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Browse our anti-Ghrelin/obestatin Prepropeptide (GHRL) Antibodies

Full name:
anti-Ghrelin/obestatin Prepropeptide Antibodies (GHRL)
On www.antibodies-online.com are 260 Ghrelin/obestatin Prepropeptide (GHRL) Antibodies from 23 different suppliers available. Additionally we are shipping Ghrelin/obestatin Prepropeptide Kits (96) and Ghrelin/obestatin Prepropeptide Proteins (17) and many more products for this protein. A total of 443 Ghrelin/obestatin Prepropeptide products are currently listed.
Synonyms:
2210006E23Rik, Gh1-1, GHR, GRHL, m46, MTLRP, MTLRP-AP, MTLRPAP

Most Popular Reactivities for anti-Ghrelin/obestatin Prepropeptide (GHRL) Antibodies

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Top referenced anti-Ghrelin/obestatin Prepropeptide Antibodies

  1. Human Monoclonal GHRL Primary Antibody for WB - ABIN395595 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395595

  2. Human Polyclonal GHRL Primary Antibody for IHC, ELISA - ABIN185450 : Ghigo, Broglio, Arvat, Maccario, Papotti, Muccioli: Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor. in Clinical endocrinology 2005 (PubMed)
    Show all 2 references for ABIN185450

  3. Human Polyclonal GHRL Primary Antibody for IF (p), IHC (p) - ABIN668991 : Lemarié, Beauchamp, Dayot, Duby, Legrand, Rioux: Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. in PLoS ONE 2015 (PubMed)
    Show all 2 references for ABIN668991

  4. Human Monoclonal GHRL Primary Antibody for IHC (p), ELISA - ABIN565666 : Goitein, Lederfein, Tzioni, Berkenstadt, Venturero, Rubin: Mapping of ghrelin gene expression and cell distribution in the stomach of morbidly obese patients--a possible guide for efficient sleeve gastrectomy construction. in Obesity surgery 2012 (PubMed)

More Antibodies against Ghrelin/obestatin Prepropeptide Interaction Partners

Mouse (Murine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. des (show DES Antibodies)-acyl ghrelin produces an anxiogenic effect under nonstressed conditions, but this switches to an anxiolytic effect under stress

  2. data support the notion that ghrelin activates ParaVentricular Nucleus CRF (show CRH Antibodies) neurons via inhibition of local GABAergic tone, in an Arcuate nucleus-independent manner.

  3. ghrelin may mediate part of its metabolic actions through modulation of hypothalamic astrocytes and that this effect could involve astrocyte mediated changes in local glucose and glutamate (show GRIN1 Antibodies) metabolism that alter the signals/nutrients reaching neighboring neurons.

  4. These studies reemphasize the beneficial effects imparted by co-administration of obestatin and CCK8 (show CCK Antibodies) and their potential use towards countering obesity.

  5. Stress in a postpartum mother has persistent effects on the body weight of their offspring. Increased ghrelin and decreased leptin (show LEP Antibodies) expression in the stomach may play a role in these effects.

  6. Data (including data from studies in cell line from knockout mice) suggest high incorporation of long-chain fatty acids, partly mediated by Acsl1 (show Acsl1 Antibodies), plays role in supply of octanoic acid for ghrelin acylation/lipoylation in ghrelin-producing cells.

  7. Data show that chronic caloric restriction (CR) alters hypothalamic agouti-related protein (Agrp (show AGRP Antibodies)) and neuropeptide Y (Npy (show NPY Antibodies)) gene expression similarly in Ghrelin+/+, Ghrelin-/-, ghrelin receptor Ghsr (show GHSR Antibodies)+/+, and Ghsr (show GHSR Antibodies)-/- mice.

  8. The expression of ghrelin and GH secretagogue receptor 1a [GHSR1a] in cerebral arteries and the effects of ghrelin analogs on cerebrovascular function are reproted.[GHSR1a]

  9. Pax6 (show PAX6 Antibodies) inactivation in the adult pancreas reveals ghrelin as endocrine cell maturation marker.

  10. Thus, GHSR1a differentially inhibits CaV2 (show CAV2 Antibodies) channels by Gi/o or Gq protein pathways depending on its mode of activation.

