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anti-Human TTL Antibodies:
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Human Polyclonal TTL Primary Antibody for EIA, WB - ABIN955382
Dick, Meyers, Aliev, Nurnberger, Kramer, Kuperman, Porjesz, Tischfield, Edenberg, Foroud, Schuckit, Goate, Hesselbrock, Bierut: Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010
Show all 4 references for ABIN955382
Chicken Polyclonal TTL Primary Antibody for WB - ABIN2785284
Erck, MacLeod, Wehland: Cloning and genomic organization of the TTL gene on mouse chromosome 2 and human chromosome 2q13. in Cytogenetic and genome research 2003
Tubulin-tyrosine ligase (TTL) is required to increase the levels of tyrosinated alpha-tubulin (show TUBA4A Antibodies) at the axon injury site and plays an important role in injury signaling.
Our results show that MAP1B (show MAP1B Antibodies) abd tubulin-tyrosine ligase indeed interact and that the interaction is not affected by MAP1B (show MAP1B Antibodies) phosphorylation.
TTL is a cytosolic enzyme involved in the posttranslational modification of alpha-tubulin (see MIM 602529). Alpha-tubulin within assembled microtubules is detyrosinated over time at the C terminus. After microtubule disassembly, TTL restores the tyrosine residues and consequently participates in a cycle of tubulin detyrosination and tyrosination (Erck et al., 2003
, tubulin--tyrosine ligase
, tubulin-tyrosine ligase