Browse our anti-PEPCK (PEPCK) Antibodies

Full name:
anti-phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) Antibodies (PEPCK)
On are 78 phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) Antibodies from 17 different suppliers available. Additionally we are shipping PEPCK Kits (12) and PEPCK Proteins (5) and many more products for this protein. A total of 102 PEPCK products are currently listed.
1810010O14Rik, 9130022B02Rik, AI265463, id:ibd5157, pck, Pck-1, pckA, pepC, PEPCK, PEPCK-M, PEPCK2, ppc, SCE66.06c, VF2478, zgc:77867
list all antibodies Gene Name GeneID UniProt
PEPCK 18534 Q9Z2V4
PEPCK 5106 Q16822
PEPCK 361042  

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Most Popular Reactivities for anti-PEPCK (PEPCK) Antibodies

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anti-Mouse (Murine) PEPCK Antibodies:

anti-Human PEPCK Antibodies:

anti-Rat (Rattus) PEPCK Antibodies:

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Top referenced anti-PEPCK Antibodies

  1. Human Polyclonal PEPCK Primary Antibody for EIA, IHC (p) - ABIN360567 : Modaressi, Brechtel, Christ, Jungermann: Human mitochondrial phosphoenolpyruvate carboxykinase 2 gene. Structure, chromosomal localization and tissue-specific expression. in The Biochemical journal 1998 (PubMed)
    Show all 3 references for 360567

  2. Guinea Pig Polyclonal PEPCK Primary Antibody for ELISA, WB - ABIN250823 : Zhou, Li, Qi, Zhang, Zhang, Wu, Hu, Wu, Liu, Yan, Jing, Liu, Zhai: Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity. in Diabetologia 2012 (PubMed)
    Show all 2 references for 250823

  3. Human Polyclonal PEPCK Primary Antibody for ELISA, WB - ABIN185483 : Duplus, Benelli, Reis, Fouque, Velho, Forest: Expression of phosphoenolpyruvate carboxykinase gene in human adipose tissue: induction by rosiglitazone and genetic analyses of the adipocyte-specific region of the promoter in type 2 diabetes. in Biochimie 2004 (PubMed)
    Show all 2 references for 185483

  4. Miscanthus giganteus Polyclonal PEPCK Primary Antibody for WB - ABIN249350 : Aragón, Pascual, González, Escalona, Carvalho, Amancio: The physiology of ex vitro pineapple (Ananas comosus L. Merr. var MD-2) as CAM or C3 is regulated by the environmental conditions: proteomic and transcriptomic profiles. in Plant cell reports 2013 (PubMed)

More Antibodies against PEPCK Interaction Partners

Mouse (Murine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Pck1 (show PCK1 Antibodies) in liver plays role in glucose homeostasis; here, Pck1 (show PCK1 Antibodies) deficiency (in knockout mice) can be successfully treated by re-expression of Pck1 (show PCK1 Antibodies) in liver, thus partially rescuing pups from fatal neonatal hypoglycemia. Pck1 (show PCK1 Antibodies) appears to play roles in metabolism in lung and skeletal muscle.

  2. Lactate maintains/induces populations of postnatal neuronal progenitors/neural stem cells in a PEPCK-M-dependent manner

  3. Silencing PCK1 (show PCK1 Antibodies) or inhibiting its enzymatic activity slows the growth of tumor-repopulating cells in vitro and impedes tumorigenesis in vivo.

  4. Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.

  5. PEPCK-M expression partially rescued defects in lipid metabolism, gluconeogenesis and TCA cycle function impaired by PEPCK-C deletion, while approximately 10% re-expression of PEPCK-C normalized most parameters.

  6. FAT/CD36 (show CD36 Antibodies) regulates PEPCK in adipose tissue and that this could be secondary to reductions in lipolysis.

  7. PCB (show PC Antibodies) 126 blunted the forskolin-stimulated increase in phosphoenolpyruvate carboxykinase (PEPCK) mRNA levels.

  8. the role of IL-6 (show IL6 Antibodies) signalling in adipose tissue during exercise

  9. there are multiple cytokine pathways by which inflammation inhibits PEPCK expression in adipose tissue which could contribute to the increased mobilization of fatty acids during inflammation

  10. Glucagon (show GCG Antibodies) can also regulate Pck1 (show PCK1 Antibodies) in the intestine, but not in the kidneys.

Human phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

  1. ApoA-IV (show APOA4 Antibodies) colocalizes with NR4A1 (show NR4A1 Antibodies), which suppresses G6Pase (show G6PC Antibodies) and PEPCK gene expression at the transcriptional level, reducing hepatic glucose output and lowering blood glucose.

  2. Results indicate that PEPCK promotes tumor growth by increasing glucose and glutamine (show GFPT1 Antibodies) metabolism, increases anabolic metabolism and promotes mTORC1 activity.

  3. Mitochondrial PCK2 regulates metabolic adaptation and enables glucose-independent tumor growth in various neoplasms.

  4. When autophagy was blocked, the level of glucose-6-phosphatase (G6Pase (show G6PC Antibodies)) and phosphoenolpyruvate carboxykinase (PEPCK) was reduced in HepG2 cells and not in Hep3B cells.

  5. PEPCK activity was elevated threefold in lung cancer samples over normal lungs and its activation mediates an adaptive response to glucose depletion in lung cancer.

