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Browse our Coronin 1a Proteins (CORO1A)

Full name:
Coronin, Actin Binding Protein, 1A Proteins (CORO1A)
On www.antibodies-online.com are 10 Coronin, Actin Binding Protein, 1A (CORO1A) Proteins from 6 different suppliers available. Additionally we are shipping Coronin 1a Antibodies (93) and Coronin 1a Kits (18) and many more products for this protein. A total of 129 Coronin 1a products are currently listed.
Synonyms:
CLABP, CLIPINA, cor1a, CORO1A, fj83g12, HCORO1, Lmb3, p57, TACO, wu:fj83g12, zgc:63766
list all proteins Gene Name GeneID UniProt
CORO1A 12721 O89053
CORO1A 155151 Q91ZN1
CORO1A 11151 P31146

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Coronin 1a Proteins (CORO1A) by Origin

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More Proteins for Coronin 1a Interaction Partners

Mouse (Murine) Coronin, Actin Binding Protein, 1A (CORO1A) interaction partners

  1. the phenotype of T cell-specific Coronin 1a deletion resembles the phenotype observed with conventional (whole body) Coronin 1a knock-out mice. In summary, our findings provide formal proof of the predominant T cell-intrinsic role of Coronin 1A.

  2. phosphorylation of coronin 1 on Thr (show TRH Proteins)(418/424) by cyclin-dependent kinase (show CDK1 Proteins) (CDK) 5 (show CDK5 Proteins) activity was responsible for coronin 1-Galphas (show GNAS Proteins) association and the modulation of cAMP production

  3. Authors report that this mutation induces pleiotropic effects in Coro1A protein, including the exacerbation of Coro1A-dependent actin-binding and -bundling activities.

  4. Together, these findings both in Jurkat T cells as well as in primary T cells indicate a regulatory role of Coro1A on PKCtheta (show PRKCQ Proteins); recruitment and function downstream of the TCR leading to NF-kappaB (show NFKB1 Proteins) transactivation.

  5. An essential role for 14-3-3 zeta (show YWHAZ Proteins) in the regulation of macropinocytosis in macrophages upon cytokine stimulation through modulation of the localization of coronin 1.

  6. this work suggests that periods before and after NGF (show NGFB Proteins)-TrkA (show NTRK1 Proteins)-induced Coronin-1 expression (and likely other factors) defines two distinct axon growth states

  7. Absence of coronin 1A is associated with severe combined immunodeficiency (show PRKDC Proteins) in humans, hypomorphic mutations lead to a profound defect in naive T cells, expansion of oligoclonal memory T cells, and susceptibility to Epstein Barr B lymphoproliferation (show FAS Proteins).

  8. Our results indicate that Abp1 (show DBNL Proteins) negatively regulates BCR (show BCR Proteins) signaling by coupling actin remodeling to B (show TDO2 Proteins)-cell contraction and activation of inhibitory signaling molecules

  9. Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease.

  10. The results of this study establish Coronin-1 as an essential component of a feedback loop that mediates NGF (show NGFB Proteins)-TrkA (show NTRK1 Proteins) endosome stability, recycling and signaling as a critical mechanism governing developmental competition for survival.

Human Coronin, Actin Binding Protein, 1A (CORO1A) interaction partners

  1. Our studies demonstrate the importance of intact CORO1A C-terminal domains in thymic egress and T-cell survival, as well as in defense against viral pathogens.

  2. These findings suggest that coronin 1A modulates endothelial cell apoptosis by regulating p38beta (show MAPK11 Proteins) expression and activation.

  3. Together, these findings both in Jurkat T cells as well as in primary T cells indicate a regulatory role of Coro1A on PKCtheta (show PRKCQ Proteins); recruitment and function downstream of the TCR leading to NF-kappaB (show NFKB1 Proteins) transactivation.

  4. mutatiions result in abnormal T-cells, severe combined immunodeficiency (show PRKDC Proteins) of an epidermodysplasia verruciformis-human papilloma virus mucocutaneous syndrome with B and NK defects and shortened telomeres

  5. Nox4 (show NOX4 Proteins)-mediated redox regulation of PTP1B (show PTPN1 Proteins) serves as a modulator, in part through coronin-1C (show CORO1C Proteins), of the growth and migration of glioblastoma cells.

  6. Absence of coronin 1A is associated with severe combined immunodeficiency (show PRKDC Proteins) in humans, hypomorphic mutations lead to a profound defect in naive T cells, expansion of oligoclonal memory T cells, and susceptibility to Epstein Barr B lymphoproliferation (show FAS Proteins).

  7. Results indicate that Coronin1 proteins are at the center of a regulatory hub that coordinates Rac1 activation, effector exchange, and the F-actin organization state during cell signaling.

  8. show a critical role for F-actin deconstruction in cytotoxic function and immunological secretion and identify Coro1A as its mediator

  9. These results demonstrate that coronin-1a is a novel antibody target for clinically isolated syndrome and multiple sclerosis.

  10. Our findings define a new clinical entity of a primary immunodeficiency with increased susceptibility to EBV-induced lymphoproliferation (show FAS Proteins) in patients associated with hypomorphic Coronin-1A mutation.

Coronin 1a (CORO1A) Protein Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.

Alternative names and synonyms associated with Coronin 1a (CORO1A)

  • coronin, actin binding protein, 1A (CORO1A)
  • Coronin-1A (cor1a)
  • coronin, actin binding protein 1A (Coro1a)
  • coronin, actin binding protein, 1A (coro1a)
  • CLABP protein
  • CLIPINA protein
  • cor1a protein
  • CORO1A protein
  • fj83g12 protein
  • HCORO1 protein
  • Lmb3 protein
  • p57 protein
  • TACO protein
  • wu:fj83g12 protein
  • zgc:63766 protein

Protein level used designations for CORO1A

coronin, actin binding protein, 1A , Coronin-1A , coronin-1A-like , clipin-A , coronin 1 , coronin 1a , coronin-1A , coronin-like actin binding protein , coronin-like protein A , coronin-like protein p57 , tryptophan aspartate-containing coat protein , TACO , coronin-1 , actin-binding protein p57 , coronin 1A , coronin-like protein A (CLIPINA) , tryptophan aspartate-containing coat protein (TACO)

GENE ID SPECIES
454038 Pan troglodytes
710813 Macaca mulatta
100064170 Equus caballus
100195790 Salmo salar
100392238 Callithrix jacchus
100580603 Nomascus leucogenys
12721 Mus musculus
155151 Rattus norvegicus
11151 Homo sapiens
489949 Canis lupus familiaris
282196 Bos taurus
100008706 Oryctolagus cuniculus
100002113 Danio rerio
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