Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species
Human CXCR4 ELISA Kit for Sandwich ELISA - ABIN417543
Shanmugam, Manu, Ong, Ramachandran, Surana, Bist, Lim, Kumar, Hui, Sethi: Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model. in International journal of cancer. Journal international du cancer 2011
Show all 8 Pubmed References
Human CXCR4 ELISA Kit for Sandwich ELISA - ABIN365079
Mosevoll, Akkök, Hervig, Melve, Bruserud, Reikvam: Stem cell mobilization and harvesting by leukapheresis alters systemic cytokine levels in patients with multiple myeloma. in Cytotherapy 2013
Rat (Rattus) CXCR4 ELISA Kit for Sandwich ELISA - ABIN367433
Sato, Otani, Fujita, Shimazu, Yoshioka, Enoki, Minato, Iwasaka: Granulocyte colony-stimulating factor does not enhance recruitment of bone marrow-derived cells in rats with acute myocardial infarction. in Experimental and clinical cardiology 2013
bilateral lineup in the trunk before PGC migration colonizing gonadal areas is defective in PGCS expressing a missense mutation in chemokine receptor gene cxcr4b
results characterize CXCR4 as an important pathway that modulates immune dysfunction and mortality following sepsis, which may hold promise as a target for future therapeutic intervention in septic patients
CXCL12 (show CXCL12 ELISA Kits)/CXCR4 signaling negatively modulates the bipotential state of Hemogenic endothelial cells independently of the hematopoietic fate.
Efficient plasma cell differentiation and trafficking require Cxcr4 desensitization.
High CXCR4 expression is associated with Prostate Cancer.
Data show that FLT3 ligand (FLT3L (show FLT3LG ELISA Kits)) enhances thymopoiesis through increased survival and export of hematopoietic stem cell (Lin([minus])Sca1 (show ATXN1 ELISA Kits)(+)c-Kit (show KIT ELISA Kits)(+) [LSK (show LCK ELISA Kits)] cells via CXCR4 receptor regulation.
Adipocytes promoted osteoclast differentiation, function and expression of adhesion-related molecules through the CXCL12 (show CXCL12 ELISA Kits)/CXCR4 signalling pathway.
Efficient Cxcr4 desensitization is critical for lymphoid differentiation of hematopoietic stem and progenitor cell (HSPC (show PSMA7 ELISA Kits)), and its impairment is a key mechanism underpinning the lymphopenia observed in mice and likely in WHIM Syndrome (WS) patients.
COUP-TFI (show NR2F1 ELISA Kits) is required predominantly in Dentate gyrus progenitors for modulating expression of the Cxcr4 receptor during granule cell neurogenesis and migration.
CXCR4, CCR2 (show CCR2 ELISA Kits), and CX3CR1 (show CX3CR1 ELISA Kits) direct dendritic cell precursors from the bone marrow to the lung differentially.
data suggest that prolonged but reversible pharmacologic blockade of the CXCR4/CXCL12 axis represents an approach that releases HSPC with efficiency superior to any other known mobilization strategy and may also serve as an effective method to expand the BM HSPC pool.
data indicated that MALAT1 might play an oncogenic role in hilar cholangiocarcinoma (HCCA) through miR (show MLXIP ELISA Kits)-204-dependent CXCR4 regulation, and could be regarded as a therapeutic target in HCCA.
Studies indicate that ibrutinib is active in patients with Waldenstrom macroglobulinemia (WM) and is affected by MYD88 (show MYD88 ELISA Kits) and CXCR4 mutation status.
knockdown of CXCR4 in human embryonic stem cells also blocked the neural induction and cells with reduced CXCR4 were rarely positive for Nestin (show NES ELISA Kits) and Sox1 (show SOX1 ELISA Kits)-staining
findings indicate that CXCR4 activation attenuates thrombin (show F2 ELISA Kits)-induced lung endothelial barrier function impairment and suggest that protective effects of CXCL12 (show CXCL12 ELISA Kits) are dictated by its CXCR4 agonist activity and interactions of distinct protein moieties with heparan sulfate on the endothelial surface
Together, these data indicate that different mechanisms govern the flow response across GSCs, but that within a single patient, there are subpopulations of GSCs that respond to flow via either CD44 (show CD44 ELISA Kits)- or CXCR4-CXCL12 (show CXCL12 ELISA Kits) mechanisms.
JAM (show F11R ELISA Kits) family members differentially regulate CXCR4 function and CXCL12 (show CXCL12 ELISA Kits) secretion in the bone marrow niche.
through its interaction with CXCR4 and the actin cytoskeleton, drebrin (show DBN1 ELISA Kits) regulates T cell activation. CD4 (show CD4 ELISA Kits)(+) T cells are one of the main targets for the human immunodeficiency virus (HIV)-1.
Data indicate that a constitutively monomeric CXCL12 (show CXCL12 ELISA Kits) variant reproduced the G protein-dependent and beta-arrestin-dependent responses that are associated with normal CXCR4 signaling and lead to cell migration.
