Browse our anti-CXCL12 (CXCL12) Antibodies

Full name:
anti-Chemokine (C-X-C Motif) Ligand 12 Antibodies (CXCL12)
On www.antibodies-online.com are 194 Chemokine (C-X-C Motif) Ligand 12 (CXCL12) Antibodies from 28 different suppliers available. Additionally we are shipping CXCL12 Proteins (143) and CXCL12 Kits (83) and many more products for this protein. A total of 430 CXCL12 products are currently listed.
Synonyms:
a-sdf1a, IRH, Pbsf, Scyb12, SDF-1, sdf1, sdf1a, Tlsf, Tpar1, xSDF-1
list all antibodies Gene Name GeneID UniProt
CXCL12 6387 P48061
CXCL12 20315 P40224
CXCL12 24772  

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Most Popular Reactivities for anti-CXCL12 (CXCL12) Antibodies

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anti-Human CXCL12 Antibodies:

anti-Mouse (Murine) CXCL12 Antibodies:

anti-Rat (Rattus) CXCL12 Antibodies:

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Top referenced anti-CXCL12 Antibodies

  1. Human Monoclonal CXCL12 Primary Antibody for ELISA (Capture), FACS - ABIN4899704 : Villalba, Salvucci, Aoki, De La Luz Sierra, Gupta, Davis, Wyvill, Little, Yarchoan, Tosato: Serum inactivation contributes to the failure of stromal-derived factor-1 to block HIV-I infection in vivo. in Journal of leukocyte biology 2003 (PubMed)
    Show all 39 references for 4899704

  2. Human Polyclonal CXCL12 Primary Antibody for IF (p), IHC (p) - ABIN1386329 : Pei, Zeng, Han, Liao, Zhou, Li, Zhang, Liu, Zhang, Liu, Yao, Xu: Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. in Clinical journal of the American Society of Nephrology : CJASN 2014 (PubMed)
    Show all 3 references for 1386329

  3. Cow (Bovine) Polyclonal CXCL12 Primary Antibody for WB - ABIN2774605 : Sadir, Imberty, Baleux, Lortat-Jacob: Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. in The Journal of biological chemistry 2004 (PubMed)
    Show all 2 references for 2774605

  4. Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896548 : Hoellenriegel, Zboralski, Maasch, Rosin, Wierda, Keating, Kruschinski, Burger: The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization. in Blood 2014 (PubMed)
    Show all 2 references for 4896548

  5. Human Polyclonal CXCL12 Primary Antibody for EIA, WB - ABIN116227 : Schlaepfer, Audigé, Joller, Speck: TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection. in Journal of immunology (Baltimore, Md. : 1950) 2006 (PubMed)

  6. Human Monoclonal CXCL12 Primary Antibody for FACS - ABIN4896551 : Patenaude, Perreault: Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)

More Antibodies against CXCL12 Interaction Partners

Rhesus Monkey Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. these results demonstrate that a cross-talk exists between the TGF-beta1 (show TGFB1 Antibodies) and SDF-1 pathways in choroid-retinal endothelial cells

  2. following optic nerve crush, the levels of endogenous SDF-1alpha and CXCR4 (show CXCR4 Antibodies) increase in the retina and optic nerve, where activated glial cells may act as a source of increased SDF-1alpha protein.

  3. The CXCR7 (show CXCR7 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCL12 axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.

Medaka Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. primordial germ cell movements are shown to be the consequence of a combination of active SDF1a and SDF1b-guided migration; both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs

Human Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. High SDF1 expression is associated with Hepatocellular Carcinoma.

  2. GATA2 (show GATA2 Antibodies) deficiency is associated with impaired membrane expression and chemotactic dysfunctions of CXCR4 (show CXCR4 Antibodies).

  3. this study shows that CXCL12 conveys epithelial-mesenchymal transition -promoting signals in neuroendocrine tumors cells through CXCR4 (show CXCR4 Antibodies)

  4. tumor microenvironment stimulation down-regulated the migration of CCR7 (show CCR7 Antibodies)-expressing tumor cells toward CCL21 (show CCL21 Antibodies) and inhibited the formation of directional protrusions toward CCL21 (show CCL21 Antibodies) in a novel 3-dimensional hydrogel system.

  5. These findings suggest the tumor suppressor functions of CXCL12 in cervical cancer.

  6. Expressions of SDF-1, survivin (show BIRC5 Antibodies) and smac (show DIABLO Antibodies) were significantly higher in epithelial ovarian cancer tissue than those in normal tissue.

  7. These data identified the IL-4 (show IL4 Antibodies)/CXCL12 loop as a previously unrecognized pathway involved in lymphoid stroma polarization and as a potential therapeutic target in Follicular lymphoma patients.

  8. SDF-1/CXCR7 (show CXCR7 Antibodies) plays a positive role in the proliferation and invasion of endometrial carcinoma cells.

  9. analysis revealed that SYTL1 (show SYTL1 Antibodies) promotes cell migration via activation of the CXCL12/CXCR4 (show CXCR4 Antibodies) axis, as SYTL1 (show SYTL1 Antibodies) determines intracellular trafficking of CXCR4 (show CXCR4 Antibodies).

  10. Galectin-1 (show LGALS1 Antibodies)-driven production of SDF-1 in pancreatic stellate cells through activation of NF-kappaB (show NFKB1 Antibodies) promotes metastasis in pancreatic ductal adenocarcinoma.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. CXCL12 upregulation prior to stroke onset, and its actions following stroke, contribute to the endogenous, anti-inflammatory phenotype induced by repetitive hypoxic preconditioning

  2. Results suggest that SDF-1/CXCR4 (show CXCR4 Antibodies) signaling plays an important role in the dynamics associated with adult sub-ventricular zone lineage cell proliferation and differentiation.

