Browse our anti-HLA-DRB1 (HLA-DRB1) Antibodies

Full name:
anti-HLA Class II DR beta 1 Antibodies (HLA-DRB1)
On www.antibodies-online.com are 199 HLA Class II DR beta 1 (HLA-DRB1) Antibodies from 17 different suppliers available. Additionally we are shipping HLA-DRB1 Proteins (26) and HLA-DRB1 Kits (8) and many more products for this protein. A total of 238 HLA-DRB1 products are currently listed.
Synonyms:
DRB1, DRw10, HLA-DR1B, HLA-DRB, MGC108235, SS1
list all antibodies Gene Name GeneID UniProt
HLA-DRB1 3123 P01912 , P01911 , Q29974
HLA-DRB1    
HLA-DRB1    

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Top referenced anti-HLA-DRB1 Antibodies

  1. Human Monoclonal HLA-DRB1 Primary Antibody for FACS, ICFC - ABIN2665043 : Balandraud, Picard, Reviron, Landais, Toussirot, Lambert, Telle, Charpin, Wendling, Pardoux, Auger, Roudier: HLA-DRB1 genotypes and the risk of developing anti citrullinated protein antibody (ACPA) positive rheumatoid arthritis. in PLoS ONE 2013 (PubMed)
    Show all 10 references for 2665043

  2. Human Monoclonal HLA-DRB1 Primary Antibody for FACS - ABIN2662751 : Foo, Smedby, Akers, Berglund, Irwan, Jia, Li, Conde, Darabi, Bracci, Melbye, Adami, Glimelius, Khor, Hjalgrim, Padyukov, Humphreys, Enblad, Skibola, de Bakker, Liu: Coding variants at hexa-allelic amino acid 13 of HLA-DRB1 explain independent SNP associations with follicular lymphoma risk. in American journal of human genetics 2013 (PubMed)
    Show all 10 references for 2662751

  3. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN1944757 : Tonnelle, DeMars, Long: DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. in The EMBO journal 1986 (PubMed)
    Show all 5 references for 1944757

  4. Human Monoclonal HLA-DRB1 Primary Antibody for EIA, FACS - ABIN238469 : Klotz: Ligand-receptor complexes: origin and development of the concept. in The Journal of biological chemistry 2003 (PubMed)
    Show all 2 references for 238469

  5. Human Polyclonal HLA-DRB1 Primary Antibody for WB - ABIN516510 : Cao, Schmitz, Yang, Hogan, Bunch, Hu, Jennette, Berg, Arnett, Jennette, Falk, Preston: DRB1*15 allele is a risk factor for PR3-ANCA disease in African Americans. in Journal of the American Society of Nephrology : JASN 2011 (PubMed)

More Antibodies against HLA-DRB1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. this study proposes a mechanism for HLA-DRB1*1501 susceptibility for Goodpasture's disease in Chinese patients

  2. This study has demonstrated strong association of major histocompatibility complex haplotypes with increased and reduced risk of HPV-associated cervical cancers, with findings implicating both HLA Class I and Class II loci. These associations are driven by the identity of amino-acids at positions 13 and 71 in HLA-DRB1 and 156 in HLA-B.

  3. Although predominant associations with the HLA-DRB1 locus have been known for decades, recent data have revealed additional insight into the likely causative variants within HLA-DRB1 as well as within other HLA loci that contribute to disease risk. In addition, more than 100 common variants in non-HLA loci have been implicated in disease susceptibility

  4. This study revevled that The HLA-DRB1*03:01 allele was associated with neuromyelitis optica regardless the neuromyelitis optica -IgG status but did not influence the long term disability.

  5. There was an increased risk of rheumatoid arthritis among mothers who had any child with shared epitope, DERAA, or valine, lysine and alanine at DRB1 (show RBM45 Antibodies) positions 11, 71 and 74, respectively.

  6. Variation at HLA-DRB1 was associated with rheumatoid arthritis in an Arab population.

  7. HLA-DRB1*03:01, DRB1 (show RBM45 Antibodies)*01:01, and DRB1 (show RBM45 Antibodies)*13:01 were associated with risk of sporadic inclusion body myositis.

  8. Results show that hypomethylation of HLA-DRB1 is associated with HLA-DRB1 mRNA expression and severity of the disease, indicating that hypomethylation of HLA-DRB1 may play roles in the pathogenesis of psoriasis.

  9. DRB1 (show RBM45 Antibodies)*12:02 was more frequently expressed among the cases of Epoetin (show EPO Antibodies)-associated pure red cell aplasia than healthy controls

  10. HLA-DRB1 provides additional information for the selection of patients with high probability of monogenic diabetes.

HLA-DRB1 Antigen Profile

Antigen Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Alternative names and synonyms associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
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