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Doublecortin Proteins

(Doublecortin (DCX))

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].

recommended

Doublecortin Protein (DCX) (AA 1-360) (GST tag) (ABIN1351244)

DCX Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

Doublecortin Protein (DCX) (AA 107-208) (His-IF2DI Tag) (ABIN7122702)

DCX Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA

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recommended

Doublecortin Protein (DCX) (AA 1-365) (Strep Tag) (ABIN3078822)

Crystallography grade DCX Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA

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Doublecortin Proteins by Grade

Find Doublecortin Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Doublecortin Proteins by Origin

Find Doublecortin Proteins for a variety of species such as anti-Human Doublecortin, anti-Rat Doublecortin, anti-Mouse Doublecortin. The species listed below are among those available. Click on a link to go to the corresponding products.

Doublecortin Proteins by Source

Here you will find Doublecortin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Doublecortin Proteins by Protein Type

Here you can find Doublecortin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Doublecortin Proteins by Application

Find Doublecortin Proteins validated for a specific application such as WB, SDS, ELISA, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Doublecortin Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Doublecortin Protein (DCX) (AA 1-360) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1351244

Quantity 10 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 107-208) (His-IF2DI Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7122702

Quantity 50 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 1-365) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3078822

Quantity 1 mg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 1-366) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3132219

Quantity 1 mg

Datasheet Datasheet

Doublecortin Protein (DCX) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7317238

Quantity 50 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (His tag)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396373

Quantity 100 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396367

Quantity 100 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 1-366) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7396370

Quantity 100 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 1-361, full length) (His tag)

Reactivity Chicken

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN1095575

Quantity 100 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2712278

Quantity 20 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719681

Quantity 20 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719682

Quantity 20 μg

Datasheet Datasheet

Doublecortin Protein (DCX) (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2719683

Quantity 20 μg

Datasheet Datasheet

Doublecortin Protein (DCX)

Reactivity Rat

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN6379085

Quantity 1 mg

Datasheet Datasheet

Doublecortin Protein (DCX) (AA 1-365) (His tag)

Reactivity Rat

Source Yeast

Validations

Cat. No. ABIN1656893

Quantity 1 mg

Datasheet Datasheet

Latest Publications for our Doublecortin Proteins

Jiang, Brackeva, Stangé, Verhaeghen, Costa, Couillard-Després, Rotheneichner, Aigner, Van Schravendijk, Pipeleers, Ling, Gorus, Martens: "LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro." in: Journal of proteomics, Vol. 80, pp. 268-80, (2013) (PubMed).

Aliases for Doublecortin Proteins

doublecortin (DCX) Proteins
doublecortin (Dcx) Proteins
18C15.5 Proteins
DBCN Proteins
Dbct Proteins
DC Proteins
DCX Proteins
LISX Proteins
SCLH Proteins
XLIS Proteins

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Doublecortin Proteins by Grade

Doublecortin Proteins by Origin

Doublecortin Proteins by Source

Doublecortin Proteins by Protein Type

Doublecortin Proteins by Application

Popular Doublecortin Proteins

Latest Publications for our Doublecortin Proteins

Aliases for Doublecortin Proteins

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