotion-related prefrontal and striatal brain activity, evidencing a differential susceptibility for the affect-modulatory effects of music and noise on the GG and GT genotypes, identify a biological source of variability in the impact of sound environments on emotional responses

  10. Greater sensation-seeking was observed among individuals who possessed DRD2 genotypes that code for reduced dopaminergic functioning, and this heightened sensation-seeking predicted higher levels of aggression.

Mouse (Murine) Dopamine Receptor D2 (DRD2) interaction partners

  1. MIce that selectively lack dopamine type 2 receptors (D2Rs) from pituitary lactotropes have chronic high prolactin (show PRL Proteins) levels associated with increased body weight, marked increments in fat depots, adipocyte size, and serum lipids, and a metabolic phenotype.

  2. Data show that the fine control of excitatory transmission by glycogen synthase kinase 3 (show GSK3a Proteins) requires recruitment of dopamine D2-receptors and depends on the presence of serotonin 5-HT1A (show HTR1A Proteins)-receptors.

  3. Study found no differences in the D2R binding following ten-day methamphetamine administration and seven-day withdrawal, possibly suggesting that alterations in the D2R are not involved in the emergence of anxiety-related symptoms and the development of psychomotor sensitization during withdrawal

  4. Results suggest that the role of reduced D2 receptor in obesity lies not in increasing appetitive motivation and generating compulsive eating but rather in altering activity and energy expenditure, favoring reduced behavioral expenditure of energy. More broadly, these data are consistent with a fundamental role for dopamine in regulating behavioral energy expenditure.

  5. D2R agonist treatment blocks tumor growth, induces regression of the aberrant blood supply and normalizes blood vessels. An anti-Vegf therapy is also effective to restrain tumor growth and improves vascular remodeling. Importantly, only the combination treatment suppresses intratumoral hemorrhage and restores blood vessel perfusion, suggesting that it might represent an attractive therapy targeting tumor vasculature

  6. Data indicate a contribution of D2 dopamine receptors to the effects of repetitive transcranial magnetic stimulation (rTMS) on postsynaptic density protein-95 (PSD-95 (show DLG4 Proteins)) and cyclin-dependent kinase 5 (CDK5 (show CDK5 Proteins)) levels.

  7. These results suggest that DRD2 activation is involved in alleviation of CIA (show NCOA5 Proteins) symptoms by amelioration of Th17/Treg imbalance.

  8. Study demonstrated that chronic social defeat stress induced increased expression of DRD2 dimers in the prefrontal cortex of susceptible and/or unsusceptible mice

  9. Through a combination of pharmacological and genetic tools, study provides convergent evidence of D2 (rather than D1) pathway dominant effects of PDE10A (show PDE10A Proteins) inhibition in rodents

  10. reveal differential roles of dopamine D1 receptor (show DRD1 Proteins) - and dopamine D2 receptor -containing accumbal shell neurons in the development of behavioral sensitization to psychostimulants

Cow (Bovine) Dopamine Receptor D2 (DRD2) interaction partners

  1. Studied a novel Dopamine Receptor 2 (DRD2) G/A SNP for resistance to fescue toxicosis.

Guinea Pig Dopamine Receptor D2 (DRD2) interaction partners

  1. Dopamine D2 receptor play role in memory consolidation.

Dopamine d2 Receptor (DRD2) Protein Profile

Protein Summary

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia\; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

Alternative names and synonyms associated with Dopamine d2 Receptor (DRD2)

  • Dopamine receptor 2 (DopR2)
  • dopamine receptor D2 (DRD2)
  • dopamine receptor D2 like (drd2l)
  • dopamine D2 receptor 1 (d2r1)
  • dopamine D2 receptor 2 (d2r2)
  • dopamine receptor D2 (drd2-a)
  • dopamine receptor D2 (drd2-B)
  • dopamine receptor D2 (LOC100534521)
  • dopamine receptor D2 (Drd2)
  • CG7569 protein
  • CG18741 protein
  • D2 protein
  • D2DR protein
  • d2r protein
  • d2r1 protein
  • d2r2 protein
  • DAMB protein
  • Dar2 protein
  • DDR2 protein
  • Dmel\\CG18741 protein
  • DopD1 protein
  • DOPR2 protein
  • DopR99B protein
  • DopRII protein
  • Drd-2 protein
  • DRD2 protein
  • drd2-B protein
  • drd2b protein

Protein level used designations for Dopamine Receptor D2 Proteins (DRD2)

CG18741-PA , CG18741-PB , CG18741-PC , D[[2]]-like receptor , DopR2-PA , DopR2-PB , DopR2-PC , dopamine receptor 2 , dopamine receptor in mushroom bodies , dopamine-2 receptor , D(2) dopamine receptor , D2 dopamine receptor , Dopamine D2 receptor , dopamine receptor D2b , dopamine D2 receptor 1 , dopamine D2 receptor 2 , D(2) dopamine receptor A , D2R 1 , D2R-A , dopamine receptor D2 , dopamine D2 receptor , dopamine receptor D2 isoform , seven transmembrane helix receptor , D2 receptor , dopamine receptor 2 protein

43484 Drosophila melanogaster
100303660 Meleagris gallopavo
378718 Danio rerio
100136061 Oncorhynchus mykiss
100136062 Oncorhynchus mykiss
378584 Xenopus laevis
378597 Xenopus laevis
694181 Macaca mulatta
100062195 Equus caballus
100191007 Taeniopygia guttata
100519164 Sus scrofa
100534521 Oreochromis niloticus
1813 Homo sapiens
24318 Rattus norvegicus
13489 Mus musculus
403701 Canis lupus familiaris
281126 Bos taurus
100347371 Oryctolagus cuniculus
100732584 Cavia porcellus
100624857 Sus scrofa
428252 Gallus gallus
101113525 Ovis aries
451553 Pan troglodytes
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