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PX domain of zebrafish SNX25 (zSNX25-PX) is capable of binding to PI3P only in its dimeric form
This study confirmed that SNX25 as genetic modifiers of age at onset of Alzheimer disease.
upregulation of SNX25 might be involved in the development of temporal lobe epilepsy.
SNX25 negatively regulates TGF-beta (show TGFB1 Proteins) signaling by enhancing the receptor degradation through lysosome pathway.
May be involved in several stages of intracellular trafficking (By similarity).
, sorting nexin 25
, cellular trafficking protein
, sorting nexin-25-like