Rabbit Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Study suggests that ghrelin promotes the growth and osteogenic differentiation of rBMSC primarily through the ERK1/2 (show MAPK1/3 Antibodies) pathway.

Rainbow Trout (Oncorhynchus mykiss) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. Data show that ghrelin was identified in cultured differentiated adipocytes, but did not influence either preadipocyte proliferation or differentiation, indicating that it may have other adipose-related roles.

  2. data provides evidence for the first time in fish of a possible modulatory role of ghrelin on the metabolic regulation by fatty acid of food intake occurring in the hypothalamus

Human Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. In hemodialysis patients, plasma ghrelin level was associated with the endoscopic and serological severity of atrophy related to H. pylori infection.

  2. studies indicate that pharmacological targeting of the endogenous ghrelin system is a valuable approach to treat metabolic complications.

  3. Patients with intestinal metaplasia, a known precursor of gastric cancer, had significantly less plasma ghrelin levels and ghrelin/obestatin (G/O) ratio than those without intestinal metaplasia.

  4. The mechanism may be that ghrelin up-regulates the expression of cyclin D1 (show CCND1 Antibodies) via regulating Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway, which has an intimate relationship with lung diseases. These results suggested the possible role of ghrelin in treating diabetic lung diseases, especially in view of its low toxicity in humans.

  5. These results demonstrate that ghrelin lightens LPS (show IRF6 Antibodies)-induced apoptosis of human alveolar epithelial cells partly through activating the PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) pathway and thereby might benefit alleviating septic ALI.

  6. Ghrelin expression was associated with better breast cancer specific survival in univariate analyses (OR 0.55, 95% CI 0.36-0.84) and in multivariate models, adjusted for endocrine treatment and age (OR 0.57, 95% CI 0.36-0.89). Obestatin expression was non-informative (OR 1.2, 95% CI 0.60-2.46).

  7. Mothers with gestational diabetes (GD) and type 2 diabetes mellitus (T2DM) had significantly lower ghrelin levels. compared to the healthy mothers.

  8. Data suggest that a 20 km run significantly decreases plasma acylated ghrelin concentrations and energy intake during a subsequent buffet meal among well-trained long distance runners; this study on appetite regulation was conducted on male long-distance runners in Japan.

  9. analysis of the relationship between skinfold thickness and serum leptin (show LEP Antibodies), ghrelin, adiponectin (show ADIPOQ Antibodies), and resistin (show RETN Antibodies) levels in infants of diabetic mothers

  10. Data suggest that high-salt intake significantly increases fasting ghrelin levels; it has been hypothesized that by up-regulating fasting ghrelin in healthy subjects, a high-salt diet may up-regulate appetite causing hyperphagia which would then lead to overweight/obesity.

Cow (Bovine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. GHRL is an important candidate gene that may be used to identify genetic variations that influence traits of economic importance in beef cattle

  2. Single nucleotide polymorphisms identified in the promoter region of the ghrelin gene could cause changes in the putative transcription factor (show TCF19 Antibodies) binding sites.

  3. The effects of dietary energy on the metabolism of ghrelin, leptin (show LEP Antibodies) and growth hormone secretagogue receptor (show GHSR Antibodies) in blood and tissues of steers are reported.

  4. ghrelin declined after glucose infusion and before the insulin (show INS Antibodies) peak; post-nadir surge in ghrelin may be regulated by the decline in circulating concentrations of glucose and nonesterified fatty acids

Goat Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. present findings suggest that ghrelin may play an important role in regulation of mammary function in lactating dairy goats via GHSR (show GHSR Antibodies)-1a

Pig (Porcine) Ghrelin/obestatin Prepropeptide (GHRL) interaction partners

  1. These expression data may indicate that factors other than ghrelin and leptin (show LEP Antibodies) are more involved in the regulation of feed intake in pigs apparently acclimated to heat stress.

