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TTL antibody

TTL Reactivity: Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7076048
  • Target See all TTL Antibodies
    TTL (Tubulin tyrosine Ligase (TTL))
    Reactivity
    • 29
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 26
    • 3
    Rabbit
    Clonality
    • 26
    • 3
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    This TTL antibody is un-conjugated
    Application
    • 22
    • 21
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse TTL
  • Application Notes
    IHC/IF (M,R) 1:2000-1:4000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    TTL (Tubulin tyrosine Ligase (TTL))
    Alternative Name
    TTL (TTL Products)
    Synonyms
    2410003M22Rik antibody, 2700049H19Rik antibody, AI848570 antibody, wu:fb93a09 antibody, zgc:153332 antibody, tubulin tyrosine ligase antibody, Ttl antibody, TTL antibody, ttl antibody
    Background
    Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.
    Gene ID
    69737
    NCBI Accession
    NP_081468
    UniProt
    P38585
    Pathways
    Regulation of Cell Size
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