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Cortactin Proteins

(Cortactin (CTTN))
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
Cortactin (CTTN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Cortactin (CTTN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Cortactin (CTTN) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) (ABIN2712518)

CTTN Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD

Cortactin (CTTN) (AA 1-550) protein (His tag) Cortactin (CTTN) (AA 1-550) protein (His tag) Cortactin (CTTN) (AA 1-550) protein (His tag) (ABIN3095566)

Crystallography grade CTTN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Cortactin (CTTN) (AA 1-546) protein (His tag) Cortactin (CTTN) (AA 1-546) protein (His tag) Cortactin (CTTN) (AA 1-546) protein (His tag) (ABIN3135267)

Crystallography grade CTTN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

Cortactin Proteins by Grade

Find Cortactin Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Cortactin Proteins by Origin

Find Cortactin Proteins for a variety of species such as anti-Human Cortactin, anti-Mouse Cortactin, anti-Rat Cortactin. The species listed below are among those available. Click on a link to go to the corresponding products.

Cortactin Proteins by Source

Find Cortactin Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

Cortactin Proteins by Protein Type

Find Cortactin Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

Cortactin Proteins by Application

Find Cortactin Proteins validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Cortactin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350741
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350743
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN2712519
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7080745
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7080744
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our Cortactin Proteins

Cortés-Vicente, Gallardo, Martínez, Díaz-Manera, Querol, Rojas-García, Illa: "Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin." in: JAMA neurology, Vol. 73, Issue 9, pp. 1099-104, (2016) (PubMed).

Labrador-Horrillo, Martínez, Selva-OCallaghan, Trallero-Araguás, Grau-Junyent, Vilardell-Tarrés, Juarez: "Identification of a novel myositis-associated antibody directed against cortactin." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1008-12, (2014) (PubMed).

Gallardo, Martínez-Hernández, Titulaer, Huijbers, Martínez, Ramos, Querol, Díaz-Manera, Rojas-García, Hayworth, Verschuuren, Balice-Gordon, Dalmau, Illa: "Cortactin autoantibodies in myasthenia gravis." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).

Wang, Henry, Distefano, Wang, Räikkönen, Mönkkönen, Tanaka, Morita: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).

Llanos, Royer, Lu, Bergamaschi, Lee, Lu: "Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif." in: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43039-44, (2011) (PubMed).

Aliases for Cortactin Proteins

cortactin (CTTN) Proteins
cortactin (Cttn) Proteins
CG3637 gene product from transcript CG3637-RD (Cortactin) Proteins
cortactin S homeolog (cttn.S) Proteins
cortactin L homeolog (cttn.L) Proteins
cortactin (cttn) Proteins
src substrate cortactin (CpipJ_CPIJ006351) Proteins
Src substrate cortactin (Bm1_57220) Proteins
cortactin (LOC100533277) Proteins
1110020L01Rik Proteins
CG3637 Proteins
cortactin Proteins
cttn Proteins
Cttn Proteins
CTTN Proteins
CTTN1 Proteins
Cttnb Proteins
Dmel\CG3637 Proteins
EMS1 Proteins
Ems1 Proteins
ems1 Proteins
P85.25 Proteins
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