Browse our anti-Formin 2 (FMN2) Antibodies

Full name:
anti-Formin 2 Antibodies (FMN2)
On www.antibodies-online.com are 26 Formin 2 (FMN2) Antibodies from 10 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 28 Formin 2 products are currently listed.
Synonyms:
AU024104
list all antibodies Gene Name GeneID UniProt
FMN2 56776 Q9NZ56
FMN2 54418 Q9JL04
FMN2 289262  

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Most Popular Reactivities for anti-Formin 2 (FMN2) Antibodies

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anti-Human Formin 2 Antibodies:

anti-Mouse (Murine) Formin 2 Antibodies:

anti-Rat (Rattus) Formin 2 Antibodies:

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Top referenced anti-Formin 2 Antibodies

  1. Human Polyclonal Formin 2 Primary Antibody for ELISA, WB - ABIN566042 : Belin, Lee, Mullins: DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-½ that promotes efficient DNA repair. in eLife 2015 (PubMed)

More Antibodies against Formin 2 Interaction Partners

Human Formin 2 (FMN2) interaction partners

  1. FMN2 promotes cell survival by limiting nuclear envelope damage & DNA double-strand breaks; FMN2 is upregulated in human melanomas & disruption of FMN2 in mouse melanoma cells inhibits their extravasation & metastasis to the lung; FMN2 generates a perinuclear actin/focal adhesion system that protects the nucleus and DNA from damage to promote cell survival during confined migration & thus promote cancer metastasis.

  2. This DNA damage-induced nuclear actin assembly requires two biologically and physically linked nucleation factors: Formin-2 and Spire-1 (show SPIRE1 Antibodies)/Spire-2.

  3. We therefore characterized co-expressed Spir-2 (show SPIRE1 Antibodies) and Fmn-2 fluorescent protein fusions . The data corroborate a model according to which Spir-2 (show SPIRE1 Antibodies) exists in two different states, a cytosolic monomeric conformation and a membrane-bound state

  4. FMN2 mutations link intellectual disability either directly or indirectly to the regulation of actin-mediated synaptic spine density.

  5. miR-335 regulates the expression of at least five formin family members, three of which are validated, FMNL3, FMN2 and DAAM2.

  6. FMN2 is a crucial protein involved in the control of p21 (show CDKN1A Antibodies).

  7. results identify FMN2 as a crucial component in the regulation of p21 (show CDKN1A Antibodies) and consequent oncogene (show RAB1A Antibodies)/stress-induced cell-cycle arrest in human cells.

  8. analysis of the molecular basis of the Spir1/formin-2 interaction

  9. FMN2 was characterized at human chromosome 1q43.

  10. It is likely that FMN2 has the same function as Fmn2 in the mouse, i.e., maintenance of the meiotic spindle. Identification of patients with meiosis I arrest is necessary to determine whether FMN2 mutations are a cause of unexplained infertility.

Mouse (Murine) Formin 2 (FMN2) interaction partners

  1. FMN2 promotes cell survival by limiting nuclear envelope damage & DNA double-strand breaks; FMN2 is upregulated in human melanomas & disruption of FMN2 in mouse melanoma cells inhibits their extravasation & metastasis to the lung; FMN2 generates a perinuclear actin/focal adhesion system that protects the nucleus and DNA from damage to promote cell survival during confined migration & thus promote cancer metastasis.

  2. Fmn2 as a mediator of actin bundle integrity, enabling efficient force transmission to the adhesion sites.

  3. Data suggest formin homology domain (FH2) of Fmn2 binds actin at filament barbed end as weak capper and plays a role in displacing WASP homology domain 2 (WH2) domains of Spire-1 from actin; competitive binding of Fmn2 vs Spire-1 aids actin assembly.

  4. Spire recruits Fmn2 and facilitates its association with actin filaments barbed ends.

  5. Results suggest that the regulation of microtubule acetylation is likely a general formin (show FMN1 Antibodies) activity.

  6. analysis of the molecular basis of the Spir1/formin-2 interaction

  7. Spire1 (show SPIRE1 Antibodies) and Spire2 (show SPIRE2 Antibodies) cooperate with Formin-2 (Fmn2) to nucleate actin filaments in mouse oocytes.

  8. High formin 2 levels at meiosis I entry induce meshwork maintenance, leading to equal forces being exerted on the chromosomes, preventing spindle migration.

  9. Gene profiling of Fmn2 in Graffi murine leukemia virus-induced lymphoid leukemias suggest its important role in leukemogenesis.

  10. Fmn2 is a candidate in a QTL hotspot associated with neurobehavioral traits and gene expression in the mouse brain. Hippocampal pyramidal neurons exhibit distinct and fine granular immunoreactivity for FMN2.

Formin 2 (FMN2) Antigen Profile

Antigen Summary

Formin homology (FH) domain proteins (see FMN1\; MIM 136535) play a role in cytoskeletal organization and/or establishment of cell polarity.

Alternative names and synonyms associated with Formin 2 (FMN2)

  • formin 2 (PVX_123615) antibody
  • formin 2 (PKH_143610) antibody
  • formin 2 (FMN2) antibody
  • formin 2 (Fmn2) antibody
  • AU024104 antibody

Protein level used designations for anti-Formin 2 (FMN2) Antibodies

formin 2 , formin-2

GENE ID SPECIES
5476594 Plasmodium vivax Sal-1
7323284 Plasmodium knowlesi strain H
56776 Homo sapiens
54418 Mus musculus
775973 Gallus gallus
490366 Canis lupus familiaris
289262 Rattus norvegicus
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