High CXCR4 expression is associated with chronic lymphocytic leukaemia in comparison to small lymphocytic lymphoma.
SDF-1 (show CXCL12 ELISA Kits)/CXCR4 axis plays a crucial role in engraftment; however, more studies are warranted to assess their expression post-transplant.
CXCR4 controls leukocyte mobilization after trauma.
The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1 (show CXCL12 ELISA Kits)/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration.
reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 ELISA Kits) and CXCL2 (show CXCL2 ELISA Kits) and of chemokine (show CCL1 ELISA Kits) receptors CCR2 (show CCR2 ELISA Kits), CCR5, and CXCR4 following coronary angioplasty
The current analysis failed in identifying a causal mutation on the CXCR4 gene underlying a previously reported quantitative trait loci for cattle trypanotolerance on bovine chromosome 2.
There is a potential link between follicular SDF1 (show CXCL12 ELISA Kits)/CXCR4 activation and the regulation of ovulation-related genes in cows and horses.
The combination of low expression of CXCR4 and high expression of IL-10 (show IL10 ELISA Kits) might be closely concerned with some bias for the production of PI calves.
The increased CXCR4 and CXCR7 (show CXCR7 ELISA Kits) expression resulted in increased SDF-1 (show CXCL12 ELISA Kits)-induced RF/6A cell migration and tube formation.
The CXCR7 (show CXCR7 ELISA Kits)/CXCR4/CXCL12 (show CXCL12 ELISA Kits) axis plays an important role in the formation of CNV, and may become a novel target for the treatment of choroidal neovascularization-associated diseases.
These findings suggest that FBLN5 (show FBLN5 ELISA Kits) may interfere with choroidal neovascularization by downregulating VEGF (show VEGFA ELISA Kits), CXCR4, and TGFB1 (show TGFB1 ELISA Kits) expression and inhibiting choroidl endothelial cell proliferation.
Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 almost exclusively
Arteries are formed by vein-derived endothelial tip cells, this process critically depends on chemokine receptor Cxcr4 function.
SDF1a (show CXCL12 ELISA Kits) directly controls the migration of both leading and trailing edges of a tissue through the activation of two independent receptors, CXCR4b and CXCR7 (show CXCR7 ELISA Kits).
Hoxb8a is induced by and cooperates with Wnt (show WNT2 ELISA Kits) signaling to up-regulate cxcr4b, and acts through multiple mechanisms to repress cxcr7b expression.
Expression of Cxcr4 and Cxcl12 (show CXCL12 ELISA Kits) in radial glial cells of the adult zebrafish brain supports important roles for the Cxcl12 (show CXCL12 ELISA Kits)/Cxcr4 pair in brain development and functioning.
show that inactivation of the estrogen receptor ESR1 (show ESR1 ELISA Kits) results in ectopic expression of cxcr4b throughout the primordium, whereas ESR1 (show ESR1 ELISA Kits) overexpression results in a reciprocal reduction in the domain of cxcr4b expression.
Study suggest that the Cxcl12a-Cxcr4b ligand-receptor pair are involved in the migration of GnRH3 neurons in zebrafish, and are therefore crucial for the development of this system.
A CXCR4-like chemokine receptor is expressed by the migrating lateral line primordium cells. Both the formation and the innervation of this system depend on the SDF1 (show CXCL12 ELISA Kits)-CXCR4 system.
Knocking down CXCR4 results in severe defects in primordial germ cell migration.
SDF-1 (show CXCL12 ELISA Kits)/CXCR4 signaling is important for guiding retinal ganglion cell axons within the retina to the optic stalk to exit the retina.
chemokine (show CCL1 ELISA Kits) signaling contributes to both the olfactory placode assembly and the olfactory sensory neurons axon pathfinding in zebrafish
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
C-X-C chemokine receptor type 4
, SDF-1 receptor
, Stromal cell-derived factor 1 receptor
, chemokine (C-X-C motif) receptor 4
, chemokine (C-X-C) receptor 4
, chemokine receptor 4
, leukocyte-derived seven transmembrane domain receptor
, leukocyte-expressed seven-transmembrane-domain
, pre-B-cell-derived chemokine receptor
, stromal cell-derived factor 1 receptor
, CXC chemokine receptor
, chemokine receptor (LCR1)
, CD184 antigen
, leukocyte-derived seven-transmembrane-domain receptor
, lipopolysaccharide-associated protein 3
, neuropeptide Y receptor Y3
, seven transmembrane helix receptor
, seven-transmembrane-segment receptor, spleen
, C-X-C chemokine receptor type 4-B
, SDF-1 receptor B
, SDF-1 receptor-B
, Stromal cell-derived factor 1 receptor-B
, stromal cell-derived factor 1 receptor B
, chemokine receptor CXCR4
, CXC chemokine receptor 4