ZFYVE9 antibody (C-Term)

Catalog No. ABIN6266103

Product Details anti-ZFYVE9 Antibody

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFYVE9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificity: ZFYVE9 Antibody detects endogenous levels of total ZFYVE9.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZFYVE9, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ZFYVE9

Target: ZFYVE9 (Zinc Finger, FYVE Domain Containing 9 (ZFYVE9))

Alternative Name: ZFYVE9 (ZFYVE9 Products)

Synonyms: CG15667 antibody, Dmel\\CG15667 antibody, SARA antibody, dSARA antibody, sara antibody, NSP antibody, Madhip antibody, SMADIP antibody, E030027L17 antibody, MADHIP antibody, Smad anchor for receptor activation antibody, zinc finger, FYVE domain containing 9 antibody, zinc finger FYVE-type containing 9 antibody, Sara antibody, Zfyve9 antibody, ZFYVE9 antibody

Background:

Description: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Gene: ZFYVE9

Molecular Weight: 156 kDa

Gene ID: 9372

UniProt: O95405

Pathways: Protein targeting to Nucleus