  2. slc30A8 (show SLC30A8 Antibodies) colocalizes with ghrelin and motilin (show MLN Antibodies) in the gastrointestinal tract of pigs

  3. Studied an alternative vascular approach to the modulation of gastric ghrelin levels..

  4. Obestatin enhances proliferation and differentiation of preadipocytes promoting PPARgamma (show PPARG Antibodies) and C/EBPa (show CEBPA Antibodies) expression, and inhibiting preadipocyte apoptosis by decreasing expression of Caspase-3 (show CASP3 Antibodies), Caspase-7 (show CASP7 Antibodies) and Caspase-9 (show CASP9 Antibodies).

  5. The expression of ghrelin in the digestive tract of low birth weight and normal weight piglets is reported.

  6. Data suggest that a dietary factor (here, high levels of dietary copper) is able to up-regulate expression of ghrelin in the fundic gland of growing pigs; the diets tested in this study also increase feed intake and promote weight gain.

  7. Ghrelin immunolocalization in the gastrointestinal tract of pigs at different ages were studied and it was concluded that gastric ghrelin expression is not related merely to age but could also potentially be influenced by food intake.

  8. BsrI polymorphism at the ghrelin gene locus is potentially associated with carcass and meat quality traits.

  9. Plasma concentrations of ghrelin were greater before feeding and decreased after feeding in pigs fed once per day; there was no consistent pattern to ghrelin secretion in the ad libitum fed group.

  10. glucose output by primary porcine hepatocytes in suspension culture, after incubation with acylated ghrelin (AG), unacylated ghrelin (UAG), and hexarelin (HEX).

Ghrelin/obestatin Prepropeptide (GHRL) Antigen Profile

Antigen Summary

This gene encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Obestatin was initially reported to be an endogenous ligand for the orphan G protein-coupled receptor GPR39 and was involved in satiety and decreased food intake\; however, these findings are controversial. Recent reports show that obestatin is involved in inhibiting thirst and anxiety, improving memory, regulating sleep, affecting cell proliferation, and increasing the secretion of pancreatic juice enzymes. Alternative promoters and alternative splicing result in multiple transcript variants, some of which encode different protein isoforms and some of which do not encode a protein but may regulate the ghrelin-obestatin preproprotein expression. In addition, antisense transcripts for this gene have been identified and may also function in regulation of the ghrelin-obestatin preproprotein expression.

Alternative names and synonyms associated with Ghrelin/obestatin Prepropeptide (GHRL)

  • ghrelin (Ghrl) antibody
  • ghrelin-like (LOC100349547) antibody
  • ghrelin/obestatin preprohormone (ghrl) antibody
  • ghrelin/obestatin prepropeptide (GHRL) antibody
  • ghrelin/obestatin prepropeptide (Ghrl) antibody
  • 2210006E23Rik antibody
  • Gh1-1 antibody
  • GHR antibody
  • GRHL antibody
  • m46 antibody
  • MTLRP antibody
  • MTLRP-AP antibody
  • MTLRPAP antibody

Protein level used designations for GHRL

appetite-regulating hormone , growth hormone secretagogue , growth hormone-releasing peptide , motilin-related peptide , preproghrelin , proghrelin , ghrelin , ghrelin, growth hormone secretagogue receptor ligand , ghrelin/obestatin preprohormone , prepro-appetite regulatory hormone , Appetite-regulating hormone , Growth hormone secretagogue , Growth hormone-releasing peptide , prepro-ghrelin , GH releasing peptide , motilin related peptide , growth hormone receptor

GENE ID SPECIES
58991 Mus musculus
100349547 Oryctolagus cuniculus
100136596 Oncorhynchus mykiss
51738 Homo sapiens
59301 Rattus norvegicus
281192 Bos taurus
100861189 Capra hircus
396728 Sus scrofa
493844 Felis catus
403587 Canis lupus familiaris
442996 Ovis aries
408185 Gallus gallus
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