Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Mouse (Murine) ZFYVE9 Antibodies:
anti-Rat (Rattus) ZFYVE9 Antibodies:
anti-Human ZFYVE9 Antibodies:
Go to our pre-filtered search.
Notch (show NOTCH1 Antibodies) binds Uninflatable, and both traffic together through Sara endosomes, which is essential to direct asymmetric endosomes motility and Notch (show NOTCH1 Antibodies)-dependent cell fate assignation.
Sara itself contributes to the control of the intestinal stem cells asymmetric division.
PP1 (show PPYR1 Antibodies) binds Sara and negatively regulates Dpp (show TGFb Antibodies) signaling in Drosophila melanogaster.
During mitosis, Sara endosomes associate with the spindle machinery to segregate into the two daughter cells, daughter cells thereby inherited equal amounts of signaling molecules and retained the Dpp (show TGFb Antibodies) signaling levels of the mother cell
asymmetric targeting of Delta and Notch (show NOTCH1 Antibodies)-containing Sara endosomes will increase Notch (show NOTCH1 Antibodies) signalling in sensory organ precursor daughter cell, pIIa, and decrease it in pIIb
This study describes the expression of two SARA (show SAR1A Antibodies) isoforms, SARA1 (show SAR1A Antibodies) and SARA2 (show SAR1B Antibodies), in mice and reports the generation and characterization of SARA (show SAR1A Antibodies) mutant mice with FYVE domain deletion. The loss of SARA (show SAR1A Antibodies) promoted skin tumor formation and malignant progression.
osteoblast targeted expression of a mutant endofin protein lacking the pp1c binding activity results in sustained signaling of the BMP type I receptor, which increases bone formation and skeletal angiogenesis.
we have identified endofin (show ZFYVE16 Antibodies) as an important signalling component required for basal and BMP-induced hepcidin (show HAMP Antibodies) expression.
SARA may serve as a potential novel target in pre-Epithelial-mesenchymal transition states for the amelioration renal fibrosis seen in chronic kidney diseases
PI3K (show PIK3CA Antibodies)-C2a was also required for TGFb (show TGFB1 Antibodies) receptor-mediated formation of SARA-Smad2 (show SMAD2 Antibodies)/3 complex
The negative influence that perturbation of RNF11 (show RNF11 Antibodies) and SARA levels exerts on the lysosomal degradation of EGFRs could underscore the significance of overexpression of RNF11 (show RNF11 Antibodies) in certain cancers.
TGF-beta1 (show TGFB1 Antibodies) can induce epithelial-to-mesenchymal transition through reduction in SARA expression, SARA is also basally regulated by its interaction with PI3K (show PIK3CA Antibodies).
no correlation between SARA expression and the levels of TGF-beta1 (show TGFB1 Antibodies)-induced phosphorylation of Smads in various B-cell lymphomas
SARA binds to ERBIN (show ERBB2IP Antibodies) using a new domain, which we have called the ERBID (ERBIN (show ERBB2IP Antibodies)-binding domain)
After stimulation with glucose, expression of SARA decreased in a time-dependent manner in epithelium to mesenchymal transition of proximal tubule cells.
Expression of a SARA mutant protein lacking the FYVE finger inhibits downstream activin A (show INHBA Antibodies) signaling in endothelial cells.
role in rab5 (show RAB5A Antibodies) mediated endocytosis
This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.
, smad anchor for receptor activation
, MAD, mothers against decapentaplegic homolog interacting protein, receptor activation anchor
, zinc finger FYVE domain-containing protein 9
, MADH-interacting protein
, novel serine protease