Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all species
Show all synonyms
Select your species and application
anti-Human ARNT Antibodies:
anti-Mouse (Murine) ARNT Antibodies:
anti-Rat (Rattus) ARNT Antibodies:
Go to our pre-filtered search.
Cow (Bovine) Polyclonal ARNT Primary Antibody for ChIP, GS - ABIN151037
Sulentic, Holsapple, Kaminski: Putative link between transcriptional regulation of IgM expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin and the aryl hydrocarbon receptor/dioxin-responsive enhancer signaling pathway. in The Journal of pharmacology and experimental therapeutics 2000
Show all 33 Pubmed References
Cow (Bovine) Monoclonal ARNT Primary Antibody for ChIP, GS - ABIN151055
Alam, Maizels, Park, Ghaey, Feiger, Chandel, Hunzicker-Dunn et al.: Follicle-stimulating hormone activation of hypoxia-inducible factor-1 by the phosphatidylinositol 3-kinase/AKT/Ras homolog enriched in brain (Rheb)/mammalian target of rapamycin (mTOR) pathway is ... in The Journal of biological chemistry 2004
Show all 89 Pubmed References
Human Monoclonal ARNT Primary Antibody for IF, WB - ABIN968356
Ambrosini, Nath, Sierra-Honigmann, Flores-Riveros: Transcriptional activation of the human leptin gene in response to hypoxia. Involvement of hypoxia-inducible factor 1. in The Journal of biological chemistry 2002
Show all 6 Pubmed References
Amphibian Monoclonal ARNT Primary Antibody for GS, ICC - ABIN152684
Singh, Wyman, Casado, Garrett, Gasiewicz: Treatment of mice with the Ah receptor agonist and human carcinogen dioxin results in altered numbers and function of hematopoietic stem cells. in Carcinogenesis 2009
Show all 9 Pubmed References
Human Monoclonal ARNT Primary Antibody for IF, WB - ABIN968355
Drutel, Kathmann, Heron, Schwartz, Arrang: Cloning and selective expression in brain and kidney of ARNT2 homologous to the Ah receptor nuclear translocator (ARNT). in Biochemical and biophysical research communications 1996
Show all 5 Pubmed References
Human Monoclonal ARNT Primary Antibody for FACS, IF - ABIN2452782
Hao, Bhakti, Peet, Whitelaw: Reciprocal regulation of the basic helix-loop-helix/Per-Arnt-Sim partner proteins, Arnt and Arnt2, during neuronal differentiation. in Nucleic acids research 2013
Human Polyclonal ARNT Primary Antibody for IF, WB - ABIN513506
Miranda, Nordgren, Male, Lawrence, Hoakwie, Cuda, Court, Fox, Townsend, Packham, Eccles, Tavassoli: A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. in Journal of the American Chemical Society 2013
Cow (Bovine) Polyclonal ARNT Primary Antibody for WB - ABIN2777195
Kurlak, Mistry, Cindrova-Davies, Burton, Broughton Pipkin: Human placental renin-angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia-reoxygenation insult. in The Journal of physiology 2016
Morpholino experiments show that knockdown of ARNT1 offers protection from TCCD-induced cardiotoxicity.
The structure clearly disclosed that AhRR (show CYP1A1 Antibodies) competitively represses AhR (show AHR Antibodies) binding to ARNT and target DNA and further suggested the existence of an AhRR (show CYP1A1 Antibodies)-ARNT-specific repression mechanism. This study provides a structural basis for understanding the mechanism by which AhRR (show CYP1A1 Antibodies) represses AhR (show AHR Antibodies)-mediated gene transcription.
Study showed that polymorphism rs2228099 of the ARNT gene could be a novel susceptibility gene to essential hypertension.
The results revealed a HIF-1alpha (show HIF1A Antibodies)-dependent mechanism leading to ARNT upregulation in hypoxia.
