Browse our anti-RNF168 (RNF168) Antibodies

Full name:
anti-Ring Finger Protein 168 Antibodies (RNF168)
On www.antibodies-online.com are 59 Ring Finger Protein 168 (RNF168) Antibodies from 15 different suppliers available. Additionally we are shipping RNF168 Proteins (6) and many more products for this protein. A total of 74 RNF168 products are currently listed.
Synonyms:
3110001H15Rik, hRNF168
list all antibodies Gene Name GeneID UniProt
RNF168 70238 Q80XJ2
RNF168 165918 Q8IYW5
RNF168 690043 B2RYR0

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More Antibodies against RNF168 Interaction Partners

Mouse (Murine) Ring Finger Protein 168 (RNF168) interaction partners

  1. RNF168, in complex with RAD6A (show ube2a Antibodies) or RAD6B (show UBE2B Antibodies), is activated in the DNA-damage-induced protein ubiquitination cascade.

  2. Rnf168 is important for maintaining genomic integrity, and it cooperates with p53 (show TP53 Antibodies) in suppressing tumorigenesis.

Human Ring Finger Protein 168 (RNF168) interaction partners

  1. Ubiquitin ligases RNF168, RNF169 (show RNF169 Antibodies), and RAD18 (show RAD18 Antibodies) specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 (show TP53BP1 Antibodies) chromatin recruitment may be activated by RNF168 and blocked by RNF169 (show RNF169 Antibodies) and RAD18 (show RAD18 Antibodies).

  2. deregulated RNF168/53BP1 (show TP53BP1 Antibodies) pathway could promote tumorigenesis by selecting for a more robust, better stress-adapted cancer cell phenotype, through altered DNA repair, fueling genomic instability and tumor heterogeneity

  3. Further mining of the UBE2U (show UBE2U Antibodies) interactome uncovered its cognate E3 RNF17 (show RNF17 Antibodies) as a novel factor that, via the radiosensitivity, immunodeficiency, dysmorphic features, and learning difficulties (RIDDLE) syndrome protein RNF168, enforces DNA damage responses.

  4. The association of RNF168 with PML (show PML Antibodies) NBs (show NBN Antibodies) resulted in increased ubiquitylation.

  5. Results reveal an important role of USP7 (show USP7 Antibodies) in regulating ubiquitin-dependent signaling via stabilization of RNF168.

  6. CK2 (show CSNK2A1 Antibodies)/WIP1 (show PPM1D Antibodies)-mediated modulation of LSD1 (show KDM1A Antibodies) phosphorylation facilitates RNF168-dependent ubiquitination and recruitment of 53BP1 (show TP53BP1 Antibodies) to the DNA damage sites.

  7. The ubiquitin ligase RNF168 is strictly dependent on the activity that UbK27 is required to promote chromatin ubiquitination following DNA damage.

  8. Finding that RNF8 (show RNF8 Antibodies) is less abundant than RNF168 identifies RNF8 (show RNF8 Antibodies) as a rate-limiting determinant of focal repair complex assembly

  9. Depletion of RNF8 (show RNF8 Antibodies) or RNF168 blocks the degradation of diffusely localized nuclear 53BP1 (show TP53BP1 Antibodies).

  10. The E3 ligase RNF168 promotes both H2A ubiquitylation and neddylation. RNF168 is itself a substrate for NEDD8, and neddylation of RNF168 is necessary for its E3 ubiquitin activity.

RNF168 Antigen Profile

Antigen Summary

This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome.

Alternative names and synonyms associated with RNF168

  • ring finger protein 168 (Rnf168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (rnf168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (RNF168) antibody
  • ring finger protein 168, E3 ubiquitin protein ligase (Rnf168) antibody
  • 3110001H15Rik antibody
  • hRNF168 antibody

Protein level used designations for RNF168

E3 ubiquitin-protein ligase RNF168 , ring fnger protein 168

GENE ID SPECIES
70238 Mus musculus
432198 Xenopus laevis
770166 Gallus gallus
165918 Homo sapiens
488029 Canis lupus familiaris
613812 Bos taurus
690043 Rattus norvegicus
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