  6. Amino acid limitation and ER stress inducers, conditions that activate the amino acid response (AAR) and the unfolded protein response (UPR), stimulate PCK2 gene transcription in tumor cell lines.

  7. Expression of phosphoenolpyruvate carboxykinase linked to chemoradiation susceptibility of human colon cancer cells.

  8. expression of HCV nonstructural component NS5A in Huh7 or primary hepatocytes stimulated PEPCK gene expression and glucose output in HepG2 cells.

  9. results reveal a novel link between glucose metabolism and the DNA damage signaling pathway and suggest a possible role for PEPCK and G6P in the DNA damage response

  10. Endoplasmic reticulum stress triggers suppression of AMPK (show PRKAA1 Antibodies) while increasing C/EBPbeta (show CEBPB Antibodies) and pCREB expression which activates PEPCK gene transcription.

Cow (Bovine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

  1. Transition to lactation does not alter expression of the mitochondrial form of PEPCK.

Pig (Porcine) phosphoenolpyruvate Carboxykinase 2 (Mitochondrial) (PEPCK) interaction partners

  1. Concurrent binding and modifications of AUF1 (show HNRNPD Antibodies) and HuR (show ELAVL1 Antibodies) mediate the pH-responsive stabilization of phosphoenolpyruvate carboxykinase mRNA in kidney cells.

PEPCK Antigen Profile

Antigen Summary

This gene encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with PEPCK

  • phosphoenolpyruvate carboxykinase 2 (mitochondrial) (PCK2) antibody
  • phosphoenolpyruvate carboxykinase 2 (mitochondrial) (pck2) antibody
  • phosphoenolpyruvate carboxylase (pepc) antibody
  • phosphoenolpyruvate carboxylase (pepC) antibody
  • ppc (ppc) antibody
  • phosphoenolpyruvate carboxykinase (pck) antibody
  • phosphoenolpyruvate carboxylase (SCO3127) antibody
  • phosphoenolpyruvate carboxylase (ppc) antibody
  • PEPCase; PEPC (ppc) antibody
  • ATP (pck) antibody
  • Phosphoenolpyruvate carboxylase (Krad_3372) antibody
  • predicted phosphoenolpyruvate carboxykinase (pck) antibody
  • phosphoenolpyruvate carboxylase (Franean1_6583) antibody
  • phosphoenolpyruvate carboxykinase (LOC541622) antibody
  • phosphoenolpyruvate carboxykinase 1, cytosolic (Pck1) antibody
  • phosphoenolpyruvate carboxykinase 2 (mitochondrial) (Pck2) antibody
  • 1810010O14Rik antibody
  • 9130022B02Rik antibody
  • AI265463 antibody
  • id:ibd5157 antibody
  • pck antibody
  • Pck-1 antibody
  • pckA antibody
  • pepC antibody
  • PEPCK antibody
  • PEPCK-M antibody
  • PEPCK2 antibody
  • ppc antibody
  • SCE66.06c antibody
  • VF2478 antibody
  • zgc:77867 antibody

Protein level used designations for PEPCK

phosphoenolpyruvate carboxykinase [GTP], mitochondrial , mitochondrial phosphoenolpyruvate carboxykinase 2 , phosphoenolpyruvate carboxylase , phosphoenolpyruvate carboxykinase , Phosphoenolpyruvate carboxylase , PEP carboxykinase , PEPCK , phosphoenolpyruvate carboxykinase [ATP] , PEPCK-C , phosphoenolpyruvate carboxykinase, cytosolic , phosphoenolpyruvate carboxykinase, cytosolic [GTP] , phosphopyruvate carboxylase

100054903 Equus caballus
406473 Danio rerio
452807 Pan troglodytes
543328 Triticum aestivum
994443 Streptococcus pyogenes MGAS8232
1022839 Bifidobacterium longum NCC2705
1032110 Corynebacterium efficiens YS-314
1098561 Streptomyces coelicolor A3(2)
1108462 Nostoc sp. PCC 7120
1210703 Streptomyces avermitilis MA-4680
1731756 Synechococcus sp. WH 8102
1791970 Rhodopirellula baltica SH 1
2649924 Corynebacterium diphtheriae NCTC 13129
3130488 Haloarcula marismortui ATCC 43049
3277758 Vibrio fischeri ES114
3345234 Corynebacterium glutamicum ATCC 13032
3430655 Haemophilus influenzae 86-028NP
3432866 Corynebacterium jeikeium K411
3958242 Desulfitobacterium hafniense Y51
4086128 Pseudomonas entomophila L48
4194418 Haloquadratum walsbyi DSM 16790
4716199 Yersinia enterocolitica subsp. enterocolitica 8081
4848495 Actinobacillus pleuropneumoniae serovar 5b str. L20
5336474 Kineococcus radiotolerans SRS30216
5391795 Clostridium kluyveri DSM 555
5674898 Frankia sp. EAN1pec
6062153 Escherichia coli str. K-12 substr. DH10B
6221982 Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'
541622 Zea mays
18534 Mus musculus
5106 Homo sapiens
74551 Mus musculus
361042 Rattus norvegicus
282856 Bos taurus
480255 Canis lupus familiaris
403165 Sus scrofa
396457 Gallus gallus
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