Browse our CNTN2 Proteins (CNTN2)

Full name:
Contactin 2 (Axonal) Proteins (CNTN2)
On are 12 Contactin 2 (Axonal) (CNTN2) Proteins from 8 different suppliers available. Additionally we are shipping CNTN2 Antibodies (70) and CNTN2 Kits (21) and many more products for this protein. A total of 109 CNTN2 products are currently listed.
AXONIN-1, AXT, CNTN2, D130012K04Rik, si:dz37k09.2, TAG-1, TAG-564, TAG1, TAX, TAX1
list all proteins Gene Name GeneID UniProt
CNTN2 21367 Q61330
CNTN2 6900 Q02246
Rat CNTN2 CNTN2 25356 P22063

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CNTN2 Proteins (CNTN2) by Origin

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Top referenced CNTN2 Proteins

  1. Human CNTN2 Protein expressed in Human Cells - ABIN2002881 : Hasler, Rader, Stoeckli, Zuellig, Sonderegger: cDNA cloning, structural features, and eucaryotic expression of human TAG-1/axonin-1. in European journal of biochemistry / FEBS 1993 (PubMed)
    Show all 5 references for 2002881

  2. Mouse (Murine) CNTN2 Protein expressed in Human Cells - ABIN2008631 : Milev, Maurel, Häring, Margolis, Margolis: TAG-1/axonin-1 is a high-affinity ligand of neurocan, phosphacan/protein-tyrosine phosphatase-zeta/beta, and N-CAM. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for 2008631

  3. Human CNTN2 Protein expressed in HEK-293 Cells - ABIN2180893 : Tsiotra, Karagogeos, Theodorakis, Michaelidis, Modi, Furley, Jessell, Papamatheakis: Isolation of the cDNA and chromosomal localization of the gene (TAX1) encoding the human axonal glycoprotein TAG-1. in Genomics 1994 (PubMed)
    Show all 2 references for 2180893

More Proteins for CNTN2 Interaction Partners

Zebrafish Contactin 2 (Axonal) (CNTN2) interaction partners

  1. The expression patterns of contactin-2 at different time points after spinal cord injury were studied at the mRNA level.

  2. two guidance cues, TAG-1 and laminin-alpha1, influence the behavior of growth cones during axon pathfinding in vivo

  3. tag1, lama1 (show LAMA1 Proteins) and vangl2 (show VANGL2 Proteins) participate in a common mechanism that integrates signaling between the FBMN and its environment to regulate migration.

Mouse (Murine) Contactin 2 (Axonal) (CNTN2) interaction partners

  1. We further demonstrate that Cre expression initiates after birth with preservation of native Cntn2 protein. Finally, we show that Cntn23'UTR-IRES-Cre-EGFP/+ mice maintain normal cardiac mechanical and electrical function.

  2. Tag1 is crucial for the olfactory circuit formation in mice.

  3. Interaction proteomics revealed the interactors of Caspr2 (show CNTNAP2 Proteins), including CNTN2, KCNAs, members of the ADAM family (ADAM22 (show ADAM22 Proteins), ADAM23 (show Adam23 Proteins) and ADAM11 (show ADAM11 Proteins)), members of LGI family and MAGUKs (DLGs and MPPs (show MPHOSPH6 Proteins)).

  4. Our results clearly demonstrate that mouse and human contactin-2 are physiological substrates for BACE1 (show BACE Proteins)

  5. the TAG-1-mediated cell-to-cell interaction between the unpolarized multipolar cells and the pioneering axons regulates the polarization of multipolar cells partly through Lyn kinase and Rac1

  6. This study demonistrated that knockdown of the cell-surface molecule TAG-1 resulted in retraction of neocortical progenitors' basal processes.

  7. These results suggest that the Tax-induced decline in p53 (show TP53 Proteins) function, which is independent of NF-kappaB (show NFKB1 Proteins) activation in the early stage, might be the first stage in the onset of ATLL.

  8. two novel genes, Cntnap2 (show CNTNAP2 Proteins) and Tag1, are implicated in the regulation of diet-induced obesity.

  9. These observations identify a novel role for TAG1 in modulating the intracellular sorting of signaling receptor complexes.

  10. These findings are consistent with a regulatory role for Tag-1 in axon emergence as well as migratory behavior by developing mouse cerebellar granule neurons.

Human Contactin 2 (Axonal) (CNTN2) interaction partners

  1. the ectodomains of CNTNAP2 (show CNTNAP2 Proteins) and contactin 2 (CNTN2) bind directly and specifically, with low nanomolar affinity.

  2. RACK1 (show GNB2L1 Proteins) interacts with CNTN2, and the effects of RACK1 (show GNB2L1 Proteins) on glioma cell growth and differentiation are mediated by CNTN2.

  3. Our results clearly demonstrate that mouse and human contactin-2 are physiological substrates for BACE1 (show BACE Proteins)

  4. A single nucleotide deletion in exon 6 of CNTN2 results in a frameshift mutation, segregating in a recessive manner in a consanguineous Egyptian family with epilepsy.

  5. allelic variation in TAG-1 does not play a major role in determining multifocal motor neuropathy susceptibility.

  6. single nucleotide polymorphisms in TAG-1 are related to the IVIg responsiveness of Chronic inflammatory demyelinating polyneuropathy patients.

  7. The domains responsible for the neurite outgrowth promoting activity of TAG-1 have been investigated as well as its interactions with other cell adhesion molecules.

  8. TAG-1 homophilic interaction is based on dimer formation rather than formation of a molecular zipper as proposed for the chicken ortholog.

  9. Contactin-2 is expressed by various neuronal populations and sequestered in the juxtaparanodal domain of myelinated axons both at the axonal and myelin sides; is an autoantigen targeted by T cells and autoantibodies in MS.

  10. immune response to CNTN2 and possible involvement in multiple sclerosis and EAE [REVIEW]

CNTN2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.

Alternative names and synonyms associated with CNTN2

  • contactin 2 (cntn2)
  • contactin 2 (axonal) (CNTN2)
  • contactin 2 (Cntn2)
  • contactin 2 (axonal) (Cntn2)
  • AXONIN-1 protein
  • AXT protein
  • CNTN2 protein
  • D130012K04Rik protein
  • si:dz37k09.2 protein
  • TAG-1 protein
  • TAG-564 protein
  • TAG1 protein
  • TAX protein
  • TAX1 protein

Protein level used designations for Contactin 2 (Axonal) Proteins (CNTN2)

contactin-2 , transiently expressed axonal glycoprotein , contactin 2 (axonal) , TAX-1 , axonal glycoprotein TAG-1 , axonin , axonin-1 , transient axonal glycoprotein 1 , transiently-expressed axonal glycoprotein , axonin-1 cell adhesion molecule , contactin 2 (transiently expressed)

30726 Danio rerio
457662 Pan troglodytes
528595 Bos taurus
100171864 Pongo abelii
21367 Mus musculus
6900 Homo sapiens
419825 Gallus gallus
25356 Rattus norvegicus
100357508 Oryctolagus cuniculus
100721266 Cavia porcellus
100685268 Canis lupus familiaris
101113348 Ovis aries
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