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Browse our Metabotropic Glutamate Receptor 5 (GRM5) ELISA Kits

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Glutamate Receptor, Metabotropic 5 ELISA Kits (GRM5)
On are 17 Glutamate Receptor, Metabotropic 5 (GRM5) ELISA Kits from 5 different suppliers available. Additionally we are shipping Metabotropic Glutamate Receptor 5 Antibodies (156) and Metabotropic Glutamate Receptor 5 Proteins (7) and many more products for this protein. A total of 187 Metabotropic Glutamate Receptor 5 products are currently listed.
6430542K11Rik, AI850523, Glu5R, Gprc1e, mGlu5, mGlur5, mGluR5b

Metabotropic Glutamate Receptor 5 (GRM5) ELISA Kits by Reactivity

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More ELISA Kits for Metabotropic Glutamate Receptor 5 Interaction Partners

Human Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. Decrease of mGluR5 receptor density goes parallel with changes in enkephalin and substance P (show TAC1 ELISA Kits) immunoreactivity in Huntington's disease

  2. The metabotropic glutamate (show GRIN1 ELISA Kits) receptor subtype 5 (mGluR5) has been implicated in the pathophysiology of mood and anxiety disorders.

  3. The interaction between GRM5 and cellular prion protein (show PRNP ELISA Kits) has a central role in transgenic mouse model of Alzheimer's disease pathogenesis.

  4. Data suggest that metabotropic glutamate (show GRIN1 ELISA Kits) receptors recycling is completely dependent on the activity of PP2A (show PPP2R4 ELISA Kits) whereas, PP2B (show CAN ELISA Kits) has partial effect on this process.

  5. findings provide evidence for decreased expression of metabotropic glutamate receptor 5 and its signaling components representing a key pathophysiological hallmark in autism spectrum disorder.

  6. Study provided evidence that protein expression of mGluR5 is significantly higher (total: 42%; monomer: 25%; dimer: 52%) in the hippocampal CA1 (show CA1 ELISA Kits) region of schizophrenia subjects relative to healthy controls

  7. Results provide compelling evidence that mGluR5 regulation is altered in schizophrenia, likely contributing to the altered glutamatergic signaling that is associated with the disorder

  8. This review supports altered mGluR5 functioning as a convergent point in ASD (show ARSD ELISA Kits) pathogenesis and indicates more research is warranted into mGluR5 as a potential therapeutic target.

  9. both an increased and reduced mGlu5 functioning seem to be associated with Intellectual Disability and autism spectrum disorders.

  10. Findings suggest that mGluR2 (show GRM2 ELISA Kits)/3 and mGluR5s are unaltered in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia

Mouse (Murine) Glutamate Receptor, Metabotropic 5 (GRM5) interaction partners

  1. mGluR5 may mediate amyloid beta synaptotoxicity and it is a novel therapeutic targets for AD and other cognitive syndromes.

  2. Dysregulation of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  3. Our findings suggest a fundamental role for mGluR5 in the development of Pv(+) neurons and show that alterations in this system can produce broad-spectrum alterations in brain network activity

  4. This work provides strong evidence that Homer (show HOMER1 ELISA Kits)-mGlu5 binding contributes to symptoms associated with neurodevelopmental disorders

  5. This study identify highly specialized roles of lateral septal mGluR5 and Oxtr (show OXTR ELISA Kits) in the the regulation of discrete social behaviors, and suggest that deficits in social interactions.

  6. Results offer the first evidence that changes in the striatal expression of mGlu4 (show GRM4 ELISA Kits) and mGlu5 receptors occur in acute models of parkinsonisms

  7. We show for the first time that knockdown of mGlu5 in the dorsal hippocampus is sufficient to impair spatial learning in Morris Water Maze

  8. The results of this study demonstrated an important role for mGlu5 in environmental modulation of schizophrenia-related behavioral impairments.

  9. chronic postnatal down-regulation of mGluR5 signaling produces coordinated impairments in both NMDAR (show GRIN1 ELISA Kits)-dependent LTD in vitro and ocular dominance plasticity in vivo.

  10. mGluR5 blockage elicits distinct outcomes in terms of locomotor activity and motor coordination depending on the brain region injected with mGluR5 antagonist.

Metabotropic Glutamate Receptor 5 (GRM5) Antigen Profile

Antigen Summary

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Metabotropic Glutamate Receptor 5 (GRM5)

  • glutamate receptor, metabotropic 5 (GRM5) Elisa Kit
  • glutamate receptor, metabotropic 5 (Grm5) Elisa Kit
  • 6430542K11Rik Elisa Kit
  • AI850523 Elisa Kit
  • Glu5R Elisa Kit
  • Gprc1e Elisa Kit
  • mGlu5 Elisa Kit
  • mGlur5 Elisa Kit
  • mGluR5b Elisa Kit

Protein level used designations for GRM5

metabotropic glutamate receptor 5 , metabotropic glutamate receptor 5 variant F , metabotropic glutamate receptor 5 variant G , metabotropic glutamate receptor 5 variant H , metabotropic glutamate receptor (mGluR5) , metabotropic glutamate receptor 5b , G protein coupled receptor, family C, group 1, member E , G protein-coupled receptor GRM5 , G protein-coupled receptor, family C, group 1, member E , metabotropic glutamate receptor subtype 5b , metabotropic glutamate receptor type 5

373933 Gallus gallus
2915 Homo sapiens
24418 Rattus norvegicus
108071 Mus musculus
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