  3. TNF (show TNF Antibodies) plays an inhibitory role in modulating myocardial SDF-1 production and blockade of TNF (show TNF Antibodies) signaling by ablation of TNFR1 (show TNFRSF1A Antibodies) and TNFR2 (show TNFRSF1B Antibodies) genes increased SDF-1 expression in the heart. These data expand on TNF (show TNF Antibodies) signaling-initiated mechanisms in myocardium, which may lend a more complete understanding of SDF-1 and TNFR (show TNFRSF1A Antibodies)-derived actions in hopes of advancing ischemic heart injury treatments.

  4. CD26 (show DPP4 Antibodies)-cleavage skews CXCL12 towards beta-arrestin dependent recruitment through ACKR3 and destroys the CXCR4 (show CXCR4 Antibodies)-mediated lymphocyte chemoattractant properties of CXCL12 in vivo

  5. these data highlight AnxA1 (show ANXA1 Antibodies) as a novel determinant of neutrophil maturation and the mechanisms behind blood neutrophil homing to BM via the CXCL12/CXCR4 (show CXCR4 Antibodies) pathway.

  6. CXCL12/CXCR4 (show CXCR4 Antibodies) regulates HA and LG following corneal suture placement, and provides a novel strategy to inhibit LG. Notably, the present study is the first to demonstrate evidence that CXCL12/CXCR4 (show CXCR4 Antibodies) modulates LG in a corneal suture-induced mouse model.

  7. Female MRL/lpr (show FAS Antibodies) mice treated with dual blockade of the chemokines CCL2 (show CCL2 Antibodies) and CXCL12 showed significantly more effective than either monotherapy in preventing proteinuria and immune complex glomerulonephritis.

  8. the present study indicates that the CXCL12/CXCR4 (show CXCR4 Antibodies) signaling pathway is important during the development of cochleae in neonatal mice.

  9. crosstalk between astrocytic CXCL12 and microglial CXCR4 (show CXCR4 Antibodies) in the pathogenesis of neuropathic pain.

  10. A model of SDF-1 regulation in the hypoxia pathway was constructed; the underlying mechanisms of SDF-1 kinetics and a novel incoherent feed forward loop regulating SDF-1 expression were proposed.

Xenopus laevis Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. expression patterns of xSDF-1a, xCXCR4, and xCXCR7 during gastrulation; results suggest SDF-1 signaling supports migration of the mesendoderm cell cohort toward the animal pole and that activin/nodal signaling acts as a regulator of the expression of xSDF-1a and xCXCR4, but not xCXCR7

  2. SDF-1/CXCR4 chemokine (show CCL1 Antibodies) signaling is involved in the migration and survival or in the differentiation of PGCs in Xenopus

  3. A significant increase of stromal cell-derived factor-1alpha and CXCR4 was observed in protein extracts of idiopathic inflammatory myopathies in comparison with normal controls.

  4. SDF-1 signaling is necessary for migrations of massive numbers of cells during gastrulation.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance.

  2. The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 (show CXCR4 Antibodies) axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 12 (CXCL12) interaction partners

  1. There is a potential link between follicular SDF1/CXCR4 (show CXCR4 Antibodies) activation and the regulation of ovulation-related genes in cows and horses.

  2. Polymorphism of intron 2 of the SDF1 gene in Galloway, Hereford, and Russian Black Pied cattle

CXCL12 Antigen Profile

Antigen Summary

This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CXCL12

  • chemokine (C-X-C motif) ligand 12 (CXCL12) antibody
  • CXCL12 (LOC100304642) antibody
  • stromal cell-derived factor 1a (sdf1a) antibody
  • stromal cell-derived factor 1a (a-sdf1a) antibody
  • chemokine (C-X-C motif) ligand 12 (Cxcl12) antibody
  • chemokine (C-X-C motif) ligand 12 (cxcl12) antibody
  • a-sdf1a antibody
  • IRH antibody
  • Pbsf antibody
  • Scyb12 antibody
  • SDF-1 antibody
  • sdf1 antibody
  • sdf1a antibody
  • Tlsf antibody
  • Tpar1 antibody
  • xSDF-1 antibody

Protein level used designations for CXCL12

chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) , chemokine CXCL12/SDF-1ALPHA , stromal cell-derived factor 1 , stromal cell-derived factor 1 isoform alpha , stromal cell-derived factor 1 isoform gamma , CXCL12 , stromal cell-derived factor 1a , intercrine reduced in hepatomas , pre-B cell growth-stimulating factor , 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 , pre-B-cell growth-stimulating factor , thymic lymphoma cell-stimulating factor , C-X-C motif chemokine 12 , stromal-derived factor 1 , chemokine ligand 12b , stromal cell derived factor 1 , stromal cell-derived factor-1 beta , CXC chemokine , CXCL12 chemokine , SDF-1 gamma , Stromal cell-derived factor 1 , stromal cell-derived factor-1 gamma

GENE ID SPECIES
574334 Macaca mulatta
100173045 Pongo abelii
100304642 Ictalurus punctatus
100049305 Oryzias latipes
100170634 Oryzias latipes
6387 Homo sapiens
20315 Mus musculus
399030 Xenopus laevis
395180 Gallus gallus
449622 Canis lupus familiaris
494460 Sus scrofa
613811 Bos taurus
24772 Rattus norvegicus
100721137 Cavia porcellus
493806 Felis catus
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