The protein levels of phosphorylated (p)Akt, Erk1/2, pErk1/2, HIF1alpha and HIF1beta were significantly increased by 5.89, 0.5, 0.59, 1.46 and 0.92fold, respectively, in the patients with PAH, compared with those in the controls group
Report quinone-mediated induction of cytochrome P450 1A1 (show CYP1A1 Antibodies) in HepG2 cells through increased interaction of aryl hydrocarbon receptor (show AHR Antibodies) with aryl hydrocarbon receptor nuclear translocator.
this study shows that ARNT is upregulated in skin from atopic dermatitis patients in China
Data suggest that activation of the AhR (show AHR Antibodies)/ARNT (aryl hydrocarbon receptor/aryl hydrocarbon receptor (show AHR Antibodies) nuclear translocator) signaling by AhR (show AHR Antibodies) ligands (environmental carcinogens TCDD/3MC/PCB (show PC Antibodies) used here) represents novel mechanism for regulating the expression of ADH1B (alcohol dehydrogenase 1B (show ADH1B Antibodies)) and other isoenzymes (ADH4 (show ADH4 Antibodies), ADH6 (show ADH6 Antibodies)) in hepatocytes.
Authors report here that not only HIF1alpha but also ARNT regulates VEGF expression in 3D cancer spheroids. Results suggest the utility of the in vitro 3D cancer spheroid model for investigating angiogenesis in cancerous tissues.
The results of this study indicate that ARNT depletion renders tumour cells susceptible to radiation whereas overexpression of this transcription factor confers radioresistance
HIF-1beta might act as a novel cross-link between the HIF and NF-kappaB (show NFKB1 Antibodies) pathways in suppression of angiogenesis by LDL, while proteasome inhibitors might promote angiogenesis by reactivating this signaling cascade under hyperlipidemia.
These promoters possess potential signature sequences for common as well as different transcription factors suggesting complex regulation of Arnt gene.
The only in vivo defects found in beta-Arnt mice were significant increases in the respiratory exchange ratio and in vivo carbohydrate oxidation, and a decrease in lipid oxidation
hepatocyte ARNT is not a requirement for initiation of liver fibrogenesis, but does regulate pro-fibrotic gene expression and macrophage accumulation.
HIF-1beta hepatocyte-specific knockout mice had less liver injury and steatosis in response to Gao-binge ethanol treatment.
Candidate gene analysis focused on Arnt as an influence on circadian regulation in the 'drinking in the dark' phenotype of alcohol consumption.
crystal structures for each of mouse HIF-2alpha (show EPAS1 Antibodies)-ARNT and HIF-1alpha (show HIF1A Antibodies)-ARNT heterodimers in states that include bound small molecules and their hypoxia response element
We determined that ARNT is essential for adult and fetal hematopoietic stem cell viability and homeostasis.
ARNT is a critical regulator of myocardial fatty acid metabolism and its deletion leads to cardiomyopathy and an increase in triglyceride accumulation through PPARA (show PPARA Antibodies).
This study demonstrates for the first time the requirement of HIF1 (show SETD2 Antibodies) for FSH (show BRD2 Antibodies)-regulated Vegfa (show VEGFA Antibodies) expression in vivo and that HIF1 (show SETD2 Antibodies) acts via a single hypoxia response element in the Vegfa (show VEGFA Antibodies) promoter to exert its regulatory functions.
Outcomes for islet transplants lacking beta-cell ARNT were poor.
The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1\;12)(q21\;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants.
aryl hydrocarbon receptor nuclear translocator
, aryl hydrocarbon receptor nuclear translocater
, ARNT protein
, HIF-1 beta
, dioxin receptor, nuclear translocator
, hypoxia-inducible factor 1 beta
, hypoxia-inducible factor 1-beta
, class E basic helix-loop-helix protein 2
, hypoxia-inducible factor 1, beta subunit
, Aryl hydrocarbon receptor nuclear translocator 1